JC
Jean Clairambault
Models, Biologicalmath.APNeoplasmsHeart RateMathematical oncologymath.SPPhenotypeq-bio.CBq-bio.TOBiological Evolution
On Valency
published · living versionsW_26jt8euu·v1 · currentpublished
An inequality for the Perron and Floquet eigenvalues of monotone differential systems and age structured equations
with Stephane Gaubert, Benoit Perthame
1 version
Preprints & journals
53 papers in the corpus · 1992–2024Stepping From Modeling Cancer Plasticity to the Philosophy of Cancer.33329717 · Clairambault, Jean2024 · 5 citationsFrontiers in genetics. 2020;11:579738
Phenotype divergence and cooperation in isogenic multicellularity and in cancer.38970827 · Ernesto Alvarez, Frank, Clairambault, Jean2024 · 3 citationsMathematical medicine and biology : a journal of the IMA. 2024;41(2):135-155
Phenotype divergence and cooperation in isogenic multicellularity and in cancer2306.16880v2 · Frank Alvarez (CEREMADE, INSA Toulouse), Jean Clairambault (MAMBA et al.2023 · 0 citationsarXiv
A phenotype-structured model for the tumour-immune response2301.05473v3 · Zineb Kaid, Camille Pouchol (MAP5 - UMR 8145), Jean Clairambault (LJLL (UMR\_7598) et al.2023 · 5 citationsarXiv
Evolution of a structured cell population endowed with plasticity of traits under constraints on and between the traits.36331628 · Alvarez, Frank Ernesto, Carrillo, José Antonio, Clairambault, Jean2022 · 9 citationsJournal of mathematical biology. 2022;85(6-7):64
Perspectives in cancer treatment: Reply to comments on "Improving cancer treatments via dynamical biophysical models".35636229 · Kuznetsov, M, Clairambault, J, Volpert, V2022 · 1 citationPhysics of life reviews. 2022;42:15-18
Improving cancer treatments via dynamical biophysical models.34688561 · Kuznetsov, M, Clairambault, J, Volpert, V2022 · 66 citationsPhysics of life reviews. 2021;39:1-48
Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma.31907355 · Rabé, Marion, Dumont, Solenne, Álvarez-Arenas, Arturo et al.2021 · 97 citationsCell death & disease. 2020;11(1):19
Cell plasticity in cancer cell populations.32595946 · Shen, Shensi, Clairambault, Jean2020 · 89 citationsF1000Research. 2020;9
Adaptive dynamics of hematopoietic stem cells and their supporting stroma: a model and mathematical analysis.31499692 · Nguyen, Thanh Nam, Clairambault, Jean, Jaffredo, Thierry et al.2020 · 10 citationsMathematical biosciences and engineering : MBE. 2019;16(5):4818-4845
Optimizing cancer pharmacotherapeutics using mathematical modeling and a systems biology approach.29783516 · Clairambault, Jean2019 · 13 citationsPersonalized medicine. 2011;8(3):271-286
Control in dormancy or eradication of cancer stem cells: Mathematical modeling and stability issues.29678688 · Djema, Walid, Bonnet, Catherine, Mazenc, Frédéric et al.2019 · 16 citationsJournal of theoretical biology. 2018;449:103-123
Genotype- or Phenotype-Targeting Anticancer Therapies? Lessons from Tumor Evolutionary Biology.27587198 · Escargueil, Alexandre E, Prado, Soizic, Dezaire, Ambre et al.2018 · 10 citationsCurrent pharmaceutical design. 2016;22(44):6625-6644
Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations.27550042 · Lorenzi, Tommaso, Chisholm, Rebecca H, Clairambault, Jean2017 · 88 citationsBiology direct. 2016;11:43
Cell population heterogeneity and evolution towards drug resistance in cancer: Biological and mathematical assessment, theoretical treatment optimisation.27339473 · Chisholm, Rebecca H, Lorenzi, Tommaso, Clairambault, Jean2017 · 102 citationsBiochimica et biophysica acta. 2016;1860(11 Pt B):2627-45
Asymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapy1612.04698v1 · Camille Pouchol (UPMC, LJLL, MAMBA) et al.2016 · 80 citationsarXiv
Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors.25480478 · Lorz, Alexander, Lorenzi, Tommaso, Clairambault, Jean et al.2016 · 127 citationsBulletin of mathematical biology. 2015;77(1):1-22
Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation.25627977 · Chisholm, Rebecca H, Lorenzi, Tommaso, Lorz, Alexander et al.2015 · 151 citationsCancer research. 2015;75(6):930-9
The dynamics of p53 in single cells: physiologically based ODE and reaction-diffusion PDE models.25075792 · Eliaš, Ján, Dimitrio, Luna, Clairambault, Jean et al.2015 · 44 citationsPhysical biology. 2014;11(4):045001
Physiologically based mathematical models to optimize therapies against metastatic colorectal cancer: a mini-review.23530495 · Ballesta, Annabelle, Clairambault, Jean2014 · 18 citationsCurrent pharmaceutical design. 2014;20(1):37-48
Reaction-diffusion systems for spatio-temporal intracellular protein networks: A beginner's guide with two examples.25210594 · Eliaš, Ján, Clairambault, Jean2014 · 21 citationsComputational and structural biotechnology journal. 2014;10(16):12-22
Enabling multiscale modeling in systems medicine.25031615 · Wolkenhauer, Olaf, Auffray, Charles, Brass, Olivier et al.2014 · 85 citationsGenome medicine. 2014;6(3):21
The p53 protein and its molecular network: modelling a missing link between DNA damage and cell fate.24113167 · Eliaš, Ján, Dimitrio, Luna, Clairambault, Jean et al.2014 · 70 citationsBiochimica et biophysica acta. 2014;1844(1 Pt B):232-47
Effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors1312.6237v1 · Alexander Lorz, Tommaso Lorenzi, Jean Clairambault et al.2013 · 28 citationsarXiv
Can theorems help treat cancer?22350095 · Clairambault, Jean2013 · 7 citationsJournal of mathematical biology. 2013;66(7):1555-8
Age-structured cell population model to study the influence of growth factors on cell cycle dynamics.23311359 · Billy, Frédérique, Clairambault, Jean, Delaunay, Franck et al.2013 · 37 citationsMathematical biosciences and engineering : MBE. 2013;10(1):1-17
A spatial physiological model for p53 intracellular dynamics.22982291 · Dimitrio, Luna, Clairambault, Jean, Natalini, Roberto2013 · 29 citationsJournal of theoretical biology. 2013;316:9-24
Applying ecological and evolutionary theory to cancer: a long and winding road.23397042 · Thomas, Frédéric, Fisher, Daniel, Fort, Philippe et al.2013 · 81 citationsEvolutionary applications. 2013;6(1):1-10
Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies1207.0923v1 · Alexander Lorz, Tommaso Lorenzi, Michael E. Hochberg (ISEM) et al.2012 · 15 citationsarXiv
Commitment of mathematicians in medicine: a personal experience, and generalisations.22033649 · Clairambault, Jean2012 · 3 citationsActa biotheoretica. 2011;59(3-4):201-11
A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery.21931543 · Ballesta, Annabelle, Dulong, Sandrine, Abbara, Chadi et al.2012 · 71 citationsPLoS computational biology. 2011;7(9):e1002143
Comparison of Perron and Floquet eigenvalues in age structured cell division cycle models0812.0803v1 · Jean Clairambault, St'ephane Gaubert, Thomas Lepoutre2008 · 32 citationsMath. Model. Nat. Phenom., Volume 4, Number 3, 2009, pp.183 - 209
Circadian rhythm and cell population growth1006.3459v1 · Jean Clairambault, Stephane Gaubert, Thomas Lepoutre2010 · 29 citationsMathematical and Computer Modelling, Volume 53, Issues 7-8, April 2011, Pages 1558-1567
Modelling the spatial organization of cell proliferation in the developing central nervous system1005.0207v1 · Jean Clairambault, Vladimir Flores (CONICET), Benoit Perthame et al.2010 · 0 citationsarXiv
