MG
Meng Gao
intrinsically disordered proteinsbinding mechanismIntrinsically Disordered ProteinsProtein aggregationProtein FoldingAntineoplastic AgentsColorectal cancerColorectal Neoplasmsfuzzy interactionMolecular Dynamics Simulation
On Valency
published · living versionsW_qspcx4nn·v2 · currentpublished
Quantum-accurate atomistic modeling of enzyme catalysis using a machine learned potential
with Armin Shayesteh Zadeh, Aniruddha Seal, Siva Dasetty, Siddarth K. Achar +8
2 versions
Preprints & journals
35 papers in the corpus · 2010–2026ShenqiYichang decoction enhances colorectal cancer immune efficacy via IDO1 mediated reduction of Treg infiltration.42869393 · Yang, Yunhe, Li, Lingchang, Fang, Yuxi et al.2026 · 0 citationsJournal of ethnopharmacology. 2026;374(Pt 3):122432
Ovarian tumor domain-containing protein 1 deficiency attenuates metabolic dysfunction-associated steatotic liver disease by promoting the ubiquitination of HSP90α in hepatocytes.42763838 · Huang, Mei-Qin, Wei, Si-Yi, Li, Meng-Zhe et al.2026 · 0 citationsMolecular biomedicine. 2026;7(1)
Quantum-accurate atomistic modeling of enzyme catalysis using a machine learned potential2609.09293v2 · Meng Gao, Armin Shayesteh Zadeh, Aniruddha Seal et al.2026 · 0 citationsarXivon Valency
Speculative Sampling For Faster Molecular Dynamics2606.02455v1 · Arthur Kosmala, Stephan Gunnemann, Meng Gao et al.2026 · 0 citationsarXiv
A non-canonical aryl hydrocarbon receptor pathway authorizes and safeguards clinical-scale expansion of functional human endothelial cells.41087734 · Lin, Yang, Geng, Fuqiang, Shieh, Jae-Hung et al.2025 · 2 citationsNature cardiovascular research. 2025;4(10):1329-1344
USP19 deficiency enhances T-cell-mediated antitumor immunity by promoting PD-L1 degradation in colorectal cancer.40020887 · Shi, Feng, Li, Guang-Jing, Liu, Yi et al.2025 · 16 citationsPharmacological research. 2025;214:107668
VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy.39978443 · Wu, Yu-Tong, Gao, Meng, Cheng, Kun-Yang et al.2025 · 3 citationsBiochimica et biophysica acta. Molecular basis of disease. 2025;1871(4):167729
Corrigendum to "In vitro characterization and molecular dynamics simulation reveal mechanism of 14-3-3ζ regulated phase separation of the tau protein" [Int. J. Biol. Macromol. 208 (2022) 1072-1081].39626612 · Han, Yue, Ye, Haiqiong, Li, Ping et al.2024 · 0 citationsInternational journal of biological macromolecules. 2025;284(Pt 2):138203
Shengqiyichang decoction regulates antitumor immunity in colorectal cancer by downregulating lymphocyte antigen 6 family member G6D via the protein kinase B/p38 mitogen-activated protein kinase signaling pathway.39524806 · Luo, Run Xing, Li, Huai Liang, Jia, Yu Xiang et al.2024 · 3 citationsHeliyon. 2024;10(21):e39071
Coordination of transcription-coupled repair and repair-independent release of stalled RNA polymerase II in response to transcription-blocking lesions10.1101/2024.07.07.602436v1 · Zhu, Y., Zhang, X., Gao, M. et al.2024 · 1 citationbioRxiv
LncRNA XIST promotes bladder cancer progression by modulating miR-129-5p/TNFSF10 axis.38446257 · Kong, Yu-Lin, Wang, Hui-Dan, Gao, Meng et al.2024 · 9 citationsDiscover oncology. 2024;15(1):65
Liquid - liquid phase separation of tau: Driving forces, regulation, and biological implications.37230179 · Li, Ping, Chen, Jingxin, Wang, Xi et al.2023 · 30 citationsNeurobiology of disease. 2023;183:106167
Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer.37037136 · Hu, Shihe, Jiang, Cuihua, Gao, Meng et al.2023 · 10 citationsEuropean journal of medicinal chemistry. 2023;253:115334
(-)-Epigallocatechin-3-gallate, a Polyphenol from Green Tea, Regulates the Liquid-Liquid Phase Separation of Alzheimer's-Related Protein Tau.36688583 · Chen, Jingxin, Ma, Wanyao, Yu, Jiangchuan et al.2023 · 20 citationsJournal of agricultural and food chemistry. 2023;71(4):1982-1993
Premature termination codon: a tunable protein translation approach.35796100 · Cheng, Xiyao, Zhou, Ting, Yang, Zixin et al.2022 · 6 citationsBioTechniques. 2022;73(2):80-89
In vitro characterization and molecular dynamics simulation reveal mechanism of 14-3-3ζ regulated phase separation of the tau protein.35381286 · Han, Yue, Ye, Haiqiong, Li, Ping et al.2022 · 15 citationsInternational journal of biological macromolecules. 2022;208:1072-1081
