MS
M. Seifert
Brain NeoplasmsBreast cancerMelanomaBioinformaticsComputational systems biologyGene Expression Regulation, NeoplasticMarkov ChainsTranscriptomeβ1 integrinAlgorithms
On Valency
published · living versionsW_3kg8ctyu·v1 · currentpublished
The Astropy Project: Building an inclusive, open-science project and status of the v2.0 core package
with The Astropy Collaboration, A. M. Price-Whelan, B. M. Sipőcz, H. M. Günther +132
1 version
Preprints & journals
103 papers in the corpus · 1992–2026Collective cancer cell calcium activity drives brain metastasis10.64898/2026.05.10.723715v1 · Hebach, N. R., Olshausen, N., Schlag, J. et al.2026 · 0 citationsbioRxiv
Network-Based Prediction of Oligodendroglioma Driver Gene Candidates within the Region of the 1p/19q Co-deletion Utilizing Single-Cell Transcriptomes.42088850 · Seifert, Michael2026 · 0 citationsComputational and structural biotechnology journal. 2026;35(1):0059
[Strengthening treatment options in the care of mentally ill patients through flexible and integrated treatment for patient-centered care with a global budget - final results from the EVA64 study].42155521 · Neumann, Anne, Baum, Fabian, Kliemt, Roman et al.2026 · 1 citationPsychiatrische Praxis. 2026;53(4):171-181
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer.41527462 · Curvello, Rodrigo, Hauser, Sandra, Seifert, Michael et al.2026 · 2 citationsAdvanced science (Weinheim, Baden-Wurttemberg, Germany). 2026;13(13):e16578
Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies.41529692 · Di Donato, Nataliya, NMA Consortium, Thom, Andrew et al.2026 · 6 citationsAmerican journal of human genetics. 2026;113(2):324-341
Human fingertip regeneration follows clinical phases with distinct proteomic signatures.41193504 · Schultz, Jurek, Patel, Purva A, Aires, Rita et al.2025 · 3 citationsNPJ Regenerative medicine. 2025;10(1):51
Comparative preclinical drug response analyses of T-prolymphocytic leukemia reveal no differences between known gene expression subgroups.41146244 · Mikhaylenko, Nathan, Braun, Till, Timonen, Sanna et al.2026 · 0 citationsBiology direct. 2025;20(1):106
Single-cell transcriptome analysis suggests cells of the tumor microenvironment as a major discriminator between brain and extracranial melanoma metastases.40954493 · Grützmann, Konrad, Seifert, Michael2025 · 0 citationsBiology direct. 2025;20(1):97
Human fingertip regeneration follows clinical phases with distinct proteomic signatures, a Comprehensive MS/MS analysis10.1101/2025.06.06.25329128v1 · Schultz, J., Patel, P. A., Aires, R. et al.2025 · 0 citationsmedRxiv
A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression.40494026 · Kast, Verena J, Hauser, Sandra, Nadernezhad, Ali et al.2025 · 7 citationsBiomaterials. 2026;324:123456
A novel role of exostosin glycosyltransferase 2 (EXT2) in glioblastoma cell metabolism, radiosensitivity and ferroptosis.40234611 · Matesanz-Sánchez, Rocío, Peitzsch, Mirko, Lange, Inga et al.2025 · 10 citationsCell death and differentiation. 2025;32(9):1664-1678
HER2 and HER3 expression during neoadjuvant treatment of HER2-negative early breast cancer: potential for biomarker-driven sequencing of T-DXd and HER3-DXd.39757921 · Singer, Christian Fridolin, Jahn, Stephan Wenzel, Hlauschek, Dominik et al.2025 · 3 citationsCancer communications (London, England). 2025;45(4):428-432
Influence of histopathological changes after neoadjuvant chemotherapy on the survival of breast cancer patients.40031096 · Danzinger, Sabine, Spornberger, Verena Heiss, Vietzen, Hannes et al.2025 · 2 citationsCancer treatment and research communications. 2025;43:100886
Comparative analysis of neurofilaments and biomarkers of muscular damage in amyotrophic lateral sclerosis.39239150 · Vidovic, Maximilian, Lapp, Hanna Sophie, Weber, Constanze et al.2024 · 17 citationsBrain communications. 2024;6(5):fcae288
