LM
Lena Maier-Hein
cs.CVcs.LGeess.IVSurgical data scienceAlgorithmsphysics.med-phDeep learningArtificial Intelligencecs.AIArtificial intelligence
On Valency
published · living versionsW_z8wecm87·v1 · currentpublished
A large annotated medical image dataset for the development and evaluation of segmentation algorithms
with Amber L. Simpson, Michela Antonelli, Spyridon Bakas, Michel Bilello +19
1 version
Preprints & journals
206 papers in the corpus · 2002–2026Performance uncertainty in medical image analysis: A large-scale investigation of confidence intervals.42887473 · André, Pascaline, Heitz, Charles, Christodoulou, Evangelia et al.2026 · 3 citationsMedical image analysis. 2026;116:104349
ManUSPECTRAL - the Mannheim Urology HyperSPECTRAL Imaging Atlas of 17 Physiological Human Organs.42844699 · Rathenborg, Alexander, Klütz, Vera, Grützner, Paula et al.2026 · 0 citationsBJU international. 2026
Federated Learning for surgical vision in appendicitis classification: Results of the FedSurg EndoVis 2024 challenge.42715718 · Kirchner, Max, Hoffmann, Hanna, Jenke, Alexander C et al.2026 · 1 citationMedical image analysis. 2027;115:104290
Reply to: Surgical scene understanding and the emerging challenge of independent validation in an industry-led AI ecosystem.42575930 · Carstens, Matthias, Vasisht, Shubha, Zhang, Zheyuan et al.2026 · 0 citationsNPJ digital medicine. 2026;9(1)
Photoacoustic device fingerprints induce bias in deep learning models.42288533 · Bender, Christoph J, Knopp, Marcel, Holzwarth, Niklas et al.2026 · 2 citationsScientific reports. 2026;16(1)
Current validation practice undermines surgical AI development.42078503 · Reinke, Annika, Li, Ziying O, Tizabi, Minu D et al.2026 · 1 citationArXiv. 2026
Development and validation of a machine learning model for community-based tuberculosis screening among persons aged ≥ 15 years in South Africa and Zambia.41959816 · Zimmer, Alexandra J, Muchie, Kindie Fentahun, Loharja, Henry et al.2026 · 0 citationsmedRxiv : the preprint server for health sciences. 2026
A multi-center analysis of deep learning methods for video polyp detection and segmentation2603.04288v2 · Noha Ghatwary, Pedro Chavarias Solano, Mohamed Ramzy Ibrahim et al.2026 · 0 citationsarXiv
Erratum: Learning to simulate realistic human diffuse reflectance spectra (Erratum).41924335 · Hübner, Marco, Bin Qasim, Ahmad, Studier-Fischer, Alexander et al.2026 · 0 citationsJournal of biomedical optics. 2026;31(3):039801
Learning to simulate realistic human diffuse reflectance spectra.41769154 · Hübner, Marco, Bin Qasim, Ahmad, Studier-Fischer, Alexander et al.2026 · 0 citationsJournal of biomedical optics. 2026;31(2):026004
Xeno-learning: knowledge transfer across species in deep learning-based spectral image analysis.41588072 · Sellner, Jan, Studier-Fischer, Alexander, Qasim, Ahmad Bin et al.2026 · 5 citationsNature biomedical engineering. 2026;10(8):1770-1784
Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge.41564633 · Rueckert, Tobias, Rauber, David, Maerkl, Raphaela et al.2026 · 7 citationsMedical image analysis. 2026;109:103945
Medical Imaging AI Competitions Lack Fairness2512.17581v2 · Annika Reinke, Evangelia Christodoulou, Sthuthi Sadananda et al.2025 · 1 citationarXiv
Including AI in diffusion-weighted breast MRI has potential to increase reader confidence and reduce workload.40985463 · Bounias, Dimitrios, Simons, Lina, Baumgartner, Michael et al.2025 · 0 citationsJournal of the American Medical Informatics Association : JAMIA. 2025;32(12):1908-1915
AI-driven preoperative risk assessment in kidney cancer surgery: A comparative feasibility study of machine learning models.41018917 · Mühlbauer, Julia, Gottstein, Luise, Egen, Luisa et al.2025 · 2 citationsBJUI compass. 2025;6(10):e70080
