AP
Alexandre Prat
Multiple Sclerosismultiple sclerosisMultiple sclerosisMultiple Sclerosis, Relapsing-RemittingDisease ProgressionEncephalomyelitis, Autoimmune, ExperimentalMultiple Sclerosis, Chronic ProgressiveneuroscienceAstrocytesMicroglia
On Valency
published · living versionsW_894d8afa·v1 · currentpublished
Longitudinal tracking of multiple sclerosis lesions in the spinal cord: A validation study
with Pierre-Louis Benveniste, Julian McGinnis, Shannon Kolind, Larry D. Lynd +9
1 version
Preprints & journals
315 papers in the corpus · 1989–2026Periventricular gradient pathology is linked to ependymal reactivity and cell adhesion disruption in multiple sclerosis.42881221 · Groh, Adam M R, Afanasiev, Elia, Thevakumaran, Risavarshni et al.2026 · 0 citationsNature neuroscience. 2026
Comparative effectiveness of ofatumumab and ocrelizumab in relapsing multiple sclerosis: a target trial emulation using multinational registry data.42601218 · Zhu, Chao, Vukusic, Sandra, Kalincik, Tomas et al.2026 · 0 citationsJournal of neurology, neurosurgery, and psychiatry. 2026;97(11):982-991
Longitudinal tracking of multiple sclerosis lesions in the spinal cord: A validation study2609.09424v1 · Pierre-Louis Benveniste, Julian McGinnis, Shannon Kolind et al.2026 · 0 citationsarXivon Valency
Pathogenic T-bet+ memory B cells worsen multiple sclerosis through myeloid cell activation10.64898/2026.09.01.748682v1 · Jain, R. W., Goiko, M., Mendes, A. et al.2026 · 0 citationsbioRxiv
Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria.42426222 · Oh, Jiwon, Barkhof, Frederik, Bar-Or, Amit et al.2026 · 1 citationNature medicine. 2026;32(9):3115-3119
Comparative effectiveness of ocrelizumab in subgroups of patients with multiple sclerosis: a multi-registry observational cohort study.42161588 · Roos, Izanne, Sharmin, Sifat, Horakova, Dana et al.2026 · 0 citationsJournal of neurology, neurosurgery, and psychiatry. 2026;97(9):763-773
Antigen presentation by CD40+MHC-II+ astrocytes promotes CNS autoimmunity.42557325 · Lee, Joon-Hyuk, Li, Zhaorong, Soto, Joselyn S et al.2026 · 2 citationsNature. 2026;657(8132):755-764
Long-term efficacy of cladribine tablets: Results from the MAGNIFY-MS Extension study.42548205 · De Stefano, Nicola, Vermersch, Patrick, Wiendl, Heinz et al.2026 · 1 citationMultiple sclerosis (Houndmills, Basingstoke, England). 2026:13524585261467624
Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis.41277219 · Bigotte, Maxime, Groh, Adam M R, Afanasiev, Elia et al.2026 · 4 citationsBrain : a journal of neurology. 2026;149(8):2654-2667
Multiple sclerosis outcomes after cancer diagnosis in people with recorded chemotherapy exposure: A real-world MSBase study.42543909 · Nesbitt, Cassie, Sanfilippo, Paul, Zhu, Chao et al.2026 · 0 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2026;32(10):1083-1097
Single-cell transcriptomic analysis reveals age-related remodeling of brain endothelial cells.42571539 · Nguyen, Hai Duc, Siddiqui, Summer, Bohannon, Diana G et al.2026 · 0 citationsAging brain. 2026;10:100164
Treatment escalation after clinically silent MRI lesions in relapsing-remitting multiple sclerosis.42496160 · Daruwalla, Cyrus, Kremler, Courtney, Patti, Francesco et al.2026 · 0 citationsBrain : a journal of neurology. 2026
Causal effects of multiple sclerosis therapies in left-truncated registry data.42479470 · Haile, Dagmawi Chilot, Diouf, Ibrahima, Ozakbas, Serkan et al.2026 · 0 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2026;32(10):1052-1068
Grey matter degeneration during multiple sclerosis is linked to activation of neuronal necroptosis by oxidized phosphatidylcholines.42427876 · Yu, Ruoqi, Park, Jian, Ain, Qurat Ul et al.2026 · 0 citationsResearch square. 2026
Cerebellar magnetization transfer ratio and its relationship to clinical outcomes in radiologically isolated syndrome and multiple sclerosis.42334399 · Lee, Lisa Eunyoung, Khoury, Marc, Churchill, Nathan et al.2026 · 0 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2026:13524585261450926
Myelin damage in radiologically isolated syndrome is associated with decreased processing speed.42153200 · Kalau, Olivia, Johnson, Poljanka, Oh, Jiwon et al.2026 · 0 citationsMultiple sclerosis journal - experimental, translational and clinical. 2026;12(2):20552173261446217
