JF
J. Favier
paragangliomaParagangliomaPheochromocytomapheochromocytomaAdrenal Gland NeoplasmsGerm-Line Mutationsuccinate dehydrogenaseGenetic Predisposition to DiseaseMutationSDHB
On Valency
published · living versionsW_4wjzqtpm·v1 · currentpublished
Measurement of the neutrino velocity with the OPERA detector in the CNGS beam
with The OPERA Collaboration, T. Adam, N. Agafonova, A. Aleksandrov +186
1 version
Preprints & journals
117 papers in the corpus · 1999–2026Report of the scientific network Holimitox on succinate dehydrogenase inhibitor (SDHI) pesticides: new insights and challenges with an EcoHealth approach-presentations and round tables from the Holimitox day on November 7, 2024.42192070 · Bonmatin, Jean-Marc, Chamaraux, François, Jean, Séverine et al.2026 · 1 citationEnvironmental science and pollution research international. 2026;33(18):9131-9142
Unbiased CRISPR synthetic lethal screening for genetic vulnerabilities in a succinate dehydrogenase-loss model of paraganglioma.42181244 · Al Khazal, Fatimah J, Emch, Michael J, Correia, Cristina et al.2026 · 2 citationsiScience. 2026;29(6):115885
Comprehensive analysis of germline and somatic SDHA alterations reveals rare incidental germline variants and prognostic implications of somatic loss in breast cancer.41627790 · Butz, Henriett, Antal, Bálint, Papp, János et al.2026 · 0 citationsEndocrine-related cancer. 2026;33(2)
Insights from 2057 germline genetic tests in renal cell carcinoma patients support revisiting testing criteria.41507604 · Vibert, Roseline, El Baroudi, Yahya, Vecten, Maude et al.2026 · 2 citationsEuropean journal of human genetics : EJHG. 2026;34(3):421-428
Unbiased CRISPR Synthetic Lethal Screening for Genetic Vulnerabilities in Succinate Dehydrogenase (SDH)-loss Model of Paraganglioma.40909557 · Al Khazal, Fatimah J, Emch, Michael J, de Araujo Correia, Cristina M et al.2026 · 0 citationsbioRxiv : the preprint server for biology. 2025
Distinct proteomic and acylproteomic adaptations to succinate dehydrogenase loss in two cell contexts.40766370 · Zhou, Sherry X, Madden, Benjamin, Charlesworth, M Cristine et al.2025 · 1 citationbioRxiv : the preprint server for biology. 2025
Biomarkers Improving Genetic and Metastatic Disease Prediction in Paraganglioma: Insights From a Prospective Study.39541377 · Drossart, Tom, Buffet, Alexandre, Janbain, Ali et al.2025 · 14 citationsThe Journal of clinical endocrinology and metabolism. 2025;110(8):2193-2204
Altitude and paraganglioma.40339694 · Sanceau, Julie, Westbrook, Rebecca, Favier, Judith2025 · 5 citationsAnnales d'endocrinologie. 2025;86(3):101772
Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes.40199338 · Arenillas, Carlota, Celada, Lucía, Ruiz-Cantador, José et al.2025 · 13 citationsCancer discovery. 2025;15(5):1037-1062
Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells.40235395 · Al Khazal, Fatimah, Rahimi, Leili, Feng, Fan et al.2025 · 1 citationJournal of cell science. 2025;138(9)
Triggering tumorigenic signaling: Succinate dehydrogenase inhibitor (SDHi) fungicides induce oncometabolite accumulation and metabolic shift in human colon cells.40359599 · Duarte Hospital, Carolina, Tête, Arnaud, Debizet, Kloé et al.2025 · 7 citationsEnvironment international. 2025;199:109503
Similar deficiencies, different outcomes: succinate dehydrogenase loss in adrenal medulla vs. fibroblast cell culture models of paraganglioma.39716277 · Al Khazal, Fatimah J, Bhat, Sanjana Mahadev, Zhu, Yuxiang et al.2026 · 7 citationsCancer & metabolism. 2024;12(1):39
MAML3-fusions modulate vascular and immune tumour microenvironment and confer high metastatic risk in pheochromocytoma and paraganglioma.39218714 · Monteagudo, María, Calsina, Bruna, Salazar-Hidalgo, Milton E et al.2024 · 12 citationsBest practice & research. Clinical endocrinology & metabolism. 2024;38(6):101931
Advancements and challenges in pheochromocytoma and paraganglioma research: a collection of insights.38758683 · Favier, Judith, Pacak, Karel, Clifton-Bligh, Roderick2024 · 0 citationsEndocrine-related cancer. 2024;31(8)
