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TG

Thomas Gregor

q-bio.MNphysics.bio-phGene Expression Regulation, DevelopmentalDrosophilaTranscription, Geneticdevelopmental biologyBody PatterningDrosophila ProteinsModels, Biologicalq-bio.CB

On Valency

published · living versions
W_c942f7vc·v1 · currentpublished
The role of input noise in transcriptional regulation
with Gasper Tkacik, William Bialek
1 version
W_3brsv4aa·v1published

Preprints & journals

76 papers in the corpus · 2005–2026
Designing sustainability under Earth-system rate constraints2610.34026v1 · Jos'e Halloy, Petros Chatzimpiros, Francois Graner et al.2026 · 0 citationsarXiv
Invariant nonequilibrium dynamics in gene regulation optimize information flow.42406962 · Zoller, Benjamin, Bénichou, Alexis, Gregor, Thomas et al.2026 · 0 citationsProceedings of the National Academy of Sciences of the United States of America. 2026;123(28):e2524855123
FISH-Dist: An Automated Pipeline for 3D Genomic Spatial Distance Quantification in FISH Imaging.41899799 · Aigouy, Benoit, Caturegli, Emmanuelle, Charroux, Bernard et al.2026 · 0 citationsBioengineering (Basel, Switzerland). 2026;13(3)
Loop Extrusion Accelerates Long-Range Enhancer-Promoter Searches in Living Embryos.41756876 · Choppakatla, Pavan, Patel, Aleena L, Borjigin, Tohn et al.2026 · 4 citationsbioRxiv : the preprint server for biology. 2026
The Physics of Sustainability: Material and Power Constraints for the Long Term2512.10680v1 · Jos'e Halloy, Petros Chatzimpiros, Francois Graner et al.2025 · 1 citationarXiv
Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids.41020403 · Pineau, Judith, Wong-Ng, Jerome, Mayran, Alexandre et al.2025 · 6 citationsDevelopment (Cambridge, England). 2025;152(18)
Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos.40845108 · Bennabi, Isma, Hansen, Pauline, Merle, Melody et al.2025 · 10 citationsScience advances. 2025;11(34):eadv7790
Invariant non-equilibrium dynamics of transcriptional regulation optimize information flow.40709307 · Zoller, Benjamin, Bénichou, Alexis, Gregor, Thomas et al.2026 · 0 citationsArXiv. 2025
Bridging spatial and temporal scales of developmental gene regulation.39975433 · Cardona, Andrés H, Peixoto, Márcia Mesquita, Borjigin, Tohn et al.2025 · 5 citationsArXiv. 2025
Deriving a genetic regulatory network from an optimization principle.39752518 · Sokolowski, Thomas R, Gregor, Thomas, Bialek, William et al.2025 · 24 citationsProceedings of the National Academy of Sciences of the United States of America. 2025;122(1):e2402925121
Gene activity fully predicts transcriptional bursting dynamics.37131882 · Chen, Po-Ta, Levo, Michal, Zoller, Benjamin et al.2026 · 19 citationsArXiv. 2024
Transcription factor clusters as information transfer agents.38495568 · Munshi, Rahul, Ling, Jia, Ryabichko, Sergey et al.2026 · 12 citationsArXiv. 2024
Precise and scalable self-organization in mammalian pseudo-embryos.38491138 · Merle, Mélody, Friedman, Leah, Chureau, Corinne et al.2024 · 56 citationsNature structural & molecular biology. 2024;31(6):896-902
Finding the last bits of positional information.39664616 · McGough, Lauren, Casademunt, Helena, Nikolić, Miloš et al.2026 · 19 citationsPRX life. 2024;2(1)
Scale invariance in early embryonic development.38235065 · Nikolić, Miloš, Antonetti, Victoria, Liu, Feng et al.2026 · 18 citationsArXiv. 2023
Functional analysis of the Drosophila eve locus in response to non-canonical combinations of gap gene expression levels.37890488 · Haroush, Netta, Levo, Michal, Wieschaus, Eric F et al.2023 · 5 citationsDevelopmental cell. 2023;58(23):2789-2801.e5
Functional analysis of a gene locus in response to non-canonical combinations of transcription factors2308.05685v1 · Netta Haroush, Michal Levo, Eric Wieschaus et al.2023 · 0 citationsarXiv
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.37419111 · Dekker, Job, Alber, Frank, Aufmkolk, Sarah et al.2023 · 91 citationsMolecular cell. 2023;83(15):2624-2640
Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system.36897970 · Davidescu, Mircea R, Romanczuk, Pawel, Gregor, Thomas et al.2023 · 24 citationsProceedings of the National Academy of Sciences of the United States of America. 2023;120(11):e2206163120
Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome.36711618 · Brückner, David B, Chen, Hongtao, Barinov, Lev et al.2024 · 111 citationsbioRxiv : the preprint server for biology. 2023
Structured foraging of soil predators unveils functional responses to bacterial defenses.36538486 · Rossine, Fernando W, Vercelli, Gabriel T, Tarnita, Corina E et al.2022 · 11 citationsProceedings of the National Academy of Sciences of the United States of America. 2022;119(52):e2210995119
