YP
Yijun Pan
Alzheimer DiseaseAlzheimer’s diseaseblood-brain barrierAlzheimer's diseaseP-glycoproteinCognitive Dysfunctiondocosahexaenoic acidMicrogliadementiamachine learning
On Valency
published · living versionsW_zbunfz7y·v1 · currentpublished
Occamy-1.0: Open Pareto-frontier 35B Intelligence for Co-work
with Wenhui Chen, Shiwen Cheng, Hao Dong, Chenda Duan +38
1 version
Preprints & journals
80 papers in the corpus · 2001–2026Occamy-1.0: Open Pareto-frontier 35B Intelligence for Co-work2609.11977v1 · Wenhui Chen, Shiwen Cheng, Hao Dong et al.2026 · 0 citationsarXivon Valency
Cardiometabolic medication exposures and cognitive outcomes in Alzheimer's disease.42735389 · Wang, Yihan, Goudey, Benjamin, Masters, Colin L et al.2026 · 0 citationsAge and ageing. 2026;55(9)
Mechanism Exploration of Astaxanthin in the Treatment of Adriamycin-induced Cardiotoxicity based on Network Pharmacology and Experimental Validation.39473251 · Zhu, Yu, Chen, Mengyao, Xie, Lin et al.2026 · 1 citationCurrent medicinal chemistry. 2026;33(1):159-173
Development and validation of an interpretable clinical scoring model to monitor the progression of preclinical Alzheimer's disease.41413577 · Chu, Chenyin, Wang, Yihan, Ma, Liwei et al.2026 · 0 citationsAlzheimer's research & therapy. 2025;17(1):268
Predicting severity of cerebral amyloid angiopathy neuropathology: A modeling approach using NACC and ROSMAP data.41057989 · Chu, Chenyin, Ma, Liwei, Wang, Yihan et al.2026 · 4 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(10):e70057
Proteomic analysis of brain and spinal cord tissue reveals distinct immune and mitochondrial processes between human and mouse ALS models.41028049 · Spiteri, Alanna G, Steele, Joel R, Lee, Han-Chung et al.2025 · 3 citationsScientific reports. 2025;15(1):33959
Multidimensional analysis of cerebral iron and vascular changes in chronic unilateral middle cerebral artery stenosis with quantitative susceptibility mapping, arterial spin labeling and high-resolution vessel wall imaging-a pilot study.41081149 · Zhang, Ranying, Lv, Peng, Wu, Puye et al.2025 · 0 citationsQuantitative imaging in medicine and surgery. 2025;15(10):8968-8980
Increased ATP production and P-glycoprotein activity underlie the marked changes in blood-brain barrier transport of drugs in a mouse model of amyotrophic lateral sclerosis.40891024 · Pan, Yijun, Spiteri, Alanna G, Runwal, Pranav et al.2025 · 3 citationsBritish journal of pharmacology. 2026;183(2):280-295
Development and validation of a predictive model to forecast the cerebrovascular risk burden in older people using the NACC and ROSMAP dataset.40791103 · Chu, Chenyin, Wang, Yihan, Ma, Liwei et al.2025 · 3 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(8):e70543
Prognostic value of miR-106a and miR-20a in AML patients with chemotherapy or allo-HSCT treatment.40699038 · Liu, Yue, Liu, Jiayu, Feng, Yuehua et al.2025 · 1 citationHematology (Amsterdam, Netherlands). 2025;30(1):2533577
DATE-LM: Benchmarking Data Attribution Evaluation for Large Language Models2507.09424v2 · Cathy Jiao, Yijun Pan, Emily Xiao et al.2025 · 0 citationsarXiv
Development and validation of a model to predict the progression of Alzheimer's disease.40705053 · Chu, Chenyin, Wang, Yihan, L H Huynh, Andrew et al.2025 · 1 citationAge and ageing. 2025;54(7)
Be.FM: Open Foundation Models for Human Behavior2505.23058v1 · Yutong Xie, Zhuoheng Li, Xiyuan Wang et al.2025 · 0 citationsarXiv
Evaluation of the Anti-Inflammatory Effects of Novel Fatty Acid-Binding Protein 4 Inhibitors in Microglia.40234265 · Low, Yi Ling, Kreutzer, Ethan, Chandrashekaran, Indu R et al.2025 · 3 citationsJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2025;20(1):40
Developing and validating a prediction tool for cerebral amyloid angiopathy neuropathological severity.40042448 · Chu, Chenyin, Wang, Yihan, Ma, Liwei et al.2025 · 7 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(3):e14583
Exploring epidemiological risk factors for cerebral amyloid angiopathy: Considerations for monoclonal antibody therapy in people with Alzheimer's disease.40042470 · Ma, Liwei, Wang, Yihan, Huynh, Andrew Liem Hieu et al.2025 · 8 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(3):e14602
