AD
Alain Destexhe
Models, Neurologicalneuroscienceq-bio.NCNeural Networks, ComputerNeuronsBrainAction PotentialsComputer Simulationcerebral cortexcond-mat.dis-nn
On Valency
published · living versionsW_pgs5qvah·v1 · currentpublished
Calculating event-triggered average synaptic conductances from the membrane potential
with Martin Pospischil, Zuzanna Piwkowska, Michelle Rudolph, Thierry Bal
1 version
Preprints & journals
307 papers in the corpus · 1986–2026Modulation of intercolumnar synchronization by endogenous electric fields in cerebral cortex.33658192 · Rebollo, Beatriz, Telenczuk, Bartosz, Navarro-Guzman, Alvaro et al.2026 · 35 citationsScience advances. 2021;7(10)
Entropy and Complexity Tools Across Scales in Neuroscience: A Review.40003111 · Cofré, Rodrigo, Destexhe, Alain2026 · 16 citationsEntropy (Basel, Switzerland). 2025;27(2)
Multiscale modeling of neuronal dynamics in hippocampus CA1.39165754 · Tesler, Federico, Lorenzi, Roberta Maria, Ponzi, Adam et al.2026 · 14 citationsFrontiers in computational neuroscience. 2024;18:1432593
The transfer function as a method to reduce morphological models into point-neuron models.42722079 · Daou, Mikal, Jovanic, Tihana, Destexhe, Alain2026 · 0 citationsJournal of neuroscience methods. 2026;437:110899
A class of mean-field models to bridge molecular to brain scales2608.11185v1 · Alain Destexhe2026 · 0 citationsarXiv
Mechanistic bridges from receptors to whole-brain dynamics: mean-field reductions, validity domains, and computational trade-offs2608.00306v2 · Yannael Bossard, Lehna Bekri, Alain Destexhe2026 · 0 citationsarXiv
Simulated 5-HT2A receptor activation accounts for the high complexity of brain activity during psychedelic states10.1101/2025.10.20.683366v2 · Martin, H. M., Cofre, R., Destexhe, A.2025 · 0 citationsbioRxiv
A roadmap to navigate the future of neural engineering.42246470 · Grill, Warren M, Chestek, Cynthia, Wang, Yiwen et al.2026 · 0 citationsJournal of neural engineering. 2026;23(4)
State-dependent brain responsiveness, from local circuits to the whole brain2510.07956v2 · A. Destexhe, J Goldman, N. Tort-Colet et al.2025 · 2 citationsarXiv
A biologically plausible decision-making model based on interacting neural populations.41774750 · Baspinar, Emre, Cecchini, Gloria, DePass, Michael et al.2026 · 2 citationsPloS one. 2026;21(3):e0340393
Spatially structured heterogeneity shapes large-scale cortical dynamics in a model of the human cortex.42418484 · Dalla Porta, Leonardo, Fousek, Jan, Destexhe, Alain et al.2026 · 0 citationsProceedings of the National Academy of Sciences of the United States of America. 2026;123(28):e2532072123
Convergent transcriptomic and connectomic controllers of information integration and its anaesthetic breakdown across mammalian brains.41606107 · Luppi, Andrea I, Uhrig, Lynn, Tasserie, Jordy et al.2026 · 3 citationsNature human behaviour. 2026;10(4):777-802
Circadian Modulation of Excitation-Inhibition Balance Drives Ictal Transitions in a Mechanistic Model of Epileptic Networks10.64898/2026.05.22.726242v1 · Carannante, I., Dlima, N., Destexhe, A. et al.2026 · 0 citationsbioRxiv
EEG and Computational Aspects of How Ageing Affects Sleep Slow Waves.40992892 · El Kanbi, Karim, Tort-Colet, Núria, Benchenane, Karim et al.2026 · 4 citationsJournal of sleep research. 2026;35(3):e70214
A continuum of asynchronous states in cerebral cortex networks, and how they determine responsiveness10.64898/2026.05.06.723408v1 · Bassat, M., Tesler, F., Destexhe, A.2026 · 0 citationsbioRxiv