Genomic and biological panoramas of non-muscle actinopathies10.1101/2024.08.21.24310320v1 · Di Donato, N., Thom, A., Rump, A. et al.2024 · 4 citationsmedRxiv
Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles.38741178 · Grützmann, Konrad, Salomo, Karsten, Krüger, Alexander et al.2024 · 19 citationsBiology direct. 2024;19(1):38
Personalized identification and characterization of genome-wide gene expression differences between patient-matched intracranial and extracranial melanoma metastasis pairs.38671536 · Kraft, Theresa, Grützmann, Konrad, Meinhardt, Matthias et al.2024 · 9 citationsActa neuropathologica communications. 2024;12(1):67
Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome.38378518 · Broghammer, Felix, Korovina, Irina, Gouda, Mahesh et al.2024 · 19 citationsMolecular cancer. 2024;23(1):39
Network-based analysis of heterogeneous patient-matched brain and extracranial melanoma metastasis pairs reveals three homogeneous subgroups.38464935 · Grützmann, Konrad, Kraft, Theresa, Meinhardt, Matthias et al.2024 · 13 citationsComputational and structural biotechnology journal. 2024;23:1036-1050
β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models.38286037 · Korovina, Irina, Elser, Marc, Borodins, Olegs et al.2024 · 5 citationsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024;171:116217
Meta-analysis of expression and the targeting of cell adhesion associated genes in nine cancer types - A one research lab re-evaluation.37206618 · Borodins, Olegs, Broghammer, Felix, Seifert, Michael et al.2024 · 7 citationsComputational and structural biotechnology journal. 2023;21:2824-2836
Identification of Epigenetically Regulated Genes Distinguishing Intracranial from Extracranial Melanoma Metastases.36716920 · Westphal, Dana, Meinhardt, Matthias, Grützmann, Konrad et al.2023 · 16 citationsThe Journal of investigative dermatology. 2023;143(7):1233-1245.e17
Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases.36624125 · Kraft, Theresa, Grützmann, Konrad, Meinhardt, Matthias et al.2023 · 19 citationsScientific reports. 2023;13(1):444
Atezolizumab plus nab-paclitaxel for unresectable, locally advanced or metastatic breast cancer: real-world results from a single academic center in Austria.36289467 · Deutschmann, Christine, Bartsch, Rupert, Singer, Christian F et al.2022 · 10 citationsBMC cancer. 2022;22(1):1099
Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemia.36129940 · Mikhaylenko, Nathan, Wahnschaffe, Linus, Herling, Marco et al.2022 · 8 citationsPloS one. 2022;17(9):e0274463
MARVEL domain containing CMTM4 affects CXCR4 trafficking.36044337 · Bona, Alexandra, Seifert, Michael, Thünauer, Roland et al.2022 · 3 citationsMolecular biology of the cell. 2022;33(13):ar116
RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations.35269477 · Sidorova, Olga Alexandra, Sayed, Shady, Paszkowski-Rogacz, Maciej et al.2022 · 7 citationsCells. 2022;11(5)
Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases.35008420 · Schwarz, Annemarie, Roeder, Ingo, Seifert, Michael2022 · 8 citationsCancers. 2022;14(1)
Advanced Pathogenetic Concepts in T-Cell Prolymphocytic Leukemia and Their Translational Impact.34869023 · Braun, Till, Dechow, Annika, Friedrich, Gregor et al.2021 · 20 citationsFrontiers in oncology. 2021;11:775363
"Anemia and Response to Neoadjuvant Chemotherapy in Breast Cancer Patients".33961512 · Danzinger, Sabine, Fügerl, Alexandra, Pfeifer, Christian et al.2021 · 5 citationsCancer investigation. 2021;39(6-7):457-465
Influence of Height on Risk and Outcome of Patients with Early Breast Cancer: A Pooled Analysis of 4,925 Patients from 5 Randomized Trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG).35707180 · Gampenrieder, Simon P, Pircher, Magdalena, Fesl, Christian et al.2023 · 0 citationsBreast care (Basel, Switzerland). 2022;17(2):137-145
