DR
David J. Reiss
astro-phAlgorithmsGene Regulatory NetworksMyopathies, Structural, CongenitalSoftwaresystems biologyDynamin IIGene Expression Regulation, BacterialModels, Geneticastro-ph.IM
On Valency
published · living versionsW_pqbd2xc3·v1 · currentpublished
The LSST Data Management System
with Mario Jurić, Jeffrey Kantor, K-T Lim, Robert H. Lupton +60
1 version
Preprints & journals
91 papers in the corpus · 1980–2026The Vera C. Rubin Observatory Data Preview 12603.23786v1 · Tatiana Acero Cuellar, Emily Acosta, Christina L Adair et al.2026 · 5 citationsarXiv
Combining dynamin 2 myopathy and neuropathy mutations rescues both phenotypes.40393994 · Goret, Marie, Edelweiss, Evelina, Jehl, Jérémy et al.2025 · 8 citationsNature communications. 2025;16(1):4667
Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms.39915477 · Sivakumar, Shivan, Jainarayanan, Ashwin, Arbe-Barnes, Edward et al.2025 · 59 citationsNature communications. 2025;16(1):1397
Transcriptomic characterization of postnatal muscle maturation.39945189 · Simon, Alix, Djeddi, Sarah, Bournon, Pauline et al.2025 · 5 citationsDisease models & mechanisms. 2025;18(2)
Potential compensatory mechanisms preserving cardiac function in myotubular myopathy.39625536 · Simon, Alix, Diedhiou, Nadège, Reiss, David et al.2024 · 6 citationsCellular and molecular life sciences : CMLS. 2024;81(1):476
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function.39446948 · Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E et al.2024 · 61 citationsScience (New York, N.Y.). 2024;386(6720):eadk9167
High-plex imaging and cellular neighborhood spatial analysis reveals multiple immune escape and suppression patterns in diffuse large B-cell lymphoma.38575670 · Reiss, David J, Nakayama, Yumi, Weng, Andrew P et al.2024 · 11 citationsLeukemia. 2024;38(5):1164-1168
[PI3KC2β: A promising therapeutic target in myotubular myopathy].37975768 · Goret, Marie, Massana-Muñoz, Xènia, Nattarayan, Vasugi et al.2023 · 0 citationsMedecine sciences : M/S. 2023;39 Hors série n° 1:32-36
MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance.37542718 · Peterson, Eliza J R, Brooks, Aaron N, Reiss, David J et al.2023 · 33 citationsCell reports. 2023;42(8):112875
Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies.36562127 · Gineste, Charlotte, Simon, Alix, Braun, Marie et al.2023 · 17 citationsBrain : a journal of neurology. 2023;146(7):3029-3048
Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice.36943412 · Massana-Muñoz, Xènia, Goret, Marie, Nattarayan, Vasugi et al.2023 · 16 citationsJCI insight. 2023;8(9)
Exploration of Tumor Biopsy Gene Signatures to Understand the Role of the Tumor Microenvironment in Outcomes to Lisocabtagene Maraleucel.36595660 · Olson, N Eric, Ragan, Seamus P, Reiss, David J et al.2023 · 16 citationsMolecular cancer therapeutics. 2023;22(3):406-418
Zn2+ inhibits spatial memory and hippocampal place cell representation through high-affinity binding to the NMDA receptor GluN2A subunit.36325055 · Sikora, Joanna, Di Bisceglie Caballero, Sonia, Reiss, David et al.2022 · 5 citationsiScience. 2022;25(11):105355
Delta Opioid Receptor in Astrocytes Contributes to Neuropathic Cold Pain and Analgesic Tolerance in Female Mice.34602984 · Reiss, David, Maurin, Hervé, Audouard, Emilie et al.2023 · 17 citationsFrontiers in cellular neuroscience. 2021;15:745178
Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes.34371181 · Silva-Rojas, Roberto, Nattarayan, Vasugi, Jaque-Fernandez, Francisco et al.2022 · 39 citationsMolecular therapy : the journal of the American Society of Gene Therapy. 2022;30(2):868-880
Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma.34183722 · Wall, Matthew A, Turkarslan, Serdar, Wu, Wei-Ju et al.2021 · 10 citationsNPJ precision oncology. 2021;5(1):60