EPAS1-mutated paragangliomas associated with haemoglobin disorders.38195958 · Mancini, Maxence, Buffet, Alexandre, Porte, Baptiste et al.2024 · 6 citationsBritish journal of haematology. 2024;204(3):1054-1060
Progress and challenges in experimental models for pheochromocytoma and paraganglioma.36810302 · Tischler, Arthur S, Favier, Judith2023 · 11 citationsEndocrine-related cancer. 2023;30(5)
New advances in endocrine hypertension: from genes to biomarkers.36646167 · Fernandes-Rosa, Fabio L, Boulkroun, Sheerazed, Fedlaoui, Bakhta et al.2023 · 27 citationsKidney international. 2023;103(3):485-500
SDHx mutation and pituitary adenoma: can in vivo 1H-MR spectroscopy unravel the link?36449569 · Branzoli, Francesca, Salgues, Betty, Marjańska, Małgorzata et al.2023 · 6 citationsEndocrine-related cancer. 2023;30(2)
Succinate Dehydrogenase, Succinate, and Superoxides: A Genetic, Epigenetic, Metabolic, Environmental Explosive Crossroad.35892689 · Bénit, Paule, Goncalves, Judith, El Khoury, Riyad et al.2024 · 48 citationsBiomedicines. 2022;10(8)
Preclinical evaluation of targeted therapies in Sdhb-mutated tumors.35348472 · Moog, Sophie, Salgues, Betty, Braik-Djellas, Yasmine et al.2022 · 12 citationsEndocrine-related cancer. 2022;29(6):375-388
Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched.35631574 · Feliz Morel, Álvaro Javier, Hasanovic, Anida, Morin, Aurélie et al.2022 · 5 citationsPharmaceutics. 2022;14(5)
[Succinate dehydrogenase in cancer].35333162 · Moog, Sophie, Favier, Judith2022 · 0 citationsMedecine sciences : M/S. 2022;38(3):255-262
Low-grade oncocytic renal tumor (LOT): mutations in mTOR pathway genes and low expression of FOXI1.34531523 · Morini, Aurélien, Drossart, Tom, Timsit, Marc-Olivier et al.2022 · 58 citationsModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2022;35(3):352-360
International initiative for a curated SDHB variant database improving the diagnosis of hereditary paraganglioma and pheochromocytoma.34452955 · Ben Aim, Laurene, Maher, Eamonn R, Cascon, Alberto et al.2022 · 12 citationsJournal of medical genetics. 2022;59(8):785-792
Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate.34127497 · Goncalves, Judith, Moog, Sophie, Morin, Aurélie et al.2021 · 67 citationsCancer research. 2021;81(13):3480-3494
Screening of a Large Cohort of Asymptomatic SDHx Mutation Carriers in Routine Practice.33247927 · Saie, Clotilde, Buffet, Alexandre, Abeillon, Juliette et al.2021 · 13 citationsThe Journal of clinical endocrinology and metabolism. 2021;106(3):e1301-e1315
Sunitinib-induced cardiac hypertrophy and the endothelin axis.33664864 · Sourdon, Joevin, Facchin, Caterina, Certain, Anaïs et al.2021 · 23 citationsTheranostics. 2021;11(8):3830-3838
Germline DLST Variants Promote Epigenetic Modifications in Pheochromocytoma-Paraganglioma.33180916 · Buffet, Alexandre, Zhang, Juan, Rebel, Heggert et al.2021 · 11 citationsThe Journal of clinical endocrinology and metabolism. 2021;106(2):459-471
An update on adult forms of hereditary pheochromocytomas and paragangliomas.33186184 · Dariane, Charles, Goncalves, Judith, Timsit, Marc-Olivier et al.2021 · 14 citationsCurrent opinion in oncology. 2021;33(1):23-32
Epigenetic and metabolic reprogramming of SDH-deficient paragangliomas.33112834 · Moog, Sophie, Lussey-Lepoutre, Charlotte, Favier, Judith2021 · 37 citationsEndocrine-related cancer. 2020;27(12):R451-R463
Overexpression of miR-483-5p is confined to metastases and linked to high circulating levels in patients with metastatic pheochromocytoma/paraganglioma.33377638 · Castro-Vega, Luis Jaime, Calsina, Bruna, Burnichon, Nelly et al.2021 · 11 citationsClinical and translational medicine. 2020;10(8):e260
TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition.32234487 · Morin, Aurélie, Goncalves, Judith, Moog, Sophie et al.2021 · 102 citationsCell reports. 2020;30(13):4551-4566.e7
[Pathologist contribution in the diagnosis of hereditary predisposition to paranganglioma and pheochromocytoma].32146049 · Broudin, Chloé, Favier, Judith, Verkarre, Virginie et al.2021 · 2 citationsAnnales de pathologie. 2020;40(2):134-141
Transcriptome Analysis of lncRNAs in Pheochromocytomas and Paragangliomas.31678991 · Job, Sylvie, Georges, Adrien, Burnichon, Nelly et al.2020 · 19 citationsThe Journal of clinical endocrinology and metabolism. 2020;105(3)
