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Nicolas Spinelli

Biosensing TechniquesG-Quadruplexesaptamer graftingaptasensorbiolayer interferometrybiosensorscs.AIcyclodecapeptideDNADNAzyme

On Valency

published · living versions
W_n6rj4p5u·v1 · currentpublished
Humans Correct Their Judgments Through Debate, but Weaker AI Models Do Not
with Maria Victoria Carro, Denise Alejandra Mester, Facundo Nieto, Oscar Agustin Stanchi +12
1 version

Preprints & journals

34 papers in the corpus · 2000–2026
Humans Correct Their Judgments Through Debate, but Weaker AI Models Do Not2610.28539v1 · Maria Victoria Carro, Denise Alejandra Mester, Facundo Nieto et al.2026 · 0 citationsarXivon Valency
Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude.35983869 · Pons, Marina, Perenon, Marine, Bonnet, Hugues et al.2022 · 26 citationsThe Analyst. 2022;147(19):4197-4205
Negative SPR Signals during Low Molecular Weight Analyte Recognition.33577288 · Bonnet, H, Coche-Guérente, L, Defrancq, E et al.2021 · 42 citationsAnalytical chemistry. 2021;93(8):4134-4140
Optimization of GOPS-Based Functionalization Process and Impact of Aptamer Grafting on the Si Nanonet FET Electrical Properties as First Steps towards Thrombin Electrical Detection.32942692 · Vallejo-Perez, Monica, Ternon, Céline, Spinelli, Nicolas et al.2020 · 8 citationsNanomaterials (Basel, Switzerland). 2020;10(9)
Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry.32786219 · Vignon, Anthony, Flaget, Arthur, Michelas, Maxime et al.2021 · 26 citationsACS sensors. 2020;5(8):2326-2330
The pKa value of the proximal water molecule trans to a high-valent MnV[double bond, length as m-dash]O porphyrin: towards the control of reactivity by pH.28853461 · Saint-Germes, Laurie, Bar, Laure, Dejeu, Jérôme et al.2018 · 2 citationsDalton transactions (Cambridge, England : 2003). 2017;46(36):12088-12094
Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film.27332710 · Kazane, Imen, Gorgy, Karine, Gondran, Chantal et al.2018 · 53 citationsAnalytical chemistry. 2016;88(14):7268-73
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.26689623 · Flack, Theodore, Constantin, Thibaut, Penasse, Sylvain et al.2016 · 3 citationsChemistry (Weinheim an der Bergstrasse, Germany). 2016;22(5):1760-7
Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes.26122480 · Osypova, Alina, Thakar, Dhruv, Dejeu, Jérôme et al.2016 · 56 citationsAnalytical chemistry. 2015;87(15):7566-74
A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds.25164147 · Thomas, Baptiste, Fiore, Michele, Daskhan, Gour Chand et al.2016 · 32 citationsChemical communications (Cambridge, England). 2015;51(25):5436-9
Construction of anti-parallel G-quadruplexes through sequential templated click.25695596 · Bonnet, Romaric, Lavergne, Thomas, Gennaro, Béatrice et al.2015 · 23 citationsChemical communications (Cambridge, England). 2015;51(23):4850-3
Macrocyclic host-dye reporter for sensitive sandwich-type fluorescent aptamer sensor.25738735 · Yang, Cheng, Spinelli, Nicolas, Perrier, Sandrine et al.2015 · 36 citationsAnalytical chemistry. 2015;87(6):3139-43
Label-free photoelectrochemical detection of double-stranded HIV DNA by means of a metallointercalator-functionalized electrogenerated polymer.25263248 · Haddache, Fatima, Le Goff, Alan, Reuillard, Bertrand et al.2015 · 19 citationsChemistry (Weinheim an der Bergstrasse, Germany). 2014;20(47):15555-60
Surface-immobilized DNAzyme-type biocatalysis.24452273 · Stefan, Loic, Lavergne, Thomas, Spinelli, Nicolas et al.2014 · 14 citationsNanoscale. 2014;6(5):2693-701
High affinity glycodendrimers for the lectin LecB from Pseudomonas aeruginosa.23888914 · Berthet, Nathalie, Thomas, Baptiste, Bossu, Isabelle et al.2014 · 59 citationsBioconjugate chemistry. 2013;24(9):1598-611
Closer to nature: an ATP-driven bioinspired catalytic oxidation process.23325338 · Stefan, Loic, Duret, Damien, Spinelli, Nicolas et al.2013 · 14 citationsChemical communications (Cambridge, England). 2013;49(15):1500-2
Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels.23324407 · Moreau, Julie, Dendane, Nabil, Schöllhorn, Bernd et al.2013 · 8 citationsBioorganic & medicinal chemistry letters. 2013;23(4):955-8
Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.23254681 · Spinelli, Nicolas, Defrancq, Eric, Morvan, François2013 · 67 citationsChemical Society reviews. 2013;42(11):4557-73
Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film.22959014 · Xu, Hui, Gorgy, Karine, Gondran, Chantal et al.2013 · 77 citationsBiosensors & bioelectronics. 2013;41:90-5
Click-click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures.22576321 · Bonnet, Romaric, Murat, Pierre, Spinelli, Nicolas et al.2016 · 15 citationsChemical communications (Cambridge, England). 2012;48(48):5992-4
The use of a peptidic scaffold for the formation of stable guanine tetrads: control of a H-bonded pattern in water.21503988 · Murat, Pierre, Gennaro, Béatrice, Garcia, Julian et al.2011 · 36 citationsChemistry (Weinheim an der Bergstrasse, Germany). 2011;17(21):5791-5
Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures.20443615 · Meyer, Albert, Spinelli, Nicolas, Dumy, Pascal et al.2010 · 50 citationsThe Journal of organic chemistry. 2010;75(11):3927-30
Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.20397247 · Murat, Pierre, Bonnet, Romaric, Van der Heyden, Angéline et al.2010 · 64 citationsChemistry (Weinheim an der Bergstrasse, Germany). 2010;16(20):6106-14
Efficient conjugation of oligonucleotides through aromatic oxime formation.19857965 · Murat, Pierre, Spinelli, Nicolas, Dumy, Pascal et al.2010 · 0 citationsBioorganic & medicinal chemistry letters. 2009;19(23):6534-7
A novel conformationally constrained parallel g quadruplex.18821555 · Murat, Pierre, Cressend, Delphine, Spinelli, Nicolas et al.2009 · 49 citationsChembiochem : a European journal of chemical biology. 2008;9(16):2588-91
New solid support for the synthesis of 3'-oligonucleotide conjugates through glyoxylic oxime bond formation.17217269 · Spinelli, Nicolas, Edupuganti, Om Prakash, Defrancq, Eric et al.2007 · 19 citationsOrganic letters. 2007;9(2):219-22
Aldehydic oligonucleotide: a key intermediate for the preparation of oligonucleotide conjugates through oxime bond formation.18058501 · Spinelli, N, Singh, Y, Defrancq, E et al.2008 · 3 citationsNucleosides, nucleotides & nucleic acids. 2007;26(8-9):883-7
A novel heterobifunctional linker for facile access to bioconjugates.16557331 · Singh, Yashveer, Spinelli, Nicolas, Defrancq, Eric et al.2007 · 25 citationsOrganic & biomolecular chemistry. 2006;4(7):1413-9
The first automated synthesis of ferrocene-labelled phosphorothioate DNA probe: a new potential tool for the fabrication of DNA microarrays.16892230 · Brisset, Hugues, Navarro, Aude-Emmanuelle, Spinelli, Nicolas et al.2006 · 17 citationsBiotechnology journal. 2006;1(1):95-8
Supported synthesis of ferrocene modified oligonucleotides as new electroactive DNA probes.15109628 · Navarro, Aude-Emmanuelle, Spinelli, Nicolas, Chaix, Carole et al.2004 · 26 citationsBioorganic & medicinal chemistry letters. 2004;14(10):2439-41
Pro-oligonucleotide synthesis using allyl and allyloxycarbonyl protections: direct MALDI-TOF MS analysis on solid support.11563151 · Spinelli, N, Vasseur, J J, Hayakawa, Y et al.2002 · 5 citationsNucleosides, nucleotides & nucleic acids. 2001;20(4-7):947-50
Direct MALDI-TOF MS analysis of oligonucleotides on solid support through a photolabile linker.11563155 · Meyer, A, Spinelli, N, Brés, J C et al.2002 · 6 citationsNucleosides, nucleotides & nucleic acids. 2001;20(4-7):963-6
Analysis of solid-supported oligonucleotides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry10669882 · Meyer, Spinelli, Imbach et al.2019 · 12 citationsRapid communications in mass spectrometry : RCM. 2000;14(4):234-42
Career total: 72 works. 34 are in this corpus.

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