TR
Thomas Rulicke
miceAnimals, Genetically ModifiedGene Transfer TechniquesMiceLeukemia, Myelogenous, Chronic, BCR-ABL PositiveneuroscienceAnimal WelfareDisease Models, AnimalDNA Transposable ElementsMice, Knockout
On Valency
published · living versionsW_fgs3n2ts·v1 · currentpublished
Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism
with Iain G. Johnston, Joerg P. Burgstaller, Vitezslav Havlicek, Thomas Kolbe +3
1 version
Preprints & journals
218 papers in the corpus · 1991–2025STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts.41405992 · Dennaoui, Rayane, Wicker, Madison N, Moen, Carson et al.2026 · 0 citationsCell reports. 2026;45(1):116703
Quantitative Proteomics Identifies Potential Molecular Adaptations in Mouse Models of Congenital Stationary Night Blindness Type 2.41224078 · Ganglberger, Matthias, Zanetti, Lucia, Egger, Anna-Sophia et al.2025 · 0 citationsMolecular & cellular proteomics : MCP. 2025;24(12):101462
The receptor BLT1 is essential on neutrophils in a mouse model of mucous membrane pemphigoid.40985889 · Bremer, Tabea, Murthy, Sripriya, Patzelt, Sabrina et al.2025 · 3 citationsJCI insight. 2025;10(18)
Accelerated Endosomal Escape of Splice-Switching Oligonucleotides Enables Efficient Hepatic Splice Correction.39873730 · Weiss, Silvia, Decker, Simon, Kugler, Christoph et al.2025 · 4 citationsACS applied materials & interfaces. 2025;17(6):9000-9018
A simple method for repeated in vivo sperm collection from laboratory mice.39017771 · Burgstaller, Sophie M, Auer, Kerstin E, Rülicke, Thomas2024 · 0 citationsJournal of assisted reproduction and genetics. 2024;41(9):2537-2546
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia.38498036 · Klein, Klara, Kollmann, Sebastian, Hiesinger, Angela et al.2024 · 7 citationsBlood. 2024;143(24):2474-2489
Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice.38857283 · Burnett, Laura E, Koppensteiner, Peter, Symonova, Olga et al.2024 · 1 citationPLoS biology. 2024;22(6):e3002668
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.38618957 · Suske, Tobias, Sorger, Helena, Manhart, Gabriele et al.2024 · 13 citationsThe Journal of clinical investigation. 2024;134(8)
Effects of Tulp4 deficiency on murine embryonic development and adult phenotype.38115643 · Jäger, Roland, Geyer, Stefan H, Kavirayani, Anoop et al.2024 · 2 citationsMicroscopy research and technique. 2024;87(4):854-866
C-type lectin receptor expression is a hallmark of neutrophils infiltrating the skin in epidermolysis bullosa acquisita.37799716 · Guerrero-Juarez, Christian F, Schilf, Paul, Li, Jing et al.2023 · 13 citationsFrontiers in immunology. 2023;14:1266359
Inducible overexpression of a FAM3C/ILEI transgene has pleiotropic effects with shortened life span, liver fibrosis and anemia in mice.37713409 · Schmidt, Ulrike, Uluca, Betül, Vokic, Iva et al.2023 · 4 citationsPloS one. 2023;18(9):e0286256
Vienna Cancer Stem Cell Club (VCSCC): 20 year jubilee and future perspectives.37493441 · Valent, Peter, Sadovnik, Irina, Peter, Barbara et al.2023 · 1 citationExpert review of hematology. 2023;16(9):659-670
Mate genetic similarity affects mating behaviour but not maternal investment in mice.37386286 · Auer, Kerstin E, Primus, Jasmin, Istel, Sonja et al.2023 · 2 citationsScientific reports. 2023;13(1):10536
The impact of percutaneous epididymal sperm aspiration on sperm quality in mice.37227214 · Windhofer, Lisa, Boersma, Auke, Dahlhoff, Maik et al.2023 · 3 citationsReproduction & fertility. 2023;4(2)
Large neutral amino acid levels tune perinatal neuronal excitability and survival.36996814 · Knaus, Lisa S, Basilico, Bernadette, Malzl, Daniel et al.2023 · 70 citationsCell. 2023;186(9):1950-1967.e25