Detecting and Filtering Unsafe Training Data via Data Attribution with Denoised Representation2502.11411v2 · Yijun Pan, Taiwei Shi, Jieyu Zhao et al.2025 · 0 citationsarXiv
Unraveling the bidirectional link between cancer and dementia and the impact of cancer therapies on dementia risk: A systematic review and meta-analysis.39807644 · Ma, Liwei, Tan, Edwin C K, Goudey, Benjamin et al.2025 · 19 citationsAlzheimer's & dementia : the journal of the Alzheimer's Association. 2025;21(2):e14540
Development and Validation of a Tool to Predict Onset of Mild Cognitive Impairment and Alzheimer Dementia.39775804 · Chu, Chenyin, Wang, Yifei, Wang, Yihan et al.2025 · 10 citationsJAMA network open. 2025;8(1):e2453756
A case report of PGAP2-related hyperphosphatasia with impaired intellectual development syndrome in a Chinese family and literature review.39687712 · Pan, Yijun, Ren, Bin, Chen, Lijuan et al.2025 · 2 citationsFrontiers in pediatrics. 2024;12:1419976
Bridging AI and Science: Implications from a Large-Scale Literature Analysis of AI4Science2412.09628v2 · Yutong Xie, Yijun Pan, Hua Xu et al.2024 · 6 citationsarXiv
Reporting practices of anesthetic and analgesic use in rodent orthopedic research.39557905 · Pan, Yijun, Cohen, Shari2024 · 2 citationsScientific reports. 2024;14(1):26225
: A Library for Efficient Data Attribution2410.04555v1 · Junwei Deng, Ting-Wei Li, Shiyuan Zhang et al.2024 · 0 citationsarXiv
Development and validation of the Florey Dementia Risk Score web-based tool to screen for Alzheimer's disease in primary care.39328810 · Pan, Yijun, Chu, Chenyin, Wang, Yifei et al.2025 · 10 citationsEClinicalMedicine. 2024;76:102834
Clearance and transport of amyloid β by peripheral monocytes correlate with Alzheimer's disease progression.39266542 · Huang, Xin, Fowler, Chris, Li, Yihan et al.2024 · 36 citationsNature communications. 2024;15(1):7998
Exploring the molecular mechanism of ginseng against anthracycline-induced cardiotoxicity based on network pharmacology, molecular docking and molecular dynamics simulation.39243097 · Xie, Lin, Liu, Hanze, Zhang, Ke et al.2024 · 4 citationsHereditas. 2024;161(1):31
Understanding machine learning applications in dementia research and clinical practice: a review for biomedical scientists and clinicians.39085973 · Wang, Yihan, Liu, Shu, Spiteri, Alanna G et al.2024 · 44 citationsAlzheimer's research & therapy. 2024;16(1):175
Iron Reduces the Trafficking of Fatty Acids from Human Immortalised Brain Microvascular Endothelial Cells Through Modulation of Fatty Acid Transport Protein 1 (FATP1/SLC27A1).39044044 · Supti, Showmika T, Koehn, Liam M, Newman, Stephanie A et al.2024 · 7 citationsPharmaceutical research. 2024;41(8):1631-1648
A need to integrate pharmacological management for multimorbidity into dementia guidelines in Australia.39109156 · Nagar, Sanket, Ma, Liwei, Pan, Yijun et al.2024 · 1 citationFrontiers in public health. 2024;12:1425195
Elucidating the Link Between Anxiety/Depression and Alzheimer's Dementia in the Australian Imaging Biomarkers and Lifestyle (AIBL) Study.38896210 · Ma, Liwei, Tan, Edwin C K, Bush, Ashley I et al.2024 · 13 citationsJournal of epidemiology and global health. 2024;14(3):1130-1141
Exploring the link between comorbidities and Alzheimer's dementia in the Australian Imaging, Biomarker & Lifestyle (AIBL) study.38770381 · Nguyen, Catherine Quynh Nhu, Ma, Liwei, Low, Yi Ling Clare et al.2025 · 3 citationsAlzheimer's & dementia (Amsterdam, Netherlands). 2024;16(2):e12593
Exploring the association between cancer and cognitive impairment in the Australian Imaging Biomarkers and Lifestyle (AIBL) study.38388558 · Ma, Liwei, Low, Yi Ling Clare, Zhuo, Yuanhao et al.2024 · 2 citationsScientific reports. 2024;14(1):4364
Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth.38388563 · Suda, Akane, Umaru, Banlanjo Abdulaziz, Yamamoto, Yui et al.2024 · 39 citationsScientific reports. 2024;14(1):4409