Eukaryotic gene regulation at equilibrium, or non?36590072 · Zoller, Benjamin, Gregor, Thomas, Tkačik, Gašper2025 · 32 citationsCurrent opinion in systems biology. 2022;31
Temporally dynamic antagonism between transcription and chromatin compaction controls stochastic photoreceptor specification in flies.35835116 · Voortman, Lukas, Anderson, Caitlin, Urban, Elizabeth et al.2022 · 21 citationsDevelopmental cell. 2022;57(15):1817-1832.e5
Latent space of a small genetic network: Geometry of dynamics and information.35737842 · Seyboldt, Rabea, Lavoie, Juliette, Henry, Adrien et al.2022 · 18 citationsProceedings of the National Academy of Sciences of the United States of America. 2022;119(26):e2113651119
The Impact of Space and Time on the Functional Output of the Genome.34230036 · Nollmann, Marcelo, Bennabi, Isma, Götz, Markus et al.2022 · 20 citationsCold Spring Harbor perspectives in biology. 2022;14(4)
Transcriptional coupling of distant regulatory genes in living embryos.35508662 · Levo, Michal, Raimundo, João, Bing, Xin Yang et al.2022 · 187 citationsNature. 2022;605(7911):754-760
Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation.35320726 · Singh, Anand P, Wu, Ping, Ryabichko, Sergey et al.2022 · 44 citationsCell reports. 2022;38(12):110543
Trading bits in the readout from a genetic network.34772813 · Bauer, Marianne, Petkova, Mariela D, Gregor, Thomas et al.2021 · 35 citationsProceedings of the National Academy of Sciences of the United States of America. 2021;118(46)
Physics meets biology: The joining of two forces to further our understanding of cellular function.34358454 · Wang, Michelle D, Nicodemi, Mario, Dekker, Nynke H et al.2021 · 2 citationsMolecular cell. 2021;81(15):3033-3037
The many bits of positional information.33526425 · Tkačik, Gašper, Gregor, Thomas2021 · 77 citationsDevelopment (Cambridge, England). 2021;148(2)
Transcription-dependent spatial organization of a gene locus2012.15819v1 · Lev Barinov, Sergey Ryabichko, William Bialek et al.2020 · 9 citationsarXiv
Eco-evolutionary significance of "loners".32191693 · Rossine, Fernando W, Martinez-Garcia, Ricardo, Sgro, Allyson E et al.2020 · 30 citationsPLoS biology. 2020;18(3):e3000642
Using RNA Tags for Multicolor Live Imaging of Chromatin Loci and Transcription in Drosophila Embryos.32710421 · Chen, Hongtao, Gregor, Thomas2021 · 3 citationsMethods in molecular biology (Clifton, N.J.). 2020;2166:373-384
Action at a distance in transcriptional regulation1912.08579v1 · William Bialek, Thomas Gregor, Gasper Tkacik2019 · 12 citationsarXiv
Optimal Decoding of Cellular Identities in a Genetic Network.30712870 · Petkova, Mariela D, Tkačik, Gašper, Bialek, William et al.2019 · 186 citationsCell. 2019;176(4):844-855.e15
Precise spatial scaling in the early fly embryo1812.11384v1 · Victoria Antonetti, William Bialek, Thomas Gregor et al.2018 · 1 citationarXiv
Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting.30340044 · Zoller, Benjamin, Little, Shawn C, Gregor, Thomas2019 · 140 citationsCell. 2018;175(3):835-847.e25
Dynamic interplay between enhancer-promoter topology and gene activity.30038397 · Chen, Hongtao, Levo, Michal, Barinov, Lev et al.2019 · 482 citationsNature genetics. 2018;50(9):1296-1303
Single mRNA Molecule Detection in Drosophila.29130194 · Little, Shawn C, Gregor, Thomas2018 · 37 citationsMethods in molecular biology (Clifton, N.J.). 2018;1649:127-142
Live Imaging of mRNA Synthesis in Drosophila.29130209 · Garcia, Hernan G, Gregor, Thomas2018 · 20 citationsMethods in molecular biology (Clifton, N.J.). 2018;1649:349-357
Diverse spatial expression patterns emerge from common transcription bursting kinetics1712.08215v1 · Benjamin Zoller, Shawn C. Little, Thomas Gregor2017 · 3 citationsarXiv
Beyond D'Arcy Thompson: Future challenges for quantitative biology.28341396 · Gregor, Thomas2018 · 2 citationsMechanisms of development. 2017;145:10-12
Direct visualization of transcriptional activation by physical enhancer-promoter proximity10.1101/099523v2 · Chen, H., Fujioka, M., Jaynes, J. B. et al.2017 · 9 citationsbioRxiv
Only accessible information is useful: insights from gradient-mediated patterning.26716005 · Tikhonov, Mikhail, Little, Shawn C, Gregor, Thomas2015 · 15 citationsRoyal Society open science. 2015;2(11):150486
Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo.26267217 · Bothma, Jacques P, Garcia, Hernan G, Ng, Samuel et al.2016 · 193 citationseLife. 2015;4
Modeling oscillations and spiral waves in Dictyostelium populations.26172740 · Noorbakhsh, Javad, Schwab, David J, Sgro, Allyson E et al.2016 · 46 citationsPhysical review. E, Statistical, nonlinear, and soft matter physics. 2015;91(6):062711
Career total: at least 150 works. 76 are in this corpus.Showing the 50 most recent.

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