Engraftment in NSGSCF mice correlates with the WHO category and prognosis in systemic mastocytosis.36918646 · Willmann, Michael, Peter, Barbara, Slavnitsch, Katharina et al.2023 · 0 citationsLeukemia. 2023;37(5):1162-1165
Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.37025950 · Imre, Gergely, Takács, Bertalan, Czipa, Erik et al.2023 · 10 citationsMolecular therapy. Methods & clinical development. 2023;29:145-159
Phenotypic characterization of disease-initiating stem cells in JAK2- or CALR-mutated myeloproliferative neoplasms.36814396 · Ivanov, Daniel, Milosevic Feenstra, Jelena D, Sadovnik, Irina et al.2023 · 14 citationsAmerican journal of hematology. 2023;98(5):770-783
Comparison of unilateral and bilateral embryo transfer in mice.36734260 · Auer, Kerstin E, Kolbe, Thomas, Laschalt, Claudia et al.2023 · 1 citationLaboratory animals. 2023;57(4):424-431
Correction: WDFY3 mutation alters laminar position and morphology of cortical neurons.36721238 · Schaaf, Zachary A, Tat, Lyvin, Cannizzaro, Noemi et al.2023 · 0 citationsMolecular autism. 2023;14(1):4
Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged Mice.36754207 · Qian, Hui, Chao, Xiaojuan, Wang, Shaogui et al.2023 · 18 citationsCellular and molecular gastroenterology and hepatology. 2023;15(5):1027-1049
STAT5 Gain-of-Function Variants Promote Precursor T-Cell Receptor Activation to Drive T-Cell Acute Lymphoblastic Leukemia10.1101/2022.12.21.519945v1 · Suske, T., Sorger, H., Ruge, F. et al.2022 · 1 citationbioRxiv
Recurrent impairments in visual perception and place avoidance across autism models are causally linked in the haploinsufficiency model of intellectual disability Setd510.1101/2022.10.11.511691v4 · Burnett, L. E., Koppensteiner, P., Symonova, O. et al.2022 · 2 citationsbioRxiv
The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression.36110849 · Hutter, Katharina, Rülicke, Thomas, Szabo, Tamas G et al.2022 · 19 citationsFrontiers in immunology. 2022;13:967914
Effect of Different Ambient Temperatures on Reproductive Outcome and Stress Level of Lactating Females in Two Mouse Strains.36009730 · Kolbe, Thomas, Lassnig, Caroline, Poelzl, Andrea et al.2022 · 8 citationsAnimals : an open access journal from MDPI. 2022;12(16)
Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT.36052260 · Aboouf, Mostafa A, Guscetti, Franco, von Büren, Nadine et al.2022 · 7 citationsFrontiers in oncology. 2022;12:976961
Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice.35919386 · Boersma, Auke, Primus, Jasmin, Wagner, Bettina et al.2023 · 12 citationsReproductive medicine and biology. 2022;21(1):e12480
BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph+ chronic myeloid leukemia.35794848 · Peter, Barbara, Eisenwort, Gregor, Sadovnik, Irina et al.2022 · 27 citationsAmerican journal of hematology. 2022;97(9):1215-1225
Tissue-Wide Effects Override Cell-Intrinsic Gene Function in Radial Neuron Migration.38596707 · Hansen, Andi H, Pauler, Florian M, Riedl, Michael et al.2024 · 10 citationsOxford open neuroscience. 2022;1:kvac009
WDFY3 mutation alters laminar position and morphology of cortical neurons.35733184 · Schaaf, Zachary A, Tat, Lyvin, Cannizzaro, Noemi et al.2022 · 10 citationsMolecular autism. 2022;13(1):27
The miR-26 family regulates early B cell development and transformation.35459737 · Hutter, Katharina, Lindner, Silke E, Kurschat, Constanze et al.2022 · 10 citationsLife science alliance. 2022;5(8)
KappaBle fluorescent reporter mice enable low-background single-cell detection of NF-κB transcriptional activity in vivo.35589985 · Tortola, Luigi, Piattini, Federica, Hausmann, Annika et al.2022 · 4 citationsMucosal immunology. 2022;15(4):656-667
