AK
Annette Kopp-Schneider
cs.CVModels, BiologicalModels, StatisticalPositron Emission Tomography Computed TomographyMetastatic melanomaResearch DesignFluorodeoxyglucose F18Melanoma[18F]FDG PET/CTAlgorithms
On Valency
published · living versionsW_z8wecm87·v1 · currentpublished
A large annotated medical image dataset for the development and evaluation of segmentation algorithms
with Amber L. Simpson, Michela Antonelli, Spyridon Bakas, Michel Bilello +19
1 version
Preprints & journals
268 papers in the corpus · 1991–2026Cancer co-medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care.42773858 · Degen, Miriam, Kopp-Schneider, Annette, Vlaski, Tomislav et al.2026 · 0 citationsJournal of internal medicine. 2026
Corrigendum to "Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review" [Environ. Int. 199 (2025) 109482].42442967 · Mevissen, Meike, Ducray, Angélique, Ward, Jerrold M et al.2026 · 0 citationsEnvironment international. 2026;214:110368
Correction: Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis.42315827 · Fankhauser, Laura, Ligas, Franca, Lesa, Giovanni et al.2026 · 0 citationsPharmaceutical medicine. 2026;40(4):325
Tree-based exploratory identification of predictive biomarkers in non-randomized data.42365268 · Krzykalla, Julia, Saadati, Maral, Hielscher, Wiebke et al.2026 · 0 citationsBMC medical research methodology. 2026;26(1)
Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis.42332879 · Böhnlein, Jonas, Maass, Johann G, Dennig, Julia et al.2026 · 0 citationsHGG advances. 2026;7(4):100636
Interpreting [18F]FDG-avid fractures after induction therapy in multiple myeloma: insights from the PET/CT sub-study of the Phase 3 GMMG-HD7 trial.42234005 · Sachpekidis, Christos, Hajiyianni, Marina, Wennmann, Markus et al.2026 · 0 citationsEuropean journal of nuclear medicine and molecular imaging. 2026;53(11):6605-6609
Beyond target lesions: Prognostic value of longitudinal AI-derived whole-body [1⁸F]FDG PET/CT metrics in metastatic melanoma.42189229 · Sachpekidis, Christos, Vagenas, Theodoros P, Müller, Marilena et al.2026 · 1 citationEuropean journal of nuclear medicine and molecular imaging. 2026;53(10):5907-5920
Paediatric Phase I/II Clinical Trial Assessments Under the New EU Clinical Trial Regulation: A Descriptive Analysis.42081189 · Fankhauser, Laura, Ligas, Franca, Lesa, Giovanni et al.2026 · 0 citationsPharmaceutical medicine. 2026;40(3):209-223
Protocol of the LEONORA randomized clinical trial: Lower gastrointestinal symptom burden by prophylaxis with synbiotics after colorectal cancer surgery.41882573 · Schöttker, Ben, Kopp-Schneider, Annette, Biehl, Lena2026 · 0 citationsBMC cancer. 2026;26(1)
Simple, robust and near optimal designs for the estimation of log-logistic dose response functions.41807795 · Holland-Letz, Tim, Kopp-Schneider, Annette2026 · 0 citationsArchives of toxicology. 2026;100(6):2451-2465
Too rare to be random: genetic finding suggests previously unrecognized path of mutagenesis10.64898/2026.03.03.26346966v1 · Boehnlein, J., Maass, J. G., Dennig, J. et al.2026 · 0 citationsmedRxiv
Early-detection and prevention effects of screening sigmoidoscopy: evidence from randomized trials revisited.41165595 · Brenner, Hermann, Holland-Letz, Tim, Kopp-Schneider, Annette et al.2026 · 2 citationsJournal of the National Cancer Institute. 2026;118(3):422-428
Xeno-learning: knowledge transfer across species in deep learning-based spectral image analysis.41588072 · Sellner, Jan, Studier-Fischer, Alexander, Qasim, Ahmad Bin et al.2026 · 5 citationsNature biomedical engineering. 2026;10(8):1770-1784
Erratum to: Detection of myeloma-associated osteolytic bone lesions with energy-integrating and photon-counting detector CT.41528427 · Grözinger, Martin, Wennmann, Markus, Sawall, Stefan et al.2026 · 0 citationsRadiologie (Heidelberg, Germany). 2026
Methodologically solid and analytically rigorous: the evaluations of our systematic review on RF-EMF and animal cancer are reliable.41372002 · Mevissen, Meike, Ducray, Angélique, Ward, Jerrold M et al.2026 · 1 citationEnvironment international. 2026;207:109962