Modelling the genesis and treatment of cancer: the potential role of physiologically based pharmacodynamics.19954965 · Steimer, Jean-Louis, Dahl, Svein G, De Alwis, Dinesh P et al.2010 · 10 citationsEuropean journal of cancer (Oxford, England : 1990). 2010;46(1):21-32
Circadian timing in cancer treatments.20055686 · Lévi, Francis, Okyar, Alper, Dulong, Sandrine et al.2010 · 491 citationsAnnual review of pharmacology and toxicology. 2010;50:377-421
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics.18644767 · Lévi, Francis, Altinok, Atilla, Clairambault, Jean et al.2008 · 77 citationsPhilosophical transactions. Series A, Mathematical, physical, and engineering sciences. 2008;366(1880):3575-98
An age-and-cyclin-structured cell population model for healthy and tumoral tissues.18064465 · Bekkal Brikci, Fadia, Clairambault, Jean, Ribba, Benjamin et al.2008 · 82 citationsJournal of mathematical biology. 2008;57(1):91-110
A step toward optimization of cancer therapeutics. Physiologically based modeling of circadian control on cell proliferation.18270046 · Clairambault, Jean2008 · 15 citationsIEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 2008;27(1):20-4
Rhythms from seconds to days: part 2. Cell proliferation.18306502 · Clairambault, Jean, Hoyer, Dirk2008 · 0 citationsIEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 2008;27(1):16
Physiologically based modelling of circadian control on cell proliferation.17946797 · Clairambault, Jean2008 · 12 citationsConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2006;2006:173-6
Rhythms from seconds to days. Physiological importance and therapeutic implications.18189080 · Hoyer, Dirk, Clairambault, Jean2008 · 7 citationsIEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 2007;26(6):12-3
Modeling oxaliplatin drug delivery to circadian rhythms in drug metabolism and host tolerance.17707544 · Clairambault, Jean2008 · 34 citationsAdvanced drug delivery reviews. 2007;59(9-10):1054-68
An inequality for the Perron and Floquet eigenvalues of monotone differential systems and age structured equations0704.3820v1 · Jean Clairambault, Stephane Gaubert, Benoit Perthame2007 · 26 citationsComptes Rendus Mathematique, Volume 345, Issue 10, 15 November 2007, Pages 549-554on Valency
[Toxicity and anti-tumour efficacy of oxaliplatin on Glasgow osteosarcoma induced in mice: a mathematical model].12852993 · Clairambault, Jean, Claude, Daniel, Filipski, Elisabeth et al.2003 · 6 citationsPathologie-biologie. 2003;51(4):212-5
Period shift induction by intermittent stimulation in a Drosophila model of PER protein oscillations.10672429 · Claude, D, Clairambault, J2000 · 13 citationsChronobiology international. 2000;17(1):1-14
Myocardial determinants in regulation of the heart rate.9428618 · Swynghedauw, B, Jasson, S, Clairambault, J et al.1998 · 6 citationsJournal of molecular medicine (Berlin, Germany). 1997;75(11-12):860-6
Heart rate and heart rate variability, a pharmacological target.9110110 · Swynghedauw, B, Jasson, S, Chevalier, B et al.1997 · 16 citationsCardiovascular drugs and therapy. 1997;10(6):677-85
Decreased heart rate variability in transgenic mice overexpressing atrial beta 1-adrenoceptors.8897941 · Mansier, P, Médigue, C, Charlotte, N et al.1996 · 75 citationsThe American journal of physiology. 1996;271(4 Pt 2):H1465-72
Linear and non-linear analyses of heart rate variability: a minireview.8681324 · Mansier, P, Clairambault, J, Charlotte, N et al.1996 · 125 citationsCardiovascular research. 1996;31(3):371-9
Career total: 221 works. 53 are in this corpus.Showing the 50 most recent.
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