Comprehensive assessment of endothelial dysfunction before cellular therapy: EASIX, local imaging, and systemic biomarkers.41334245 · Simons, Laura, Alasfar, Lina, Qadoura, Muath et al.2025 · 10 citationsBlood vessels, thrombosis & hemostasis. 2025;2(4):100105
Advancing standards in biomedical image analysis validation: A perspective on Metrics Reloaded.40887841 · Reinke, Annika, Tizabi, Minu D, Maier-Hein, Lena2025 · 1 citationClinical and translational medicine. 2025;15(9):e70237
AI-powered skin spectral imaging enables instant sepsis diagnosis and outcome prediction in critically ill patients.40680113 · Seidlitz, Silvia, Hölzl, Katharina, von Garrel, Ayca et al.2025 · 18 citationsScience advances. 2025;11(29):eadw1968
Artificial Intelligence for Surgical Scene Understanding: A Systematic Review and Reporting Quality Meta-Analysis.40791708 · Carstens, Matthias, Vasisht, Shubha, Zhang, Zheyuan et al.2025 · 31 citationsmedRxiv : the preprint server for health sciences. 2025
Hyperspectral Imaging Accurately Detects Renal Malperfusion Due to High Intrarenal Pressure.40688377 · Egen, Luisa, Hommel, Moritz, Haney, Caelan Max et al.2025 · 1 citationEuropean urology open science. 2025;78:16-27
Anthropomorphic tissue-mimicking phantoms for oximetry validation in multispectral optical imaging.40678081 · Dreher, Kris K, Gröhl, Janek, Grace, Friso et al.2025 · 3 citationsJournal of biomedical optics. 2025;30(7):076006
TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods: a Korean translation.40739973 · Collins, Gary S, Moons, Karel G M, Dhiman, Paula et al.2025 · 13 citationsEwha medical journal. 2025;48(3):e48
Challenging Vision-Language Models with Surgical Data: A New Dataset and Broad Benchmarking Study2506.06232v2 · Leon Mayer, Tim Radsch, Dominik Michael et al.2025 · 0 citationsarXiv
Photoacoustic imaging for monitoring radiotherapy treatment response in head and neck tumors.40348865 · Holzwarth, Niklas, Rachel, Zoe, Nölke, Jan-Hinrich et al.2025 · 6 citationsScientific reports. 2025;15(1):16344
Shortcut learning leads to sex bias in deep learning models for photoacoustic tomography.40343639 · Knopp, Marcel, Bender, Christoph J, Holzwarth, Niklas et al.2025 · 5 citationsInternational journal of computer assisted radiology and surgery. 2025;20(7):1325-1333
CARL: Camera-Agnostic Representation Learning for Spectral Image Analysis2504.19223v4 · Alexander Baumann, Leonardo Ayala, Silvia Seidlitz et al.2025 · 0 citationsarXiv
Semantic hyperspectral image synthesis for cross-modality knowledge transfer in surgical data science.40274718 · Tran Ba, Viet, Hübner, Marco, Bin Qasim, Ahmad et al.2025 · 1 citationInternational journal of computer assisted radiology and surgery. 2025;20(6):1205-1213
PROBAST+AI: an updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods.40127903 · Moons, Karel G M, Damen, Johanna A A, Kaul, Tabea et al.2025 · 957 citationsBMJ (Clinical research ed.). 2025;388:e082505
Bridging vision language model (VLM) evaluation gaps with a framework for scalable and cost-effective benchmark generation2502.15563v1 · Tim Radsch, Leon Mayer, Simon Pavicic et al.2025 · 0 citationsarXiv
FUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare.39909534 · Lekadir, Karim, Frangi, Alejandro F, Porras, Antonio R et al.2026 · 771 citationsBMJ (Clinical research ed.). 2025;388:e081554
Beyond Knowledge Silos: Task Fingerprinting for Democratization of Medical Imaging AI2412.08763v2 · Patrick Godau, Akriti Srivastava, Constantin Ulrich et al.2024 · 1 citationarXiv
SURE-VQA: Systematic Understanding of Robustness Evaluation in Medical VQA Tasks2411.19688v3 · Kim-Celine Kahl, Selen Erkan, Jeremias Traub et al.2024 · 0 citationsarXiv
An objective comparison of methods for augmented reality in laparoscopic liver resection by preoperative-to-intraoperative image fusion from the MICCAI2022 challenge.39488186 · Ali, Sharib, Espinel, Yamid, Jin, Yueming et al.2024 · 51 citationsMedical image analysis. 2025;99:103371