Multi-omics comparisons of different forms of centronuclear myopathies and the effects of several therapeutic strategies.33940157 · Djeddi, Sarah, Reiss, David, Menuet, Alexia et al.2022 · 21 citationsMolecular therapy : the journal of the American Society of Gene Therapy. 2021;29(8):2514-2534
MtrA regulation of essential peptidoglycan cleavage in Mycobacterium tuberculosis during infection10.1101/2021.02.25.432019v1 · Peterson, E. J. R., Brooks, A. N., Reiss, D. J. et al.2021 · 4 citationsbioRxiv
A generalizable data-driven multicellular model of pancreatic ductal adenocarcinoma.32696951 · Aguilar, Boris, Gibbs, David L, Reiss, David J et al.2021 · 25 citationsGigaScience. 2020;9(7)
Open-label, Phase I Study of Nivolumab Combined with nab-Paclitaxel Plus Gemcitabine in Advanced Pancreatic Cancer.32554514 · Wainberg, Zev A, Hochster, Howard S, Kim, Edward J et al.2021 · 158 citationsClinical cancer research : an official journal of the American Association for Cancer Research. 2020;26(18):4814-4822
Mu opioid receptor in microglia contributes to morphine analgesic tolerance, hyperalgesia, and withdrawal in mice.32253777 · Reiss, David, Maduna, Tando, Maurin, Hervé et al.2022 · 63 citationsJournal of neuroscience research. 2022;100(1):203-219
ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells.31743345 · Danziger, Samuel A, Gibbs, David L, Shmulevich, Ilya et al.2020 · 38 citationsPloS one. 2019;14(11):e0224693
Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice.30662412 · Maduna, Tando, Audouard, Emilie, Dembélé, Doulaye et al.2020 · 78 citationsFrontiers in psychiatry. 2018;9:726
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.29649744 · Ahonen, Tiina J, Rinne, Maiju, Grutschreiber, Peter et al.2018 · 3 citationsEuropean journal of medicinal chemistry. 2018;151:495-507
Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide.28871199 · Roeckel, Laurie-Anne, Utard, Valérie, Reiss, David et al.2019 · 95 citationsScientific reports. 2017;7(1):10406
Mechanism for microbial population collapse in a fluctuating resource environment.28320772 · Turkarslan, Serdar, Raman, Arjun V, Thompson, Anne W et al.2017 · 27 citationsMolecular systems biology. 2017;13(3):919
Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis.27426982 · Plaisier, Christopher L, O'Brien, Sofie, Bernard, Brady et al.2018 · 125 citationsCell systems. 2016;3(2):172-186
The LSST Data Management System1512.07914v1 · Mario Juri'c, Jeffrey Kantor, K-T Lim et al.2015 · 99 citationsarXivon Valency
Transcriptional program for nitrogen starvation-induced lipid accumulation in Chlamydomonas reinhardtii.26633994 · López García de Lomana, Adrián, Schäuble, Sascha, Valenzuela, Jacob et al.2015 · 80 citationsBiotechnology for biofuels. 2015;8:207
cMonkey2: Automated, systematic, integrated detection of co-regulated gene modules for any organism.25873626 · Reiss, David J, Plaisier, Christopher L, Wu, Wei-Ju et al.2015 · 45 citationsNucleic acids research. 2015;43(13):e87
A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis.25977815 · Turkarslan, Serdar, Peterson, Eliza J R, Rustad, Tige R et al.2015 · 56 citationsScientific data. 2015;2:150010
The DNA-binding network of Mycobacterium tuberculosis.25581030 · Minch, Kyle J, Rustad, Tige R, Peterson, Eliza J R et al.2016 · 223 citationsNature communications. 2015;6:5829
Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions.25881257 · Danziger, Samuel A, Reiss, David J, Ratushny, Alexander V et al.2016 · 5 citationsBMC systems biology. 2015;9 Suppl 2:S1