Leveraging the multivalent p53 peptide-MdmX interaction to guide the improvement of small molecule inhibitors.35228542 · Cheng, Xiyao, Chen, Rong, Zhou, Ting et al.2022 · 21 citationsNature communications. 2022;13(1):1087
14-3-3 Proteins are Potential Regulators of Liquid-Liquid Phase Separation.35142991 · Huang, Xianlong, Zheng, Zhiwen, Wu, Yixin et al.2022 · 34 citationsCell biochemistry and biophysics. 2022;80(2):277-293
Introducing intrinsic disorder reduces electrostatic steering in protein-protein interactions.34214536 · Gao, Meng, Han, Yue, Zeng, Yifan et al.2021 · 4 citationsBiophysical journal. 2021;120(15):2998-3007
The structure and phase of tau: from monomer to amyloid filament.33078207 · Zeng, Yifan, Yang, Jing, Zhang, Bailing et al.2021 · 42 citationsCellular and molecular life sciences : CMLS. 2021;78(5):1873-1886
Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters.32410006 · Gao, Meng, Huang, Jian, Jiang, Xin et al.2021 · 25 citationsProtein & cell. 2020;11(6):446-451
Anticancer Actions of Azurin and Its Derived Peptide p28.32180097 · Huang, Fan, Shu, Qianhui, Qin, Zhaojie et al.2020 · 41 citationsThe protein journal. 2020;39(2):182-189
Electrostatic interactions in molecular recognition of intrinsically disordered proteins.31709918 · Yang, Jing, Zeng, Yifan, Liu, Yunfei et al.2021 · 30 citationsJournal of biomolecular structure & dynamics. 2020;38(16):4883-4894
Features of molecular recognition of intrinsically disordered proteins via coupled folding and binding.31441158 · Yang, Jing, Gao, Meng, Xiong, Junwen et al.2020 · 84 citationsProtein science : a publication of the Protein Society. 2019;28(11):1952-1965
Intrinsically Disordered Transactivation Domains Bind to TAZ1 Domain of CBP via Diverse Mechanisms.31521329 · Gao, Meng, Yang, Jing, Liu, Sen et al.2020 · 11 citationsBiophysical journal. 2019;117(7):1301-1310
Recombinant Butelase-Mediated Cyclization of the p53-Binding Domain of the Oncoprotein MdmX-Stabilized Protein Conformation as a Promising Model for Structural Investigation.31187974 · Pi, Ni, Gao, Meng, Cheng, Xiyao et al.2020 · 28 citationsBiochemistry. 2019;58(27):3005-3015
The influence of intrinsic folding mechanism of an unfolded protein on the coupled folding-binding process during target recognition.30520528 · Xiong, Junwen, Gao, Meng, Zhou, Jingjing et al.2020 · 2 citationsProteins. 2019;87(4):265-275
Exploring the Roles of Proline in Three-Dimensional Domain Swapping from Structure Analysis and Molecular Dynamics Simulations.29119487 · Huang, Yongqi, Gao, Meng, Su, Zhengding2018 · 12 citationsThe protein journal. 2018;37(1):13-20
Bacterial cupredoxin azurin hijacks cellular signaling networks: Protein-protein interactions and cancer therapy.28960574 · Gao, Meng, Zhou, Jingjing, Su, Zhengding et al.2017 · 62 citationsProtein science : a publication of the Protein Society. 2017;26(12):2334-2341
Deciphering the promiscuous interactions between intrinsically disordered transactivation domains and the KIX domain.28786199 · Huang, Yongqi, Gao, Meng, Yang, Fei et al.2017 · 9 citationsProteins. 2017;85(11):2088-2095
Exploring the sequence-structure-function relationship for the intrinsically disordered βγ-crystallin Hahellin.28393629 · Gao, Meng, Yang, Fei, Zhang, Lei et al.2019 · 4 citationsJournal of biomolecular structure & dynamics. 2018;36(5):1171-1181
Targeting protein-protein interfaces using macrocyclic peptides.25664609 · Gao, Meng, Cheng, Kui, Yin, Hang2016 · 73 citationsBiopolymers. 2015;104(4):310-6
Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response.25400297 · Gao, Meng, London, Nir, Cheng, Kui et al.2019 · 17 citationsTetrahedron. 2014;70(42):7664-7668
Key residues that play a critical role in urea-induced lysozyme unfolding.21053934 · Gao, Meng, She, Zhen-Su, Zhou, Ruhong2011 · 19 citationsThe journal of physical chemistry. B. 2010;114(47):15687-93
Water dynamics clue to key residues in protein folding.20059982 · Gao, Meng, Zhu, Huaiqiu, Yao, Xin-Qiu et al.2010 · 10 citationsBiochemical and biophysical research communications. 2010;392(1):95-9
Career total: 67 works. 35 are in this corpus.
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