The clinical-phenotype continuum in DYNC1H1-related disorders-genomic profiling and proposal for a novel classification.32788638 · Becker, Lena-Luise, Dafsari, Hormos Salimi, Schallner, Jens et al.2021 · 52 citationsJournal of human genetics. 2020;65(11):1003-1017
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.32728112 · Lauber, Chris, Correia, Nádia, Trumpp, Andreas et al.2021 · 24 citationsScientific reports. 2020;10(1):12761
Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs.32604718 · Seifert, Michael, Schackert, Gabriele, Temme, Achim et al.2020 · 21 citationsCancers. 2020;12(6)
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing.32316399 · Johansson, Patricia, Klein-Hitpass, Ludger, Budeus, Bettina et al.2020 · 26 citationsCancers. 2020;12(4)
Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.31875560 · Kolbe, Erik, Aleithe, Susanne, Rennert, Christiane et al.2020 · 22 citationsCell reports. 2019;29(13):4553-4567.e7
Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin.31888244 · Biedermann, Julia, Preussler, Matthias, Conde, Marina et al.2020 · 34 citationsCancers. 2019;11(12)
Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse.31682594 · Seifert, Michael, Peitzsch, Claudia, Gorodetska, Ielizaveta et al.2020 · 67 citationsPLoS computational biology. 2019;15(11):e1007460
Stromal coexpression of uPA/PAI-1 protein predicts poor disease outcome in endocrine-treated postmenopausal patients with receptor-positive early breast cancer.31132475 · Singer, C F, Filipits, M, Jahn, S W et al.2020 · 12 citationsBreast (Edinburgh, Scotland). 2019;46:101-107
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples.31029168 · Zakrzewski, Falk, Gieldon, Laura, Rump, Andreas et al.2019 · 37 citationsBMC cancer. 2019;19(1):396
Multi-omic measurements of heterogeneity in HeLa cells across laboratories.30778230 · Liu, Yansheng, Mi, Yang, Mueller, Torsten et al.2019 · 335 citationsNature biotechnology. 2019;37(3):314-322
Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses.30452944 · Lauber, Chris, Seifert, Michael, Bartenschlager, Ralf et al.2019 · 29 citationsVirus research. 2019;260:38-48
Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion.29890994 · Gladitz, Josef, Klink, Barbara, Seifert, Michael2019 · 34 citationsActa neuropathologica communications. 2018;6(1):49
Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma.29844871 · Mäder, Lisa, Blank, Anna E, Capper, David et al.2019 · 19 citationsOncotarget. 2018;9(35):24041-24053
Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results10.1101/307421v1 · Liu, Y., Mi, Y., Mueller, T. et al.2018 · 8 citationsbioRxiv
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups.29631562 · Lauber, Chris, Klink, Barbara, Seifert, Michael2018 · 22 citationsBMC cancer. 2018;18(1):399
Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition.29719593 · Klapproth, Erik, Dickreuter, Ellen, Zakrzewski, Falk et al.2023 · 19 citationsOncotarget. 2018;9(26):18099-18114
regNet: an R package for network-based propagation of gene expression alterations.28968690 · Seifert, Michael, Beyer, Andreas2020 · 13 citationsBioinformatics (Oxford, England). 2018;34(2):308-311
The biology and mathematical modelling of glioma invasion: a review.29118112 · Alfonso, J C L, Talkenberger, K, Seifert, M et al.2018 · 211 citationsJournal of the Royal Society, Interface. 2017;14(136)
Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting.28514757 · Vehlow, Anne, Klapproth, Erik, Storch, Katja et al.2018 · 35 citationsOncotarget. 2017;8(30):49224-49237
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