JB
Josephine Barnes
Alzheimer's diseaseAlzheimer DiseaseMagnetic Resonance ImagingAgingAlzheimer’s diseaseCognitionCognitive DysfunctionWhite MatterSubtraction TechniqueBrain
On Valency
published · living versionsW_7d8qcew8·v1 · currentpublished
Evaluation of Uncertainty-Aware Multi-Software Ensembles for Hippocampal Segmentation
with Gabriel Oliveira-Stahl, Anna Schroder, James Moggridge, Hamza A. Salhab +4
1 version
Preprints & journals
121 papers in the corpus · 2003–2026Evaluation of Uncertainty-Aware Multi-Software Ensembles for Hippocampal Segmentation2610.31505v1 · Gabriel Oliveira-Stahl, Anna Schroder, James Moggridge et al.2026 · 0 citationsMachine.Learning.for.Biomedical.Imaging. 2026 (2026)on Valency
Location matters: Attributing cognitive symptoms to white matter hyperintensities in 3,481 memory clinic patients.42895925 · van der Lelij, Ewoud J, Coenen, Mirthe, de Kort, Floor A S et al.2026 · 0 citationsDementia and geriatric cognitive disorders. 2026:1
Examining the role of systemic inflammation as a mediator of the glycaemia-brain volume associations in women.41805754 · Fatih, Nasri, Chaturvedi, Nish, Garfield, Victoria et al.2026 · 1 citationPloS one. 2026;21(3):e0329046
Location patterns and longitudinal progression of white matter hyperintensities.41810374 · Zhao, Xin, Malone, Ian B, Brown, Thomas M et al.2026 · 0 citationsmedRxiv : the preprint server for health sciences. 2026
Retention and longitudinal change in Insight 46, an intensive neuroscience sub-study of the 1946 British birth cohort.41572318 · Keuss, Sarah E, Lu, Kirsty, James, Sarah-Naomi et al.2026 · 0 citationsBMC research notes. 2026;19(1):41
Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging.40829101 · Brown, Thomas M, James, Sarah-Naomi, Nicholas, Jennifer M et al.2025 · 5 citationsNeurology. 2025;105(5):e213975
Associations between night/shift working and late-life brain health.40677699 · King-Robson, Josh, Nicholas, Jennifer M, James, Sarah-Naomi et al.2025 · 3 citationsBrain communications. 2025;7(4):fcaf264
Sex differences between mid-life glycaemic traits and brain volume at age 70: a population-based study.40300998 · Fatih, Nasri, Hughes, Alun, Sudre, Carole H et al.2025 · 1 citationEuropean journal of endocrinology. 2025;192(5):K44-K49
Modifiable Vascular Risk Factors and Subsequent Brain Metrics in Hispanic/Latino Populations.40127390 · Barnes, Josephine, Prosser, Lloyd2025 · 0 citationsNeurology. 2025;104(8):e213547
Remote cognitive tests predict neurodegenerative biomarkers in the Insight 46 cohort.39936232 · Giovane, Martina Del, Giunchiglia, Valentina, Cai, Ziyuan et al.2025 · 9 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(2):e14572
The relationship between leisure time physical activity patterns, Alzheimer's disease markers and cognition.39898325 · James, Sarah-Naomi, Sudre, Carole H, Barnes, Josephine et al.2025 · 4 citationsBrain communications. 2025;7(1):fcae431
Biomarker pathway heterogeneity of amyloid-positive individuals.39417393 · Prosser, Lloyd, Sudre, Carole H, Oxtoby, Neil P et al.2024 · 7 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2024;20(12):8503-8515
Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.39173100 · Subramaniapillai, Sivaniya, Schindler, Louise S, Redmond, Paul et al.2024 · 12 citationsNeurology. 2024;103(6):e209744
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70.38199813 · Keuss, Sarah E, Coath, William, Cash, David M et al.2024 · 7 citationsJournal of neurology, neurosurgery, and psychiatry. 2024;95(8):748-752
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients.38477469 · Biesbroek, J Matthijs, Coenen, Mirthe, DeCarli, Charles et al.2024 · 37 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2024;20(4):2980-2989
