EH
Espen Hagen
Models, NeurologicalneuroscienceMoBapsychiatry and clinical psychologyq-bio.NCgenetic and genomic medicinelocal field potentialbipolar disorderCognitionGenome-Wide Association Study
On Valency
published · living versionsW_xzbxbhnu·v1 · currentpublished
Hybrid scheme for modeling local field potentials from point-neuron networks
with David Dahmen, Maria L. Stavrinou, Henrik Lindén, Tom Tetzlaff +4
1 version
Preprints & journals
61 papers in the corpus · 2008–2026Large-Scale Neuroimaging and Genetic Analyses of the Human Thalamus in Loneliness.42733593 · Mäki-Marttunen, Verónica, Sailer, Uta, Kopal, Jakub et al.2026 · 0 citationsBiological psychiatry global open science. 2026;6(6):100798
Family genetic designs in MoBa provide insights into health and functioning.42618792 · Corfield, Elizabeth C, Shadrin, Alexey A, Frei, Oleksandr et al.2026 · 3 citationsNature. 2026
Genetic liability to addiction underlies comorbid bipolar and substance use disorders.42636965 · Ystaas, Lars A R, Parekh, Pravesh, Parker, Nadine et al.2026 · 0 citationsBiological psychiatry. 2026
State-dependent brain responsiveness, from local circuits to the whole brain2510.07956v2 · A. Destexhe, J Goldman, N. Tort-Colet et al.2025 · 2 citationsarXiv
Prediction of adolescent internalizing disorder risk: Evidence from the Norwegian mother, father, and child cohort study.41734834 · Frei, Evgeniia, Frei, Oleksandr, Hagen, Espen et al.2026 · 0 citationsJournal of affective disorders. 2026;404:121481
Multimodal Prediction of Psychosis in the Prospective MoBa Birth Cohort.40585239 · Birkenæs, Viktoria, Parekh, Pravesh, Shadrin, Alexey et al.2026 · 0 citationsResearch square. 2025
Genetic liability to addiction underlies comorbid bipolar and substance use disorders10.64898/2026.02.04.26345483v1 · Ystaas, L. A. R., Parekh, P., Parker, N. et al.2026 · 0 citationsmedRxiv
Bivariate GSA-MiXeR: A Novel Tool for Functional Genomic Analyses Implicates Diverse Neural Cell Types for Psychiatric and Neurodegenerative Disorders10.64898/2025.12.16.25342384v1 · Parker, N., Furher, J., Nguyen, D. et al.2025 · 0 citationsmedRxiv
Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression.41233554 · Shorter, John R, Pasman, Joëlle A, Kurvits, Siim et al.2025 · 12 citationsNature genetics. 2025;57(12):2972-2979
Prediction of Adolescent Internalizing Disorder Risk: Evidence from the Norwegian Mother, Father, and Child Cohort Study10.1101/2025.11.12.25340071v1 · Frei, E., Frei, O., Hagen, E. et al.2025 · 0 citationsmedRxiv
The phenotypic and genetic relationship between adolescent mental health and time spent on social media, gaming, and TV.41061597 · Frei, Evgeniia, Frei, Oleksandr, Jaholkowski, Piotr et al.2025 · 5 citationsPsychiatry research. 2025;353:116761
Distinct patterns of genetic overlap among multimorbidities revealed with trivariate MiXeR.41023670 · Shadrin, Alexey A, Hindley, Guy, Hagen, Espen et al.2025 · 2 citationsGenome medicine. 2025;17(1):106
Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer's Disease in European Populations: Development and Validation10.1101/2025.07.28.25332293v1 · Akdeniz, B. C., Bahrami, S., Hagen, E. et al.2025 · 2 citationsmedRxiv
The phenotypic and genetic relationship between adolescent mental health and time spent on social media, gaming, and TV10.1101/2023.09.14.23295537v3 · Frei, E., Frei, O., Jaholkowski, P. P. et al.2023 · 5 citationsmedRxiv
Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders.39462222 · Bakken, Nora R, Parker, Nadine, Hannigan, Laurie J et al.2025 · 8 citationsJournal of child psychology and psychiatry, and allied disciplines. 2025;66(3):350-365
Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development.39608471 · Jaholkowski, Piotr, Bahrami, Shahram, Fominykh, Vera et al.2024 · 2 citationsNeurobiology of disease. 2024;203:106750
Reconciliation of weak pairwise spike-train correlations and highly coherent local field potentials across space1805.10235v3 · Johanna Senk, Espen Hagen, Sacha J. van Albada et al.2018 · 18 citationsCerebral Cortex 34(10): bhae405 (2024)
Unraveling the shared genetics of common epilepsies and general cognitive ability.39388989 · Karadag, Naz, Hagen, Espen, Shadrin, Alexey A et al.2024 · 6 citationsSeizure. 2024;122:105-112
Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders.31440172 · Mäki-Marttunen, Tuomo, Kaufmann, Tobias, Elvsåshagen, Torbjørn et al.2024 · 31 citationsFrontiers in psychiatry. 2019;10:534
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets.38831010 · Frei, Oleksandr, Hindley, Guy, Shadrin, Alexey A et al.2024 · 35 citationsNature genetics. 2024;56(6):1310-1318
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology.38817246 · Karadag, Naz, Hagen, Espen, Shadrin, Alexey A et al.2024 · 6 citationsNeurology. Genetics. 2024;10(3):e200143
COSGAP: COntainerized Statistical Genetics Analysis Pipelines.38808072 · Akdeniz, Bayram Cevdet, Frei, Oleksandr, Hagen, Espen et al.2024 · 10 citationsBioinformatics advances. 2024;4(1):vbae067
Unraveling the shared genetics of common epilepsies and general cognitive ability.10.1101/2024.03.25.24304773v1 · Karadag, N., Hagen, E., Shadrin, A. A. et al.2024 · 7 citationsmedRxiv
Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR10.1101/2024.02.23.24303236v1 · Shadrin, A. A., Hindley, G., Hagen, E. et al.2024 · 8 citationsmedRxiv
Sourcing Bivariate Genetic Overlap for Polygenic Prediction using MiXeR-Pred10.1101/2024.02.19.24303039v1 · Parker, N., Cheng, W., Hindley, G. F. L. et al.2024 · 5 citationsmedRxiv
Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders10.1101/2023.11.21.23298804v1 · Bakken, N. R., Parker, N., Hannigan, L. J. et al.2023 · 8 citationsmedRxiv
Uncovering circuit mechanisms of current sinks and sources with biophysical simulations of primary visual cortex.37486105 · Rimehaug, Atle E, Stasik, Alexander J, Hagen, Espen et al.2023 · 49 citationseLife. 2023;12
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.37252880 · Holen, Børge, Shadrin, Alexey A, Icick, Romain et al.2023 · 16 citationsAddiction biology. 2023;28(6):e13282
COGEDAP: A COmprehensive GEnomic Data Analysis Platform2212.14103v1 · Bayram Cevdet Akdeniz, Oleksandr Frei, Espen Hagen et al.2022 · 2 citationsarXiv
Conditions for wave trains in spiking neural networks1801.06046v2 · Johanna Senk, Karol'ina Korvasov'a, Jannis Schuecker et al.2018 · 28 citationsPhys. Rev. Research 2, 023174 (2020)
VIOLA - A multi-purpose and web-based visualization tool for neuronal-network simulation output1803.10205v1 · Johanna Senk, Corto Carde, Espen Hagen et al.2018 · 12 citationsFront. Neuroinform. 12:75 (2018)
Brain signal predictions from multi-scale networks using a linearized framework.35960767 · Hagen, Espen, Magnusson, Steinn H, Ness, Torbjørn V et al.2022 · 29 citationsPLoS computational biology. 2022;18(8):e1010353
Brain signal predictions from multi-scale networks using a linearized framework10.1101/2022.02.28.482256v3 · Hagen, E., Magnusson, S. H., Ness, T. V. et al.2022 · 29 citationsbioRxiv