How Can We Use Mathematical Modeling of Amyloid-β in Alzheimer's Disease Research and Clinical Practices?38007665 · Chu, Chenyin, Low, Yi Ling Clare, Ma, Liwei et al.2024 · 7 citationsJournal of Alzheimer's disease : JAD. 2024;97(1):89-100
Network Pharmacology along with Molecular Docking to Explore the Mechanism of Danshen Injection against Anthracycline-induced Cardiotoxicity and Transcriptome Validation.38482629 · Dai, Quankai, Pan, Yijun, Zhu, Xiwen et al.2024 · 5 citationsCurrent pharmaceutical design. 2024;30(12):952-967
A Comparison of an Australian Observational Longitudinal Alzheimer's Disease Cohort to Community-Based Australian Data.39213065 · Huynh, Andrew Liem Hieu, Wang, Yihan, Ma, Liwei et al.2024 · 3 citationsJournal of Alzheimer's disease : JAD. 2024;101(3):737-749
Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide.37555918 · Kagawa, Yoshiteru, Low, Yi Ling, Pyun, Jae et al.2023 · 23 citationsJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023;18(3):448-461
Cu(ATSM) Increases P-Glycoprotein Expression and Function at the Blood-Brain Barrier in C57BL6/J Mice.37631298 · Pyun, Jae, Koay, HuiJing, Runwal, Pranav et al.2024 · 16 citationsPharmaceutics. 2023;15(8)
Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice.37226029 · Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi et al.2023 · 12 citationsNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023;20(4):1198-1214
Altered Blood-Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis.36559296 · Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi et al.2022 · 18 citationsPharmaceutics. 2022;14(12)
Oleic acid-bound FABP7 drives glioma cell proliferation through regulation of nuclear lipid droplet formation.36325660 · Umaru, Banlanjo Abdulaziz, Kagawa, Yoshiteru, Ohsaki, Yuki et al.2023 · 27 citationsThe FEBS journal. 2023;290(7):1798-1821
A Fluorescent Peptide Toxin for Selective Visualization of the Voltage-Gated Potassium Channel KV1.3.36330854 · Wai, Dorothy C C, Naseem, Muhammad Umair, Mocsár, Gábor et al.2022 · 7 citationsBioconjugate chemistry. 2022;33(11):2197-2212
Altered peripheral factors affecting the absorption, distribution, metabolism, and excretion of oral medicines in Alzheimer's disease.35421522 · Waller, Elka S, Yardeny, Ben J, Fong, Wan Yun et al.2022 · 12 citationsAdvanced drug delivery reviews. 2022;185:114282
Altered blood-brain barrier and blood-spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety.35048358 · Pan, Yijun, Nicolazzo, Joseph A2022 · 53 citationsBritish journal of pharmacology. 2022;179(11):2577-2588
Blockade of Microglial Kv1.3 Potassium Channels by the Peptide HsTX1[R14A] Attenuates Lipopolysaccharide-mediated Neuroinflammation.34767826 · Nicolazzo, Joseph A, Pan, Yijun, Di Stefano, Ilenia et al.2022 · 19 citationsJournal of pharmaceutical sciences. 2022;111(3):638-647
Correction to Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer's Disease.34478315 · Pan, Yijun, Omori, Kotaro, Ali, Izna et al.2021 · 1 citationMolecular pharmaceutics. 2021;18(10):3928-3929
Unraveling synonymous and deep intronic variants causing aberrant splicing in two genetically undiagnosed epilepsy families.34107977 · Li, Qiang, Wang, Yiting, Pan, Yijun et al.2024 · 12 citationsBMC medical genomics. 2021;14(1):152
Profiling the expression of fatty acid-binding proteins and fatty acid transporters in mouse microglia and assessing their role in docosahexaenoic acid-d5 uptake.34098488 · Low, Y L, Pan, Y, Short, J L et al.2022 · 14 citationsProstaglandins, leukotrienes, and essential fatty acids. 2021;171:102303
Ligand Bound Fatty Acid Binding Protein 7 (FABP7) Drives Melanoma Cell Proliferation Via Modulation of Wnt/β-Catenin Signaling.33646504 · Umaru, Banlanjo Abdulaziz, Kagawa, Yoshiteru, Shil, Subrata Kumar et al.2021 · 23 citationsPharmaceutical research. 2021;38(3):479-490
Endosomal escape cell-penetrating peptides significantly enhance pharmacological effectiveness and CNS activity of systemically administered antisense oligonucleotides.33640427 · Dastpeyman, Mohadeseh, Sharifi, Ramin, Amin, Azin et al.2021 · 27 citationsInternational journal of pharmaceutics. 2021;599:120398
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