NH

Nir Hacohen

0000-0002-2349-2656

immunologyMelanomaCOVID-19ImmunotherapygenomicsCD8-Positive T-LymphocytesNeoplasmscancer biologyimmunotherapySARS-CoV-2

On Valency

published · living versions

MoLRSI: A Recursive Self-Improving AI agent for Molecular Discovery

with Yikun Zhang, Xiwei Cheng, Mingze Yuan, Yu Zhang +13

1 version

W_ka3rjr2vv1 · current

Preprints & journals

316 papers in the corpus · 1989–2026

Personalized neoantigen-targeting cancer vaccines in ovarian cancer: a phase 1 trial.

Sellars, MacLean C, Frank, Jessica A, Shim, Bohoon et al.

0 citations

428755582026Nature medicine. 2026

Launching an independent research laboratory and scientific career: Tools for a rapidly changing landscape.

Roy, Simon F, Fan, Amy C, Bennion, Kelsey B et al.

0 citations

428621062026The Journal of experimental medicine. 2026;223(11)

One-carbon metabolism sustains effector T cell function through cell-surface glycosylation.

Wang, Peng, Yu, Amy, Mutaher, Mohammed et al.

0 citations

429266742026bioRxiv : the preprint server for biology. 2026

RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation.

De Silva, Pushpamali, Fitzgerald, Samantha, Cazaubiel, Jules et al.

0 citations

427770432026Science advances. 2026;12(39):eadz6907

Rethinking the Benign Nature of Class II Lupus Nephritis.

Shwetar, Jasmine J, Fava, Andrea, Keegan, Sarah et al.

0 citations

427798772026bioRxiv : the preprint server for biology. 2026

Author Correction: Specific oncogene activation of the cell of origin in mucosal melanoma.

Babu, Swathy, Chen, Jiajia, Baron, Chloé S et al.

0 citations

426248472026Nature communications. 2026;17(1)

A population-scale transcriptional atlas of blood and tissue in lupus nephritis.

Sugiarto, Nicholas W, Gurajala, Siddarth, Curtis, Michelle et al.

0 citations

426168392026Science translational medicine. 2026;18(863):eaec0512

UV irradiation drives lineage-specific MITF-mediated transcription of PD-L1 to confer immune tolerance to UV-mutated melanocytes.

Lo, Jennifer A, Rachmin, Inbal, Flesher, Jessica L et al.

1 citation

425948732026Immunity. 2026;59(9):2500-2514.e8

Immune and stromal features of durable complete response to radiation and dual immune checkpoint blockade in pancreatic cancer.

Kang, Sarah, Parikh, Milan, Pappas, Leontios et al.

0 citations

428456332026medRxiv : the preprint server for health sciences. 2026

CRTC, not phosphorylated CREB1, drives cAMP-induced transcription across diverse cell types.

Adelmann, Charles H, Liu, Michelle, Greuel, Allison E et al.

0 citations

426196772026bioRxiv : the preprint server for biology. 2026

Single-nucleus multimodal spatial transcriptomics reveals spatial colocalization of neoantigen-expressing tumor cells and cognate T cells.

Nagler, Adi, Sud, Amit, Ghannam, Jack Y et al.

1 citation

424869692026Nature biotechnology. 2026

Multimodal blood based proteomic profiling reveals insights into mechanisms of immunotherapy resistance.

Wright, Samuel J, Zamora, Izabella, Parikh, Milan et al.

0 citations

423427042026Nature communications. 2026;17(1)

Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors.

Schwartz, Marc A, Lue, Dillon, Mutaher, Mohammed et al.

0 citations

423679352026bioRxiv : the preprint server for biology. 2026

Attack of the clones: Tracing the dynamics of innate immune cells in human cancer.

Brivanlou, Amir, Hacohen, Nir

0 citations

422760482026Cancer cell. 2026;44(7):1327-1329

Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function alterations.

Tsingas, Konstantinos, Thomas, Monzy, Reale, McKenna et al.

0 citations

422345612026Cell reports. 2026;45(6):117455

A community machine learning challenge to predict the effects of gene perturbations on T cell differentiation for cancer immunotherapy.

Zhang, Jiaqi, Schwartz, Marc A, Mutaher, Mohammed et al.