Aliado - A design concept of AI for decision support in oncological liver surgery.39362815 · Schulze, A, Haselbeck-Köbler, M, Brandenburg, J M et al.2025 · 6 citationsEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2025;51(7):108669
Photoacoustic Quantification of Tissue Oxygenation Using Conditional Invertible Neural Networks.38787678 · Nolke, Jan-Hinrich, Adler, Tim J, Schellenberg, Melanie et al.2024 · 11 citationsIEEE transactions on medical imaging. 2024;43(9):3366-3376
Handling Geometric Domain Shifts in Semantic Segmentation of Surgical RGB and Hyperspectral Images2408.15373v1 · Silvia Seidlitz, Jan Sellner, Alexander Studier-Fischer et al.2024 · 1 citationarXiv
Spectral characterization of intraoperative renal perfusion using hyperspectral imaging and artificial intelligence.39068299 · Studier-Fischer, A, Bressan, M, Qasim, A Bin et al.2024 · 20 citationsScientific reports. 2024;14(1):17262
Quality Assured: Rethinking Annotation Strategies in Imaging AI2407.17596v2 · Tim Radsch, Annika Reinke, Vivienn Weru et al.2024 · 9 citationsarXiv
Overcoming Common Flaws in the Evaluation of Selective Classification Systems2407.01032v2 · Jeremias Traub, Till J. Bungert, Carsten T. Luth et al.2024 · 11 citationsarXiv
Miniaturized electromagnetic tracking enables efficient ultrasound-navigated needle insertions.38898086 · Seitel, Alexander, Groener, Daniel, Eisenmann, Matthias et al.2024 · 8 citationsScientific reports. 2024;14(1):14161
A surgical activity model of laparoscopic cholecystectomy for co-operation with collaborative robots.38872018 · Younis, R, Yamlahi, A, Bodenstedt, S et al.2024 · 13 citationsSurgical endoscopy. 2024;38(8):4316-4328
The SPECTRAL Perfusion Arm Clamping dAtaset (SPECTRALPACA) for video-rate functional imaging of the skin.38796545 · Ayala, Leonardo, Mindroc-Filimon, Diana, Rees, Maike et al.2024 · 5 citationsScientific data. 2024;11(1):536
TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods.38626948 · Collins, Gary S, Moons, Karel G M, Dhiman, Paula et al.2024 · 4,333 citationsBMJ (Clinical research ed.). 2024;385:e078378
Depth-Specific Hypoxic Responses to Spreading Depolarizations in Gyrencephalic Swine Cortex Unveiled by Photoacoustic Imaging.38622426 · Santos, Edgar, Lopez-Navarro, Juan M, Suarez-Gutierrez, Marcos Alejandro et al.2025 · 5 citationsTranslational stroke research. 2025;16(3):672-678
FISBe: A real-world benchmark dataset for instance segmentation of long-range thin filamentous structures2404.00130v1 · Lisa Mais, Peter Hirsch, Claire Managan et al.2024 · 3 citationsarXiv
Test-time augmentation with synthetic data addresses distribution shifts in spectral imaging.38483702 · Qasim, Ahmad Bin, Motta, Alessandro, Studier-Fischer, Alexander et al.2024 · 4 citationsInternational journal of computer assisted radiology and surgery. 2024;19(6):1021-1031
Understanding metric-related pitfalls in image analysis validation.36945687 · Reinke, Annika, Tizabi, Minu D, Baumgartner, Michael et al.2025 · 233 citationsArXiv. 2024
Correction: Comparison of Four Active SARS-CoV-2 Surveillance Strategies in Representative Population Sample Points: Two-Factor Factorial Randomized Controlled Trial.38364221 · Deckert, Andreas, Anders, Simon, Morales, Ivonne et al.2024 · 0 citationsJMIR public health and surveillance. 2024;10:e57203
Metrics reloaded: recommendations for image analysis validation.38347141 · Maier-Hein, Lena, Reinke, Annika, Godau, Patrick et al.2024 · 539 citationsNature methods. 2024;21(2):195-212
An objective comparison of methods for augmented reality in laparoscopic liver resection by preoperative-to-intraoperative image fusion2401.15753v2 · Sharib Ali, Yamid Espinel, Yueming Jin et al.2024 · 2 citationsarXiv
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