Updating the study protocol: Insight 46 - a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development - phases 2 and 3.38263061 · Murray-Smith, Heidi, Barker, Suzie, Barkhof, Frederik et al.2024 · 12 citationsBMC neurology. 2024;24(1):40
Assessment of Microvascular Disease in Heart and Brain by MRI: Application in Heart Failure with Preserved Ejection Fraction and Cerebral Small Vessel Disease.37763715 · Bennett, Jonathan, van Dinther, Maud, Voorter, Paulien et al.2023 · 8 citationsMedicina (Kaunas, Lithuania). 2023;59(9)
Neuroimaging, clinical and life course correlates of normal-appearing white matter integrity in 70-year-olds.37680671 · James, Sarah-Naomi, Manning, Emily N, Storey, Mathew et al.2025 · 12 citationsBrain communications. 2023;5(5):fcad225
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts.38035457 · Coenen, Mirthe, Biessels, Geert Jan, DeCarli, Charles et al.2023 · 17 citationsNeuroImage. Clinical. 2023;40:103547
First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study.36522155 · O'Connor, Antoinette, Rice, Helen, Barnes, Josephine et al.2023 · 1 citationJournal of neurology, neurosurgery, and psychiatry. 2023;94(5):403-405
Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients.36504357 · Coenen, Mirthe, Kuijf, Hugo J, Huenges Wajer, Irene M C et al.2023 · 67 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2023;19(6):2420-2432
Polygenic coronary artery disease association with brain atrophy in the cognitively impaired.36523268 · de Silva, Eric, Sudre, Carole H, Barnes, Josephine et al.2025 · 9 citationsBrain communications. 2022;4(6):fcac314
Predicting Cognitive Decline in Older Adults Using Baseline Metrics of AD Pathologies, Cerebrovascular Disease, and Neurodegeneration.36357185 · Prosser, Lloyd, Macdougall, Amy, Sudre, Carole H et al.2023 · 25 citationsNeurology. 2023;100(8):e834-e845
Adulthood cognitive trajectories over 26 years and brain health at 70 years of age: findings from the 1946 British Birth Cohort.36470133 · James, Sarah-Naomi, Nicholas, Jennifer M, Lu, Kirsty et al.2023 · 6 citationsNeurobiology of aging. 2023;122:22-32
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.36102775 · Wagen, Aaron Z, Coath, William, Keshavan, Ashvini et al.2022 · 49 citationsThe lancet. Healthy longevity. 2022;3(9):e607-e616
Accelerated vascular aging: Ethnic differences in basilar artery length and diameter, and its association with cardiovascular risk factors and cerebral small vessel disease.35966566 · Sudre, Carole H, Moriconi, Stefano, Rehwald, Rafael et al.2026 · 6 citationsFrontiers in cardiovascular medicine. 2022;9:939680
Associations of β-Amyloid and Vascular Burden With Rates of Neurodegeneration in Cognitively Normal Members of the 1946 British Birth Cohort.35410910 · Keuss, Sarah E, Coath, William, Nicholas, Jennifer M et al.2022 · 38 citationsNeurology. 2022;99(2):e129-e141
Familial British dementia: a clinical and multi-modal imaging case study.35229189 · Harris, Matthew J, Lane, Christopher A, Coath, William et al.2022 · 7 citationsJournal of neurology. 2022;269(7):3926-3930
Circulating Metabolome and White Matter Hyperintensities in Women and Men.35050683 · Sliz, Eeva, Shin, Jean, Ahmad, Shahzad et al.2022 · 40 citationsCirculation. 2022;145(14):1040-1052
Straight and Divergent Pathways to Cognitive State: Seven Decades of Follow-Up in the British 1946 Birth Cohort.35964185 · Richards, Marcus, James, Sarah N, Lu, Kirsty et al.2022 · 1 citationJournal of Alzheimer's disease : JAD. 2022;89(2):659-667
Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial.34687634 · Kehoe, Patrick Gavin, Turner, Nicholas, Howden, Beth et al.2022 · 57 citationsThe Lancet. Neurology. 2021;20(11):895-906
Presumed small vessel disease, imaging and cognition markers in the Alzheimer's Disease Neuroimaging Initiative.34661106 · Fiford, Cassidy M, Sudre, Carole H, Young, Alexandra L et al.2025 · 9 citationsBrain communications. 2021;3(4):fcab226