Evolution of context dependent regulation by expansion of feast/famine regulatory proteins.25394904 · Plaisier, Christopher L, Lo, Fang-Yin, Ashworth, Justin et al.2015 · 25 citationsBMC systems biology. 2014;8:122
Inference of expanded Lrp-like feast/famine transcription factor targets in a non-model organism using protein structure-based prediction.25255272 · Ashworth, Justin, Plaisier, Christopher L, Lo, Fang Yin et al.2015 · 6 citationsPloS one. 2014;9(9):e107863
A high-resolution network model for global gene regulation in Mycobacterium tuberculosis.25232098 · Peterson, Eliza J R, Reiss, David J, Turkarslan, Serdar et al.2015 · 63 citationsNucleic acids research. 2014;42(18):11291-303
A system-level model for the microbial regulatory genome.25028489 · Brooks, Aaron N, Reiss, David J, Allard, Antoine et al.2015 · 68 citationsMolecular systems biology. 2014;10:740
New automated procedure to assess context recognition memory in mice.24770677 · Reiss, David, Walter, Ondine, Bourgoin, Lucie et al.2015 · 8 citationsPsychopharmacology. 2014;231(22):4337-47
Network portal: a database for storage, analysis and visualization of biological networks.24271392 · Turkarslan, Serdar, Wurtmann, Elisabeth J, Wu, Wei-Ju et al.2014 · 22 citationsNucleic acids research. 2014;42(Database issue):D184-90
Molecular mechanisms of system responses to novel stimuli are predictable from public data.24185701 · Danziger, Samuel A, Ratushny, Alexander V, Smith, Jennifer J et al.2014 · 28 citationsNucleic acids research. 2014;42(3):1442-60
A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen.24089473 · Yoon, Sung Ho, Turkarslan, Serdar, Reiss, David J et al.2014 · 36 citationsGenome research. 2013;23(11):1839-51
Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice.24069332 · Weibel, Raphaël, Reiss, David, Karchewski, Laurie et al.2014 · 134 citationsPloS one. 2013;8(9):e74706
Global analysis of mRNA stability in Mycobacterium tuberculosis.23125364 · Rustad, Tige R, Minch, Kyle J, Brabant, William et al.2013 · 89 citationsNucleic acids research. 2013;41(1):509-17
The nociceptin orphanin FQ peptide receptor agonist, Ro64-6198, impairs recognition memory formation through interaction with glutamatergic but not cholinergic receptor antagonists.22982481 · Reiss, David, Prinssen, Eric P, Wichmann, Jürgen et al.2013 · 10 citationsNeurobiology of learning and memory. 2012;98(3):254-60
δ-Opioid mechanisms for ADL5747 and ADL5859 effects in mice: analgesia, locomotion, and receptor internalization.22700431 · Nozaki, Chihiro, Le Bourdonnec, Bertrand, Reiss, David et al.2013 · 77 citationsThe Journal of pharmacology and experimental therapeutics. 2012;342(3):799-807
Niche adaptation by expansion and reprogramming of general transcription factors.22108796 · Turkarslan, Serdar, Reiss, David J, Gibbins, Goodwin et al.2012 · 42 citationsMolecular systems biology. 2011;7:554
Influence of endogenous opioid systems on T lymphocytes as assessed by the knockout of mu, delta and kappa opioid receptors.21938479 · Karaji, Ali G, Reiss, David, Matifas, Audrey et al.2012 · 16 citationsJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2011;6(4):608-16
Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.21881568 · Ces, Aurelia, Reiss, David, Walter, Ondine et al.2012 · 15 citationsNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2012;37(2):378-89
Parallel evolution of transcriptome architecture during genome reorganization.21750103 · Yoon, Sung Ho, Reiss, David J, Bare, J Christopher et al.2012 · 56 citationsGenome research. 2011;21(11):1892-904
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit.21725314 · Nozaki, Chihiro, Vergnano, Angela Maria, Filliol, Dominique et al.2011 · 136 citationsNature neuroscience. 2011;14(8):1017-22
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