The transfer function as a tool to reduce morphological models into point-neuron models10.64898/2026.03.20.713213v1 · Daou, M., Jovanic, T., Destexhe, A.2026 · 0 citationsbioRxiv
Comprehensive profiling of anaesthetised brain dynamics across phylogeny10.1101/2025.03.22.644729v2 · Luppi, A. I., Uhrig, L., Tasserie, J. et al.2025 · 3 citationsbioRxiv
Convergent information flows explain recurring firing patterns in cerebral cortex.41361139 · Guarino, Domenico, Filipchuk, Anton, Destexhe, Alain2025 · 2 citationsNature neuroscience. 2025
A unified model library maps how neuromodulation reshapes the excitability landscape of neurons across the brain.41325433 · Guarino, Domenico, Carannante, Ilaria, Destexhe, Alain2025 · 1 citationPLoS computational biology. 2025;21(12):e1013765
Cortical modulation by exogenous electric fields is consistent with electric dipoles.41101621 · Covelo, Joana, Colom, Jaume, Weinert, Julia et al.2025 · 3 citationsNeuroscience. 2025;589:109-117
Listening to the sound of your own brain waves enhances sleep quality and quantity.40962569 · Aloulou, A, Chauvineau, M, Destexhe, A et al.2025 · 3 citationsSleep medicine. 2025;136:106755
Characterizing sleep stages through the complexity-entropy plane in human intracranial data and in a whole-brain model2511.09243v1 · Helena Bordini de Lucas, Leonardo Dalla Porta, Alain Destexhe et al.2025 · 0 citationsarXiv
Cholinergic heterogeneity facilitates synchronization and information flow in a whole-brain model10.1101/2025.10.28.685048v1 · Dalla Porta, L., Fousek, J., Destexhe, A. et al.2025 · 1 citationbioRxiv
Multiscale dynamical characterization of cortical brain states: from synchrony to asynchrony2510.05815v2 · Maria V. Sanchez-Vives, Arnau Manasanch, Andrea Pigorini et al.2025 · 3 citationsarXiv
Experimental and computational analysis of REM sleep distributed cortical activity in mice.40839408 · Peuvrier, Mathias, Fernandez, Laura, Crochet, Sylvain et al.2025 · 2 citationsJournal of neurophysiology. 2025;134(5):1378-1395
Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.41081761 · Hoffner, Guylaine, Castro, Pablo, Uhrig, Lynn et al.2025 · 2 citationseLife. 2025;13
A Chimera Model for Motion Anticipation in the Retina and the Primary Visual Cortex.40983061 · Emonet, Jérôme, Souihel, Selma, Chavane, Frédéric et al.2025 · 4 citationsNeural computation. 2025;37(11):1925-1974
Convergent information flows explain recurring firing patterns in cerebral cortex10.1101/2025.10.05.680498v1 · Guarino, D. G., Filipchuk, A., Destexhe, A.2025 · 2 citationsbioRxiv
The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing.40800542 · Amunts, Katrin, Axer, Markus, Banerjee, Swati et al.2025 · 48 citationsImaging neuroscience (Cambridge, Mass.). 2024;2
Biologically realistic mean field model of spiking neural networks with fast and slow inhibitory synapses.40266459 · Di Geronimo, Claudio, Destexhe, Alain, Di Volo, Matteo2025 · 0 citationsJournal of computational neuroscience. 2025;53(2):289-303
Variability of quantal synaptic currents in thalamocortical neurons.19936289 · Neubig, M, Destexhe, A, Sejnowski, T J2025 · 2 citationsThalamus & related systems. 2003;2(2):153-168
A computational approach to evaluate how molecular mechanisms impact large-scale brain activity.40437139 · Sacha, Maria, Tesler, Federico, Cofre, Rodrigo et al.2025 · 25 citationsNature computational science. 2025;5(5):405-417