Variable Selection via Fused Sparse-Group Lasso Penalized Multi-state Models Incorporating Molecular Data.41146443 · Miah, Kaya, Goeman, Jelle J, Putter, Hein et al.2025 · 2 citationsBiometrical journal. Biometrische Zeitschrift. 2025;67(6):e70087
From Data to Knowledge. Advancing Life Sciences: Editorial for the CEN2023 Special Issue.40960010 · Brannath, Werner, Bretz, Frank, Burger, Hans Ulrich et al.2025 · 0 citationsBiometrical journal. Biometrische Zeitschrift. 2025;67(5):e70077
Validation of novel low-dose CT methods for quantifying bone marrow in the appendicular skeleton of patients with multiple myeloma: initial results from the [18F]FDG PET/CT sub-study of the Phase 3 GMMG-HD7 Trial.41032077 · Sachpekidis, Christos, Hajiyianni, Marina, Grözinger, Martin et al.2026 · 4 citationsEuropean journal of nuclear medicine and molecular imaging. 2026;53(3):1509-1520
Artificial intelligence-assisted assessment of metabolic response to tebentafusp in metastatic uveal melanoma: a long axial field-of-view [18F]FDG PET/CT study.40913640 · Sachpekidis, Christos, Machiraju, Devayani, Strauss, Dimitrios Stefanos et al.2026 · 4 citationsEuropean journal of nuclear medicine and molecular imaging. 2026;53(3):1570-1580
Principled type I error rate inflation in two-arm clinical trial designs with external control information borrowing2508.16348v2 · Silvia Calderazzo, Manuel Wiesenfarth, Vivienn Weru et al.2025 · 0 citationsarXiv
Targeted therapy for rare BRAF-mutated melanoma: Updated multicenter analysis and launch of a publicly accessible online outcome database.40850313 · Menzer, Christian, Dugas-Breit, Susanne, Dugas, Martin et al.2025 · 5 citationsEuropean journal of cancer (Oxford, England : 1990). 2025;228:115703
Correction to: Artificial intelligence-based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma.39984746 · Sachpekidis, Christos, Enqvist, Olof, Ulén, Johannes et al.2026 · 0 citationsEuropean journal of nuclear medicine and molecular imaging. 2025;52(8):2746-2748
Photoacoustic imaging for monitoring radiotherapy treatment response in head and neck tumors.40348865 · Holzwarth, Niklas, Rachel, Zoe, Nölke, Jan-Hinrich et al.2025 · 6 citationsScientific reports. 2025;15(1):16344
False Promises in Medical Imaging AI? Assessing Validity of Outperformance Claims2505.04720v2 · Evangelia Christodoulou, Annika Reinke, Pascaline Andre et al.2025 · 2 citationsarXiv
Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review.40339346 · Mevissen, Meike, Ducray, Angélique, Ward, Jerrold M et al.2025 · 31 citationsEnvironment international. 2025;199:109482
Clonal hematopoiesis landscape in frequent blood donors.40067117 · Karpova, Darja, Huerga Encabo, Hector, Donato, Elisa et al.2025 · 10 citationsBlood. 2025;145(21):2411-2423
Unraveling the effects of screening colonoscopy on colorectal cancer early detection and prevention: the NordICC trial revisited.39679861 · Brenner, Hermann, Holland-Letz, Tim, Kopp-Schneider, Annette et al.2025 · 9 citationsCancer communications (London, England). 2025;45(3):205-208
Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior2412.03185v2 · Vivienn Weru, Annette Kopp-Schneider, Manuel Wiesenfarth et al.2024 · 0 citationsarXiv
Confidence intervals uncovered: Are we ready for real-world medical imaging AI?2409.17763v2 · Evangelia Christodoulou, Annika Reinke, Rola Houhou et al.2024 · 12 citationsarXiv
Quality Assured: Rethinking Annotation Strategies in Imaging AI2407.17596v2 · Tim Radsch, Annika Reinke, Vivienn Weru et al.2024 · 9 citationsarXiv
Detection of myeloma-associated osteolytic bone lesions with energy-integrating and photon-counting detector CT.39020050 · Grözinger, Martin, Wennmann, Markus, Sawall, Stefan et al.2024 · 1 citationRadiologie (Heidelberg, Germany). 2024;64(Suppl 1):24-31
The German sickle cell disease registry reveals a surprising risk of acute splenic sequestration and an increased transfusion requirement in patients with compound heterozygous sickle cell disease HbS/β-thalassaemia and no or low HbA expression.38946051 · Allard, Pierre, Tagliaferri, Laura, Weru, Vivienn et al.2024 · 4 citationsEuropean journal of haematology. 2024;113(4):501-509
Artificial intelligence-based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma.38456971 · Sachpekidis, Christos, Enqvist, Olof, Ulén, Johannes et al.2024 · 34 citationsEuropean journal of nuclear medicine and molecular imaging. 2024;51(8):2293-2307