Tissue-wide Effects Overrule Cell-intrinsic Gene Function in Cortical Projection Neuron Migration10.1101/2022.02.16.480659v1 · Hansen, A. H., Pauler, F. M., Riedl, M. et al.2022 · 1 citationbioRxiv
Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis.35150895 · Korbelius, Melanie, Vujić, Nemanja, Kuentzel, Katharina B et al.2022 · 7 citationsBiochimica et biophysica acta. Molecular and cell biology of lipids. 2022;1867(4):159121
Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy.34710483 · Chao, Xiaojuan, Wang, Shaogui, Fulte, Sam et al.2022 · 69 citationsJournal of hepatology. 2022;76(3):639-651
Effect of different ambient temperatures on reproductive outcome and wellbeing of lactating females in two mouse strains10.1101/2021.10.15.464536v1 · Kolbe, T., Lassnig, C., Poelzl, A. et al.2021 · 0 citationsbioRxiv
KappaBle fluorescent reporter mice enable dynamic and low-background single-cell detection of NF-kB activity in vivo10.1101/2021.09.02.458704v1 · Tortola, L., Ampenberger, F., Rosenwald, E. et al.2021 · 1 citationbioRxiv
Different Roles of p62 (SQSTM1) Isoforms in Keratin-Related Protein Aggregation.34207662 · Somlapura, Meghana, Gottschalk, Benjamin, Lahiri, Pooja et al.2021 · 16 citationsInternational journal of molecular sciences. 2021;22(12)
Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia.33785864 · Eisenwort, Gregor, Sadovnik, Irina, Keller, Alexandra et al.2021 · 19 citationsLeukemia. 2021;35(11):3176-3187
GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells.33352118 · Takeo, Yukari H, Shuster, S Andrew, Jiang, Linnie et al.2021 · 52 citationsNeuron. 2021;109(4):629-644.e8
Delineation of target expression profiles in CD34+/CD38- and CD34+/CD38+ stem and progenitor cells in AML and CML.33085758 · Herrmann, Harald, Sadovnik, Irina, Eisenwort, Gregor et al.2021 · 108 citationsBlood advances. 2020;4(20):5118-5132
Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis.32705746 · Hutter, Katharina, Rülicke, Thomas, Drach, Mathias et al.2021 · 19 citationsThe FEBS journal. 2021;288(5):1533-1545
GluD2- and Cbln1-mediated Competitive Synaptogenesis Shapes the Dendritic Arbors of Cerebellar Purkinje Cells10.1101/2020.06.14.151258v1 · Takeo, Y. H., Shuster, A., Jiang, L. et al.2020 · 2 citationsbioRxiv
A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis10.1101/2020.06.05.136192v1 · Contreras, X., Davaatseren, A., Amberg, N. et al.2020 · 73 citationsbioRxiv
Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.31166588 · Kolleritsch, Stephanie, Kien, Benedikt, Schoiswohl, Gabriele et al.2020 · 54 citationsCardiovascular research. 2020;116(2):339-352
Corrigendum to High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype12 [Translational Oncology Volume 12, Issue 2, February 2019, Pages 256-268].32081369 · Golob-Schwarzl, N, Bettermann, K, Mehta, A K et al.2020 · 0 citationsTranslational oncology. 2020;13(2):490-492
Measurement of Fecal Testosterone Metabolites in Mice: Replacement of Invasive Techniques.31963733 · Auer, Kerstin E, Kußmaul, Marius, Möstl, Erich et al.2020 · 31 citationsAnimals : an open access journal from MDPI. 2020;10(1)
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.31123029 · Maurer, Barbara, Nivarthi, Harini, Wingelhofer, Bettina et al.2021 · 46 citationsHaematologica. 2020;105(2):435-447
Loss of Ing3 Expression Results in Growth Retardation and Embryonic Death.31905726 · Fink, Dieter, Yau, Tienyin, Nabbi, Arash et al.2020 · 21 citationsCancers. 2019;12(1)
Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice.31806023 · Moschinger, Michael, Hilse, Karolina E, Rupprecht, Anne et al.2020 · 18 citationsBiology of sex differences. 2019;10(1):56
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