Discrepancy between subjective and objective cognitive function in multiple sclerosis and association with mood, fatigue, and pain.42145652 · Farah, Nour, Charbonneau, Simon, Morrow, Sarah A et al.2026 · 2 citationsMultiple sclerosis journal - experimental, translational and clinical. 2026;12(2):20552173261449673
Generalizable spinal cord multiple sclerosis lesion segmentation across MRI contrasts, protocols, and centers.42028790 · Benveniste, Pierre-Louis, Létourneau-Guillon, Laurent, Araujo, David et al.2026 · 0 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2026;32(6):598-613
A plain language summary on clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS study.41943490 · Schmierer, Klaus, Wiendl, Heinz, Barkhof, Frederik et al.2026 · 0 citationsNeurodegenerative disease management. 2026:1-11
Preserving Neurological Function in People at High and Low Risk of Aggressive Multiple Sclerosis: An Observational Cohort Study.41935174 · Roos, Izanne, Sharmin, Sifat, Ozakbas, Serkan et al.2026 · 1 citationCNS drugs. 2026;40(7):1011-1025
Multiple sclerosis disability progression and predictors: A retrospective cohort study over five decades from a Canadian registry.41781303 · Quevillon, T, Despault, P-O, Duquette, P et al.2026 · 1 citationRevue neurologique. 2026;182(4):301-311
Age and Maturation Stage Linked Consequences of Fibrinogen on Human Oligodendroglia.41866764 · Blaszczyk, Gabriela J, Weng, Chao, Mohammadnia, Abdulshakour et al.2026 · 4 citationsJournal of neuroscience research. 2026;104(3):e70120
Effect of late-onset on multiple sclerosis phenotype and outcome: evidence from a multi-national registry.41634506 · Souissi, Amira, Patti, Francesco, Spelman, Tim et al.2026 · 3 citationsJournal of neurology. 2026;273(2):114
Monitoring morphometric drift in lifelong learning segmentation of the spinal cord.41585468 · Naga Karthik, Enamundram, Bédard, Sandrine, Valošek, Jan et al.2026 · 3 citationsImaging neuroscience (Cambridge, Mass.). 2026;4
Managing reactivation of multiple sclerosis during treatment with natalizumab.41420376 · Lizak, Nathaniel, Sharmin, Sifat, Horáková, Dana et al.2026 · 1 citationMultiple sclerosis (Houndmills, Basingstoke, England). 2026;32(1):121-133
Moderate-high efficacy disease-modifying therapies reduce relapse risk in late-onset multiple sclerosis.41161724 · Foong, Yi Chao, Merlo, Daniel, Gresle, Melissa et al.2025 · 5 citationsJournal of neurology, neurosurgery, and psychiatry. 2025;97(1):50-58
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling.41326786 · Yu, Ruoqi, Lozinski, Brian M, Seifert, Ally et al.2026 · 8 citationsNature neuroscience. 2026;29(1):67-80
Bruton's tyrosine kinase inhibitors rescue neuronal impairment caused by B cell-mediated lymphotoxin-α release.41160670 · Shin, Josef, Götz, Paul, Sharif, Nesrin et al.2025 · 3 citationsScience translational medicine. 2025;17(822):eadx2652
Disease course after pregnancy in women with progressive multiple sclerosis symptoms.40974262 · Shipley, Jessica, Beadnall, Heidi N, Sanfilippo, Paul G et al.2025 · 2 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2025;31(12):1439-1451
Machine learning using clinical variables to screen for depression and anxiety in people with early multiple sclerosis.40975017 · Phillips, Braxton, Morrow, Sarah A, Singh, Harasees et al.2025 · 3 citationsMultiple sclerosis and related disorders. 2025;104:106761
Pregnancy-Related Disease Outcomes in Women With Moderate to Severe Multiple Sclerosis Disability.40952740 · Shipley, Jessica, Beadnall, Heidi N, Sanfilippo, Paul G et al.2025 · 6 citationsJAMA network open. 2025;8(9):e2531581
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.40858938 · Lee, Hong-Gyun, Rone, Joseph M, Li, Zhaorong et al.2026 · 1 citationNature. 2025;645(8081):E5
Clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS Study.40756532 · Schmierer, Klaus, Wiendl, Heinz, Barkhof, Frederik et al.2025 · 11 citationsTherapeutic advances in neurological disorders. 2025;18:17562864251351760
