CL

Christopher T. Lee

0000-0002-0670-2308

biophysicsmitochondriaq-bio.QMcardiolipinCardiolipinscell biologyMitochondrianeuroscienceq-bio.MNCell Membrane

On Valency

published · living versions

Anatomy-specific classification of medical images using deep convolutional nets

with Holger R. Roth, Hoo-Chang Shin, Ari Seff, Lauren Kim +3

1 version

W_r7td4em6v1 · current

Preprints & journals

58 papers in the corpus · 2004–2026

Physics-Guided Neural Reconstruction of Cellular Membranes for 3D Electron Microscopy.

Matsuda, Atsushi, Kim, Se Min, Akamatsu, Matthew et al.

0 citations

426201602026bioRxiv : the preprint server for biology. 2026

Size-dependent nucleus-vacuole interactions in budding yeast demonstrate a role for steric packing in organelle shape and positioning.

Mirvis, Mary, Akenuwa, Oghosa H, Tan, Irene et al.

0 citations

421822422026bioRxiv : the preprint server for biology. 2026

Membrane Phase, Charge, and Curvature Regulate α-Synuclein Binding Dynamics.

Kou, Orianna H, Sakurai, Cailyn M, Ramirez, Stephanie Y et al.

1 citation

421823072026bioRxiv : the preprint server for biology. 2026

Saturated cardiolipins are potent disruptors of inner mitochondrial membrane structure and function.

Venkatraman, Kailash, Milshteyn, Daniel, Sarto, Carolina et al.

1 citation

420395242026bioRxiv : the preprint server for biology. 2026

Local enrichment of cardiolipin to transient membrane undulations.

Lee, Christopher T, Venkatraman, Kailash, Budin, Itay et al.

5 citations

405743312025Biophysical journal. 2025;124(15):2476-2487

Coupling between membrane undulations and lipid curvature leads to transient local enrichment of cardiolipin in mitochondrial membranes.

Lee, Christopher T, Venkatraman, Kailash, Budin, Itay et al.

5 citations

398965422025bioRxiv : the preprint server for biology. 2025

Mechanochemical feedback between confinement and actin crosslinking drives the shape dynamics of liquid-like droplets.

Mansour, Daniel, Jordan, Dominique, Walker, Caleb et al.

2 citations

406615722026bioRxiv : the preprint server for biology. 2025

Spatial transcriptomics of the aging mouse brain reveals origins of inflammation in the white matter.

Wang, Lin, Cui, Chang-Yi, Lee, Christopher T et al.

32 citations

401857502025Nature communications. 2025;16(1):3231

Author Correction: Spatial modeling algorithms for reactions and transport in biological cells.

Francis, Emmet A, Laughlin, Justin G, Dokken, Jørgen S et al.

0 citations

399010552026Nature computational science. 2025;5(2):185

Spatial modeling algorithms for reactions and transport in biological cells.

Francis, Emmet A, Laughlin, Justin G, Dokken, Jørgen S et al.

12 citations

397028392025Nature computational science. 2025;5(1):76-89

Membrane mechanics dictate axonal pearls-on-a-string morphology and function.

Griswold, Jacqueline M, Bonilla-Quintana, Mayte, Pepper, Renee et al.

33 citations

396232182025Nature neuroscience. 2025;28(1):49-61

Size-Dependent Nascent Sea Spray Aerosol Bounce Fractions and Estimated Viscosity: The Role of Divalent Cation Enrichment, Surface Tension, and the Kelvin Effect.

Tumminello, Paul R, Niles, Renee, Valdez, Vanessa et al.

14 citations

394408822024Environmental science & technology. 2024;58(44):19666-19678

Setting the curve: the biophysical properties of lipids in mitochondrial form and function.

Venkatraman, Kailash, Lee, Christopher T, Budin, Itay

33 citations

393039822024Journal of lipid research. 2024;65(10):100643

Effects of Relative Humidity and Phase on the Molecular Detection of Nascent Sea Spray Aerosol Using Extractive Electrospray Ionization.

Kruse, Samantha M, Tumminello, Paul R, Moore, Alexia N et al.

9 citations

390470642024Analytical chemistry. 2024;96(31):12901-12907

Effects of Wind Speed on Size-Dependent Morphology and Composition of Sea Spray Aerosols.