0 citations

422390452026bioRxiv : the preprint server for biology. 2026

Spatially Distinct Macrophage Subsets Drive Myofibroblast Heterogeneity and Maladaptive Fibrosis in Lupus Nephritis.

Raparia, Chirag, Hoover, Paul, Ai, Junting et al.

1 citation

420945782026bioRxiv : the preprint server for biology. 2026

Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression.

Hoover, Paul J, Eisenhaure, Thomas M, Hodgin, Jeffrey et al.

2 citations

420559192026Annals of the rheumatic diseases. 2026;85(7):1324-1340

An affinity reagent-conjugated biotin ligase for amplified cell surface labelling in vitro and in vivo.

Holden, Beck, Mutaher, Mohammed, Raychowdhury, Raktima et al.

0 citations

419517762026Scientific reports. 2026;16(1)

A population-scale atlas of blood and tissue in lupus nephritis.

Sugiarto, Nicholas W, Gurajala, Siddarth, Curtis, Michelle et al.

4 citations

419592442026bioRxiv : the preprint server for biology. 2026

Sensitive detection of cancer antigens enabled by user-defined peptide libraries.

Manakongtreecheep, Kasidet, Ctortecka, Claudia, Correa-Medero, Luis O et al.

2 citations

416635422026Nature biotechnology. 2026

Training Tomorrow's Leaders in Cancer Immunology.

Tan, Yuqi, Kim, B J, Mujal, Adriana M et al.

1 citation

415242762026Cancer immunology research. 2026;14(2):186-193

CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer.

Chen, Alex C Y, Ji, Keely Y, Yerinde, Cansu et al.

1 citation

416022802026bioRxiv : the preprint server for biology. 2026

Proteotranscriptomic Dissection of Breast Cancer T Cell States Identifies CD103+ Tfh-derived Cytotoxic Cells Linked to Immunotherapy Response.

Al-Eryani, Ghamdan, Van Der Leij, Sophie, Masle-Farquhar, Etienne et al.

1 citation

415420422026Research square. 2026

Accelerating Scientific Discovery with Autonomous Goal-evolving Agents

Yuanqi Du, Botao Yu, Tianyu Liu et al.

1 citation

2512.21782v22025arXiv

UV induces common cutaneous amyloid-like melanosomal protein aggregates.

Theodosakis, Nicholas, Howland, Porter B, Hejna, Miroslav et al.

0 citations

414461982025bioRxiv : the preprint server for biology. 2025

Letter to the EditorTumor-infiltrating lymphocyte therapy generated from melanoma brain metastasis: Proof-of-concept for CNS-derived cellular immunotherapy.

Grewal, Eric P, Steuart, Samuel J, Liu, Baolin et al.

0 citations

413979192026Neuro-oncology. 2026;28(3):815-818

Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics.

Avraham-Davidi, Inbal, Mages, Simon, Klughammer, Johanna et al.

3 citations

413844922025eLife. 2025;14

Lymphotoxin-driven cancer cell eradication by tumoricidal CD8+ TIL.

Xie, Hongyan, Jiang, Aiping, Dey, Aonkon et al.

0 citations

413327502025bioRxiv : the preprint server for biology. 2025

Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy.

Knight, Andrew D, Robitschek, Emily J, Lin, Jia-Ren et al.

0 citations

412828202026medRxiv : the preprint server for health sciences. 2025

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity.

Slowikowski, Kamil, Sen, Pritha, Cosgriff, Christopher V et al.

3 citations

413328372025medRxiv : the preprint server for health sciences. 2025

RNA splicing dynamics in CD8 T cells uncovers isoforms that impact T cell-mediated cancer immunotherapy

Tzaban, S., appasamy, p., Zisman, E. et al.

0 citations

10.1101/2025.09.07.674706v12025bioRxiv

A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis.

Hoover, Paul J, Raparia, Chirag, Lieb, David J et al.

21 citations

409001242025The Journal of experimental medicine. 2025;222(11)

Differential T cell clonal dynamics underlie outcomes to frontline chemoimmunotherapy in advanced gastric cancer.

Wright, Samuel J, Kang, Sarah, An, Minae et al.

1 citation

409098282026medRxiv : the preprint server for health sciences. 2025

Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanoma.

Tiago, Manoela, Purwin, Timothy J, Stefanski, Casey D et al.

6 citations

409556632025The Journal of clinical investigation. 2025;135(18)

Single-cell image-based screens identify host regulators of Ebola virus infection dynamics.