An overview of 20 years of genetic studies in pheochromocytoma and paraganglioma.32295730 · Buffet, Alexandre, Burnichon, Nelly, Favier, Judith et al.2020 · 190 citationsBest practice & research. Clinical endocrinology & metabolism. 2020;34(2):101416
Concurrent imaging of vascularization and metabolism in a mouse model of paraganglioma under anti-angiogenic treatment.32206105 · Facchin, Caterina, Perez-Liva, Mailyn, Garofalakis, Anikitos et al.2021 · 17 citationsTheranostics. 2020;10(8):3518-3532
Germline mutations in the new E1' cryptic exon of the VHL gene in patients with tumours of von Hippel-Lindau disease spectrum or with paraganglioma.31996412 · Buffet, Alexandre, Calsina, Bruna, Flores, Shahida et al.2021 · 20 citationsJournal of medical genetics. 2020;57(11):752-759
Succinate detection using in vivo 1H-MR spectroscopy identifies germline and somatic SDHx mutations in paragangliomas.31834447 · Lussey-Lepoutre, Charlotte, Bellucci, Alexandre, Burnichon, Nelly et al.2021 · 35 citationsEuropean journal of nuclear medicine and molecular imaging. 2020;47(6):1510-1517
Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function.31914648 · Kľučková, Katarína, Thakker, Alpesh, Vettore, Lisa et al.2020 · 35 citationsFASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020;34(1):303-315
Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells.31697708 · Bénit, Paule, Kahn, Agathe, Chretien, Dominique et al.2020 · 81 citationsPloS one. 2019;14(11):e0224132
Synergistic Highly Potent Targeted Drug Combinations in Different Pheochromocytoma Models Including Human Tumor Cultures.31322702 · Fankhauser, Maria, Bechmann, Nicole, Lauseker, Michael et al.2019 · 43 citationsEndocrinology. 2019;160(11):2600-2617
Carbonic anhydrase 9 immunohistochemistry as a tool to predict or validate germline and somatic VHL mutations in pheochromocytoma and paraganglioma-a retrospective and prospective study.31383958 · Favier, Judith, Meatchi, Tchao, Robidel, Estelle et al.2020 · 48 citationsModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2020;33(1):57-64
Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma.31410193 · Calsina, Bruna, Castro-Vega, Luis Jaime, Torres-Pérez, Rafael et al.2020 · 70 citationsTheranostics. 2019;9(17):4946-4958
Emerging molecular markers of metastatic pheochromocytomas and paragangliomas.31053249 · Goncalves, Judith, Lussey-Lepoutre, Charlotte, Favier, Judith et al.2019 · 21 citationsAnnales d'endocrinologie. 2019;80(3):159-162
Positive Impact of Genetic Test on the Management and Outcome of Patients With Paraganglioma and/or Pheochromocytoma.30698717 · Buffet, Alexandre, Ben Aim, Laurène, Leboulleux, Sophie et al.2020 · 131 citationsThe Journal of clinical endocrinology and metabolism. 2019;104(4):1109-1118
Targeted next-generation sequencing detects rare genetic events in pheochromocytoma and paraganglioma.30877234 · Ben Aim, Laurène, Pigny, Pascal, Castro-Vega, Luis Jaime et al.2020 · 83 citationsJournal of medical genetics. 2019;56(8):513-520
Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma.30301828 · Job, Sylvie, Draskovic, Irena, Burnichon, Nelly et al.2020 · 134 citationsClinical cancer research : an official journal of the American Association for Cancer Research. 2019;25(2):760-770
Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients.30008476 · Calsina, Bruna, Currás-Freixes, Maria, Buffet, Alexandre et al.2019 · 69 citationsGenetics in medicine : official journal of the American College of Medical Genetics. 2018;20(12):1652-1662
A new threat identified in the use of SDHIs pesticides targeting the mitochondrial succinate dehydrogenase enzyme10.1101/289058v2 · Benit, P., Bortoli, S., Huc, L. et al.2018 · 8 citationsbioRxiv
Rodent models of pheochromocytoma, parallels in rodent and human tumorigenesis.29427052 · Lussey-Lepoutre, Charlotte, Buffet, Alexandre, Morin, Aurélie et al.2018 · 21 citationsCell and tissue research. 2018;372(2):379-392
Career total: 204 works. 117 are in this corpus.Showing the 50 most recent.
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