Hybrid scheme for modeling local field potentials from point-neuron networks1511.01681v2 · Espen Hagen, David Dahmen, Maria L. Stavrinou et al.2015 · 105 citationsarXivon Valency
Uncovering circuit mechanisms of current sinksand sources with biophysical simulations ofprimary visual cortex10.1101/2022.02.22.481540v1 · Rimehaug, A. E., Stasik, A. J., Hagen, E. et al.2022 · 4 citationsbioRxiv
RippleNet: a Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection.33394388 · Hagen, Espen, Chambers, Anna R, Einevoll, Gaute T et al.2021 · 28 citationsNeuroinformatics. 2021;19(3):493-514
Biophysically detailed forward modeling of the neural origin of EEG and MEG signals.33075556 · Næss, Solveig, Halnes, Geir, Hagen, Espen et al.2021 · 84 citationsNeuroImage. 2021;225:117467
Multimodal Modeling of Neural Network Activity: Computing LFP, ECoG, EEG, and MEG Signals With LFPy 2.0.30618697 · Hagen, Espen, Næss, Solveig, Ness, Torbjørn V et al.2020 · 158 citationsFrontiers in neuroinformatics. 2018;12:92
Biophysical modeling of the neural origin of EEG and MEG signals10.1101/2020.07.01.181875v1 · Naess, S., Halnes, G., Hagen, E. et al.2020 · 0 citationsbioRxiv
Estimation of neural network model parameters from local field potentials (LFPs).32155141 · Skaar, Jan-Eirik W, Stasik, Alexander J, Hagen, Espen et al.2020 · 27 citationsPLoS computational biology. 2020;16(3):e1007725
RippleNet: A Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection10.1101/2020.05.11.087874v1 · Hagen, E., Chambers, A. R., Einevoll, G. T. et al.2020 · 28 citationsbioRxiv
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations.30475994 · Mäki-Marttunen, Tuomo, Krull, Florian, Bettella, Francesco et al.2020 · 42 citationsCerebral cortex (New York, N.Y. : 1991). 2019;29(2):875-891
Independent Component Analysis for Fully Automated Multi-Electrode Array Spike Sorting.30440947 · Buccino, Alessio P, Hagen, Espen, Einevoll, Gaute T et al.2019 · 18 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2018;2018:2627-2630
LFPy - multimodal modeling of extracellular neuronal recordings in Python10.1101/620286v1 · Hagen, E., Naess, S., Ness, T. V. et al.2019 · 7 citationsbioRxiv
Estimation of neural network model parameters from local field potentials (LFPs)10.1101/564765v1 · Skaar, J.-E. W., Stasik, A. J., Hagen, E. et al.2019 · 27 citationsbioRxiv
Multimodal modeling of neural network activity: computing LFP, ECoG, EEG and MEG signals with LFPy2.010.1101/281717v1 · Hagen, E., Naess, S., Ness, T. V. et al.2018 · 14 citationsbioRxiv
Focal Local Field Potential Signature of the Single-Axon Monosynaptic Thalamocortical Connection.28432143 · Hagen, Espen, Fossum, Janne C, Pettersen, Klas H et al.2017 · 33 citationsThe Journal of neuroscience : the official journal of the Society for Neuroscience. 2017;37(20):5123-5143
YASS: Yet Another Spike Sorter10.1101/151928v1 · Lee, J., Carlson, D., Shokri, H. et al.2017 · 62 citationsbioRxiv
Biophysical Network Modelling of the dLGN Circuit: Different Effects of Triadic and Axonal Inhibition on Visual Responses of Relay Cells.27203421 · Heiberg, Thomas, Hagen, Espen, Halnes, Geir et al.2017 · 16 citationsPLoS computational biology. 2016;12(5):e1004929
ViSAPy: a Python tool for biophysics-based generation of virtual spiking activity for evaluation of spike-sorting algorithms.25662445 · Hagen, Espen, Ness, Torbjørn V, Khosrowshahi, Amir et al.2016 · 65 citationsJournal of neuroscience methods. 2015;245:182-204
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