Personalized federated learning for predicting disability progression in multiple sclerosis using real-world routine clinical data.40707601 · Pirmani, Ashkan, De Brouwer, Edward, Arany, Ádám et al.2025 · 10 citationsNPJ digital medicine. 2025;8(1):478
Four years on: Pregnancy and birth outcomes reported in the MSBase pregnancy, neonatal outcomes, and Women's Health Registry (2020-2024).40621862 · Jokubaitis, Vilija G, Alroughani, Raed, Altintas, Ayse et al.2025 · 2 citationsMultiple sclerosis (Houndmills, Basingstoke, England). 2025;31(9):1088-1101
Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis pathophysiology10.1101/2025.07.06.663378v2 · Bigotte, M., Groh, A. M. R., Afanasiev, E. et al.2025 · 1 citationbioRxiv
Summary of Research: Blood Biomarker Dynamics in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study.40614039 · Wiendl, Heinz, Barkhof, Frederik, Montalban, Xavier et al.2025 · 0 citationsNeurology and therapy. 2025;14(5):1743-1746
Peripheral HLA-DRhiCD141+ Classical Monocytes Predict Relapse Risk and Worsening in Multiple Sclerosis.40609052 · Thai, Karine, Rebillard, Rose-Marie, Klement, Wendy et al.2025 · 0 citationsNeurology(R) neuroimmunology & neuroinflammation. 2025;12(5):e200426
Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis.40583289 · Lee, Lisa Eunyoung, Cohen-Adad, Julien, Vavasour, Irene M et al.2025 · 2 citationsAnnals of clinical and translational neurology. 2025;12(9):1794-1804
First-Line Use of Higher-Efficacy Disease-Modifying Therapies in Multiple Sclerosis: Canadian Consensus Recommendations.40485478 · Freedman, Mark S, Clift, Fraser, Devonshire, Virginia et al.2025 · 3 citationsThe Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2025:1-10
Detection of astrocyte epigenetic memory in in vitro systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples10.1101/2025.05.30.657119v1 · Quintana, F. J., Li, Z., Faust Akl, C. et al.2025 · 2 citationsbioRxiv
Standardized Definition of Progression Independent of Relapse Activity (PIRA) in Relapsing-Remitting Multiple Sclerosis.40227706 · Müller, Jannis, Sharmin, Sifat, Lorscheider, Johannes et al.2025 · 62 citationsJAMA neurology. 2025;82(6):614-625
Bruton Tyrosine Kinase in Lesions of Multiple Sclerosis and 3 of Its Models.40440578 · Li, Cenxiao, Morch, Marlene T, Gorter, Rianne et al.2025 · 6 citationsNeurology(R) neuroimmunology & neuroinflammation. 2025;12(4):e200413
Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network.39643429 · Lorscheider, Johannes, Signori, Alessio, Subramaniam, Suvitha et al.2025 · 4 citationsJournal of neurology, neurosurgery, and psychiatry. 2025;96(6):606-615
The Blood-Brain Barrier: Composition, Properties, and Roles in Brain Health.38951020 · Lacoste, Baptiste, Prat, Alexandre, Freitas-Andrade, Moises et al.2025 · 75 citationsCold Spring Harbor perspectives in biology. 2025;17(5)
Monitoring morphometric drift in lifelong learning segmentation of the spinal cord.40735109 · Karthik, Enamundram Naga, Bédard, Sandrine, Valošek, Jan et al.2025 · 0 citationsArXiv. 2025
Exploration of individual beta cell function over time in vivo: effects of hyperglycemia and glucagon-like peptide-1 receptor (GLP1R) agonism.40236128 · Delgadillo-Silva, Luis Fernando, Salazar, Shadai, Lopez Noriega, Livia et al.2025 · 0 citationsbioRxiv : the preprint server for biology. 2025
Corrigendum: Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.40109340 · Wiendl, Heinz, Barkhof, Frederik, Montalban, Xavier et al.2025 · 1 citationFrontiers in immunology. 2025;16:1571978
CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model.40033124 · Kadowaki, Atsushi, Wheeler, Michael A, Li, Zhaorong et al.2025 · 29 citationsNature neuroscience. 2025;28(3):470-486
First-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis.39965993 · Toscano, Simona, Spelman, Tim, Ozakbas, Serkan et al.2025 · 7 citationsNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2025;22(2):e00552
Career total: 542 works. 315 are in this corpus.Showing the 50 most recent.
Profile built from the corpus for this byline.
Author records are still filling in while the Hub is in alpha. If this is your page, you'll be able to claim it soon. Spot a mistake? Tell us.