Neuromodulators control neuronal dynamics through feature space reshaping10.1101/2025.05.19.654470v1 · Guarino, D., Carannante, I., Destexhe, A.2025 · 3 citationsbioRxiv
Dynamics and Bifurcation Structure of a Mean-Field Model of Adaptive Exponential Integrate-and-Fire Networks.40262748 · Kusch, Lionel, Depannemaecker, Damien, Destexhe, Alain et al.2025 · 5 citationsNeural computation. 2025;37(6):1102-1123
Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.10.1101/2024.03.27.586806v3 · Hoffner, G., Castro, P., Uhrig, L. et al.2024 · 2 citationsbioRxiv
Modeling impairment of ionic regulation with extended Adaptive Exponential integrate-and-fire models.39847247 · Depannemaecker, Damien, Tesler, Federico, Desroches, Mathieu et al.2025 · 5 citationsJournal of computational neuroscience. 2025;53(1):1-8
Listening to Your Own Brain Waves Sound Enhances Your Sleep Quality and Quantity10.1101/2025.03.31.646309v1 · Aloulou, A., Chauvineau, M., Destexhe, A. et al.2025 · 0 citationsbioRxiv
Biologically realistic mean field model of spiking neural networks with fast and slow inhibitory synapses10.1101/2025.02.28.640853v1 · Di Geronimo, C., Destexhe, A., Di Volo, M.2025 · 0 citationsbioRxiv
A biologically plausible decision-making model based on interacting neural populations10.1101/2023.02.28.530384v3 · Baspinar, E., Cecchini, G., DePass, M. et al.2023 · 2 citationsbioRxiv
A multi-scale study of thalamic state-dependent responsiveness.39671420 · Overwiening, Jorin, Tesler, Federico, Guarino, Domenico et al.2024 · 19 citationsPLoS computational biology. 2024;20(12):e1012262
A Whole-Brain Model of the Aging Brain During Slow Wave Sleep.39406483 · Lupi, Eleonora, Di Antonio, Gabriele, Angiolelli, Marianna et al.2024 · 3 citationseNeuro. 2024;11(11)
A Multi-Scale Study of Thalamic State-Dependent Responsiveness10.1101/2023.12.02.567941v3 · Overwiening, J., Tesler, F., Guarino, D. et al.2023 · 19 citationsbioRxiv
JCNS goes multiscale.39186186 · Destexhe, Alain, Victor, Jonathan2024 · 0 citationsJournal of computational neuroscience. 2024;52(4):245
Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans.39349600 · Castro, Pablo, Luppi, Andrea, Tagliazucchi, Enzo et al.2024 · 30 citationsCommunications biology. 2024;7(1):1224
Noise Enhancement of Neural Information Processing.36554242 · Destexhe, Alain2024 · 8 citationsEntropy (Basel, Switzerland). 2022;24(12)
Mean-field based framework for forward modeling of LFP and MEG signals.36313811 · Tesler, Federico, Tort-Colet, Núria, Depannemaecker, Damien et al.2024 · 29 citationsFrontiers in computational neuroscience. 2022;16:968278
Cognitive mechanisms of learning in sequential decision-making under uncertainty: an experimental and theoretical approach.39188591 · Cecchini, Gloria, DePass, Michael, Baspinar, Emre et al.2024 · 6 citationsFrontiers in behavioral neuroscience. 2024;18:1399394
Modeling impairment of ionic regulation with extended Adaptive Exponential integrate-and-fire models10.1101/2024.08.01.606188v1 · Depannemaecker, D., Tesler, F., Desroches, M. et al.2024 · 5 citationsbioRxiv
EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures.38976325 · Stenroos, Petteri, Guillemain, Isabelle, Tesler, Federico et al.2024 · 12 citationseLife. 2024;12
EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures10.1101/2023.07.26.550701v4 · Stenroos, P., Guillemain, I., Tesler, F. et al.2023 · 12 citationsbioRxiv
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