Carlson, Rebecca J, Patten, J J, Stefanakis, George et al.

13 citations

407078322025Nature microbiology. 2025;10(8):1989-2002

Facts and Hopes: Toward the Next Quantum Leap in Melanoma.

Flaherty, Keith T, Aplin, Andrew E, Davies, Michael A et al.

7 citations

404077222025Clinical cancer research : an official journal of the American Association for Cancer Research. 2025;31(14):2882-2889

A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma.

Blass, Eryn, Keskin, Derin B, Tu, Chloe R et al.

42 citations

406451792025Cell. 2025;188(19):5125-5141.e27

Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants.

Revach, Or-Yam, Cicerchia, Angelina M, Shorer, Ofir et al.

12 citations

405783642025Cell reports. Medicine. 2025;6(7):102210

Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics.

Avraham-Davidi, Inbal, Mages, Simon, Klughammer, Johanna et al.

22 citations

406672582025bioRxiv : the preprint server for biology. 2025

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis.

Horisberger, Alice, Griffith, Alec, Keegan, Joshua et al.

18 citations

405368132025The Journal of clinical investigation. 2025;135(16)

The Society for Immunotherapy of Cancer Perspective on Liquid Biopsy- and Radiomics-Based Technologies for Immuno-oncology Biomarker Discovery and Application.

Monette, Anne, Aguilar-Mahecha, Adriana, Altinmakas, Emre et al.

5 citations

401976262025Clinical cancer research : an official journal of the American Association for Cancer Research. 2025;31(12):2278-2293

Longitudinal Immune Profiling in Sepsis Reveals Transient Expansion of a CD14+ Monocyte State and Persistent T Cell Suppression

Ankomah, P. O., DuBois, A., Sonny, A. et al.

0 citations

10.1101/2025.05.17.25327533v12025medRxiv

CREB5 promotes immunotherapy resistance via tumor-intrinsic collagenmatrix deposition

Tiwari, P., Colvin, K. J., Kim, S. Y. et al.

1 citation

10.1101/2025.04.22.649109v12025bioRxiv

Multimodal blood based profiling reveals insights into mechanisms of immunotherapy resistance

Wright, S. J., Zamora, I., Parikh, M. et al.

0 citations

10.1101/2025.04.20.25325955v12025medRxiv

Unveiling alternative splicing dynamics in activated T lymphocytes and their implications for immune checkpoint blockade efficacy.

Zisman, Elad, Stern, Ori, Lewis, Reyut et al.

3 citations

404691042025iScience. 2025;28(5):112434

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.

Inamo, Jun, Keegan, Joshua, Griffith, Alec et al.

37 citations

400918332025The Journal of clinical investigation. 2025;135(6)

Batch correcting single-cell spatial transcriptomics count data with Crescendo improves visualization and detection of spatial gene patterns.

Millard, Nghia, Chen, Jonathan H, Palshikar, Mukta G et al.

13 citations

400010842025Genome biology. 2025;26(1):36

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma.

Braun, David A, Moranzoni, Giorgia, Chea, Vipheaviny et al.

209 citations

399103012025Nature. 2025;639(8054):474-482

The Society for Immunotherapy of Cancer Perspective on Tissue-Based Technologies for Immuno-Oncology Biomarker Discovery and Application.

Monette, Anne, Aguilar-Mahecha, Adriana, Altinmakas, Emre et al.

14 citations

396258182025Clinical cancer research : an official journal of the American Association for Cancer Research. 2025;31(3):439-456

Career total: 624 works. 316 are in this corpus.Showing the 50 most recent.

Profile built from the corpus for this byline.

624

works

103K

citations

125

h-index

Corpus papers per year

Corpus papers per year, 1989 to 2026. Busiest year 2021, 32 papers.
Year	Papers
1989	2
1990	0
1991	0
1992	0
1993	0
1994	0
1995	0
1996	3
1997	0
1998	1
1999	2
2000	0
2001	1
2002	2
2003	0
2004	1
2005	0
2006	4
2007	0
2008	3
2009	8
2010	6
2011	12
2012	6
2013	8
2014	19
2015	10
2016	8
2017	14
2018	18
2019	18
2020	31
2021	32
2022	13
2023	26
2024	19
2025	25
2026	24

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