Sex-related differences in whole brain volumes at age 70 in association with hyperglycemia during adult life.35183802 · Fatih, Nasrtullah, Chaturvedi, Nish, Lane, Christopher A et al.2022 · 9 citationsNeurobiology of aging. 2022;112:161-169
Investigating the relationship between BMI across adulthood and late life brain pathologies.33941254 · Lane, Christopher A, Barnes, Josephine, Nicholas, Jennifer M et al.2021 · 18 citationsAlzheimer's research & therapy. 2021;13(1):91
A population-based study of head injury, cognitive function and pathological markers.33694298 · James, Sarah-Naomi, Nicholas, Jennifer M, Lane, Christopher A et al.2022 · 9 citationsAnnals of clinical and translational neurology. 2021;8(4):842-856
The age-dependent associations of white matter hyperintensities and neurofilament light in early- and late-stage Alzheimer's disease.33070094 · Walsh, Phoebe, Sudre, Carole H, Fiford, Cassidy M et al.2021 · 28 citationsNeurobiology of aging. 2021;97:10-17
High blood pressure predicts hippocampal atrophy rate in cognitively impaired elders.32587882 · Fiford, Cassidy M, Nicholas, Jennifer M, Biessels, Geert Jan et al.2024 · 17 citationsAlzheimer's & dementia (Amsterdam, Netherlands). 2020;12(1):e12035
Non-memory cognitive symptom development in Alzheimer's disease.32078209 · Blenkinsop, A, van der Flier, W M, Wolk, D et al.2021 · 10 citationsEuropean journal of neurology. 2020;27(6):995-1002
CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease.32305782 · Walsh, Phoebe, Sudre, Carole H, Fiford, Cassidy M et al.2020 · 49 citationsNeurobiology of aging. 2020;91:5-14
Automated White Matter Hyperintensity Segmentation Using Bayesian Model Selection: Assessment and Correlations with Cognitive Change.32062817 · Fiford, Cassidy M, Sudre, Carole H, Pemberton, Hugh et al.2020 · 23 citationsNeuroinformatics. 2020;18(3):429-449
Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort.31682678 · Lane, Christopher A, Barnes, Josephine, Nicholas, Jennifer M et al.2020 · 105 citationsJAMA neurology. 2020;77(2):175-183
Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study.31444142 · Lane, Christopher A, Barnes, Josephine, Nicholas, Jennifer M et al.2020 · 247 citationsThe Lancet. Neurology. 2019;18(10):942-952
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.29914016 · Barnes, Josephine, Bartlett, Jonathan W, Wolk, David A et al.2019 · 36 citationsJournal of Alzheimer's disease : JAD. 2018;64(2):631-642
Patterns of progressive atrophy vary with age in Alzheimer's disease patients.29220823 · Fiford, Cassidy M, Ridgway, Gerard R, Cash, David M et al.2018 · 46 citationsNeurobiology of aging. 2018;63:22-32
A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.28316055 · Manning, Emily N, Leung, Kelvin K, Nicholas, Jennifer M et al.2018 · 18 citationsNeuroinformatics. 2017;15(2):215-226
APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis.28235680 · Sudre, Carole H, Cardoso, M Jorge, Frost, Chris et al.2017 · 65 citationsNeurobiology of aging. 2017;53:67-75
White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.27933676 · Fiford, Cassidy M, Manning, Emily N, Bartlett, Jonathan W et al.2018 · 95 citationsHippocampus. 2017;27(3):249-262
Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjects.26461053 · Manning, Emily N, Macdonald, Kate E, Leung, Kelvin K et al.2016 · 18 citationsHuman brain mapping. 2015;36(12):5123-36
Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia.26338813 · Bocchetta, Martina, Gordon, Elizabeth, Manning, Emily et al.2016 · 88 citationsJournal of neurology. 2015;262(12):2635-42
Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2.26194310 · Jack, Clifford R, Barnes, Josephine, Bernstein, Matt A et al.2016 · 220 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2015;11(7):740-56
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