Madawala, Chamika K, Molina, Carolina, Kim, Deborah et al.

17 citations

391662612024ACS earth & space chemistry. 2024;8(8):1609-1622

Biophysical Modeling of Synaptic Plasticity.

Lee, Christopher T, Bell, Miriam, Bonilla-Quintana, Mayte et al.

12 citations

383821152024Annual review of biophysics. 2024;53(1):397-426

Spatial modeling algorithms for reactions and transport (SMART) in biological cells

Emmet A. Francis, Justin G. Laughlin, J\orgen S. Dokken et al.

1 citation

2405.15968v12024arXiv

Modeling the mechanochemical feedback for membrane-protein interactions using a continuum mesh model.

Lee, Christopher T, Rangamani, Padmini

1 citation

390255772024Methods in enzymology. 2024;701:387-424

Cristae formation is a mechanical buckling event controlled by the inner mitochondrial membrane lipidome.

Venkatraman, Kailash, Lee, Christopher T, Garcia, Guadalupe C et al.

64 citations

379336002023The EMBO journal. 2023;42(24):e114054

ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization.

Nakamura, Hideki, Rho, Elmer, Lee, Christopher T et al.

28 citations

377343822023Cell reports. 2023;42(10):113089

Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome.

Venkatraman, Kailash, Lee, Christopher T, Garcia, Guadalupe C et al.

6 citations

369933702025bioRxiv : the preprint server for biology. 2023

Membrane mechanics dictate axonal morphology and function.

Griswold, Jacqueline M, Bonilla-Quintana, Mayte, Pepper, Renee et al.

6 citations

375031052024bioRxiv : the preprint server for biology. 2023

The ins and outs of membrane bending by intrinsically disordered proteins.

Yuan, Feng, Lee, Christopher T, Sangani, Arjun et al.

41 citations

374185232023Science advances. 2023;9(27):eadg3485

SMART: Spatial Modeling Algorithms for Reaction and Transport

Justin G. Laughlin, J\orgen S. Dokken, Henrik N.T. Finsberg et al.

1 citation

2306.07368v12023arXiv

Defining collaborative surveillance to improve decision making for public health emergencies and beyond.

Archer, Brett N, Abdelmalik, Philip, Cognat, Sebastien et al.

30 citations

372301042023Lancet (London, England). 2023;401(10391):1831-1834

The road to achieving epidemic-ready primary health care.

Frieden, Thomas R, Lee, Christopher T, Lamorde, Mohammed et al.

46 citations

371202622023The Lancet. Public health. 2023;8(5):e383-e390

Spatiotemporal modelling reveals geometric dependence of AMPAR dynamics on dendritic spine morphology.

Bell, Miriam K, Lee, Christopher T, Rangamani, Padmini

7 citations

363260202023The Journal of physiology. 2023;601(15):3329-3350

Role of the Triplet State and Protein Dynamics in the Formation and Stability of the Tryptophan Radical in an Apoazurin Mutant.

López-Peña, Ignacio, Lee, Christopher T, Rivera, Joel J et al.

9 citations

359770672022The journal of physical chemistry. B. 2022;126(36):6751-6761

Dendritic spine morphology regulates calcium-dependent synaptic weight change.

Bell, Miriam K, Holst, Maven V, Lee, Christopher T et al.

24 citations

358193652022The Journal of general physiology. 2022;154(8)

Mem3DG: Modeling membrane mechanochemical dynamics in 3D using discrete differential geometry.

Zhu, Cuncheng, Lee, Christopher T, Rangamani, Padmini

21 citations

361572692023Biophysical reports. 2022;2(3)

Development of a simple and effective online training for health workers: results from a pilot in Nigeria.

Thomas, Marshall P, Kozikott, Samantha, Kamateeka, Moreen et al.

28 citations

353138342022BMC public health. 2022;22(1):551

Benchmarking ensemble docking methods in D3R Grand Challenge 4.

Gan, Jessie Low, Kumar, Dhruv, Chen, Cynthia et al.