Understanding metric-related pitfalls in image analysis validation.36945687 · Reinke, Annika, Tizabi, Minu D, Baumgartner, Michael et al.2025 · 233 citationsArXiv. 2024
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II.38327081 · Pepić, Amra, Stark, Maria, Friede, Tim et al.2024 · 2 citationsStatistical methods in medical research. 2024;33(3):433-448
Metrics reloaded: recommendations for image analysis validation.38347141 · Maier-Hein, Lena, Reinke, Annika, Godau, Patrick et al.2024 · 539 citationsNature methods. 2024;21(2):195-212
Robust incorporation of historical information with known type I error rate inflation.38063813 · Calderazzo, Silvia, Wiesenfarth, Manuel, Kopp-Schneider, Annette2024 · 4 citationsBiometrical journal. Biometrische Zeitschrift. 2024;66(1):e2200322
Simulating and reporting frequentist operating characteristics of clinical trials that borrow external information: Towards a fair comparison in case of one-arm and hybrid control two-arm trials.37632266 · Kopp-Schneider, Annette, Wiesenfarth, Manuel, Held, Leonhard et al.2024 · 7 citationsPharmaceutical statistics. 2024;23(1):4-19
Application of an artificial intelligence-based tool in [18F]FDG PET/CT for the assessment of bone marrow involvement in multiple myeloma.37493665 · Sachpekidis, Christos, Enqvist, Olof, Ulén, Johannes et al.2023 · 34 citationsEuropean journal of nuclear medicine and molecular imaging. 2023;50(12):3697-3708
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.37495107 · Nůsková, Hana, Cortizo, Fabiola Garcia, Schwenker, Lena Sophie et al.2023 · 19 citationsThe Journal of biological chemistry. 2023;299(9):105088
Can physiologic colonic [18F]FDG uptake in PET/CT imaging predict response to immunotherapy in metastatic melanoma?37452874 · Sachpekidis, Christos, Stein-Thoeringer, Christoph K, Kopp-Schneider, Annette et al.2026 · 14 citationsEuropean journal of nuclear medicine and molecular imaging. 2023;50(12):3709-3722
Optimizing expert and patient input in pediatric trial design: Lessons learned and recommendations from a collaboration between conect4children and European Patient-CEntric ClinicAl TRial PLatforms.37391924 · Dhaenens, Britt A E, Mahler, Fenna, Batchelor, Hannah et al.2023 · 10 citationsClinical and translational science. 2023;16(8):1458-1468
Correction : Pulmonary magnetic resonance-guided online adaptive radiotherapy of locally advanced non-small cell lung cancer: the PUMA trial.37291628 · Regnery, Sebastian, de Colle, Chiara, Eze, Chukwuka et al.2023 · 1 citationRadiation oncology (London, England). 2023;18(1):99
Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.37364231 · Heipertz, Anna-Elisa, Pajtler, Kristian W, Pfaff, Elke et al.2023 · 32 citationsJCO precision oncology. 2023;7:e2300015
Pulmonary magnetic resonance-guided online adaptive radiotherapy of locally advanced: the PUMA trial.37143154 · Regnery, Sebastian, de Colle, Chiara, Eze, Chukwuka et al.2023 · 18 citationsRadiation oncology (London, England). 2023;18(1):74
The prognostic value of [18F]FDG PET/CT based response monitoring in metastatic melanoma patients undergoing immunotherapy: comparison of different metabolic criteria.37099131 · Sachpekidis, Christos, Weru, Vivienn, Kopp-Schneider, Annette et al.2023 · 20 citationsEuropean journal of nuclear medicine and molecular imaging. 2023;50(9):2699-2714
Why is the winner the best?2303.17719v1 · Matthias Eisenmann, Annika Reinke, Vivienn Weru et al.2023 · 8 citationsarXiv
Spectral imaging enables contrast agent-free real-time ischemia monitoring in laparoscopic surgery.36897951 · Ayala, Leonardo, Adler, Tim J, Seidlitz, Silvia et al.2023 · 40 citationsScience advances. 2023;9(10):eadd6778
Beyond rankings: Learning (more) from algorithm validation.36965252 · Roß, Tobias, Bruno, Pierangela, Reinke, Annika et al.2023 · 18 citationsMedical image analysis. 2023;86:102765
Simulating and reporting frequentist operating characteristics of clinical trials that borrow external information2302.12651v1 · Annette Kopp-Schneider, Manuel Wiesenfarth, Leonhard Held et al.2023 · 0 citationsarXiv
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