9 citations

351992212022Journal of computer-aided molecular design. 2022;36(2):87-99

Mem3DG: Modeling Membrane Mechanochemical Dynamics in 3D using Discrete Differential Geometry

Cuncheng Zhu, Christopher T. Lee, Padmini Rangamani

5 citations

2111.04460v12021arXiv

Morphological principles of neuronal mitochondria.

Mendelsohn, Rachel, Garcia, Guadalupe C, Bartol, Thomas M et al.

39 citations

346089952022The Journal of comparative neurology. 2022;530(6):886-902

SamQL: a structured query language and filtering tool for the SAM/BAM file format.

Lee, Christopher T, Maragkakis, Manolis

4 citations

346004802021BMC bioinformatics. 2021;22(1):474

Independent Markov decomposition: Toward modeling kinetics of biomolecular complexes.

Hempel, Tim, Del Razo, Mauricio J, Lee, Christopher T et al.

23 citations

343213562021Proceedings of the National Academy of Sciences of the United States of America. 2021;118(31)

7-1-7: an organising principle, target, and accountability metric to make the world safer from pandemics.

Frieden, Thomas R, Lee, Christopher T, Bochner, Aaron F et al.

90 citations

342425632021Lancet (London, England). 2021;398(10300):638-640

Value of models for membrane budding.

Lee, Christopher T, Akamatsu, Matthew, Rangamani, Padmini

16 citations

337062322021Current opinion in cell biology. 2021;71:38-45

Benchmarking ensemble docking methods as a scientific outreach project

Gan, J. L., Kumar, D., Chen, C. et al.

1 citation

10.1101/2020.10.02.324343v12020bioRxiv

3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries.

Lee, Christopher T, Laughlin, Justin G, Angliviel de La Beaumelle, Nils et al.

64 citations

322514482020PLoS computational biology. 2020;16(4):e1007756

An Open-Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries.

Lee, Christopher T, Laughlin, Justin G, Moody, John B et al.

34 citations

320325032021Biophysical journal. 2020;118(5):1003-1008

Applications and Challenges of Machine Learning to Enable Realistic Cellular Simulations.

Vasan, Ritvik, Rowan, Meagan P, Lee, Christopher T et al.

11 citations

361884162026Frontiers in physics. 2020;7

Trajectories of functional impairment in homeless older adults: Results from the HOPE HOME study.

Brown, Rebecca T, Guzman, David, Kaplan, Lauren M et al.

25 citations

314084882020PloS one. 2019;14(8):e0221020

Structural basis for ligand modulation of the CCR2 conformational landscape.

Taylor, Bryn C, Lee, Christopher T, Amaro, Rommie E

42 citations

309757552020Proceedings of the National Academy of Sciences of the United States of America. 2019;116(17):8131-8136

Exascale Computing: A New Dawn for Computational Biology.

Lee, Christopher T, Amaro, Rommie E

31 citations

309838892020Computing in science & engineering. 2018;20(5):18-25

Quantitative Ranking of Ligand Binding Kinetics with a Multiscale Milestoning Simulation Approach.

Jagger, Benjamin R, Lee, Christopher T, Amaro, Rommie E

41 citations

300708442018The journal of physical chemistry letters. 2018;9(17):4941-4948

The Implementation of the Colored Abstract Simplicial Complex and its Application to Mesh Generation

C.T. Lee, J.B. Moody, R.E. Amaro et al.

8 citations

1807.01417v22018ACM Trans. Math. Softw. 45, 3, Article 28 (August 2019)

A Systems Approach to Healthcare Innovation Using the MIT Hacking Medicine Model.

Gubin, Tatyana A, Iyer, Hari P, Liew, Shirlene N et al.

23 citations

287501992019Cell systems. 2017;5(1):6-10

Two Relations to Estimate Membrane Permeability Using Milestoning.

Votapka, Lane W, Lee, Christopher T, Amaro, Rommie E

45 citations

271546392018The journal of physical chemistry. B. 2016;120(33):8606-16

Simulation-Based Approaches for Determining Membrane Permeability of Small Compounds.

Lee, Christopher T, Comer, Jeffrey, Herndon, Conner et al.

233 citations

270434292017Journal of chemical information and modeling. 2016;56(4):721-33

Career total: 94 works. 58 are in this corpus.Showing the 50 most recent.

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94

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