OR
Oliver Rausch
cancer biologyDrug DesignMethyltransferasesMitogen-Activated Protein KinasesZinc FingersAdaptor Proteins, Signal TransducingAdaptor Proteins, Vesicular TransportAdenosineAlternative Splicingbioinformatics
On Valency
published · living versionsW_63ueycek·v1 · currentpublished
Discovering Language Model Behaviors with Model-Written Evaluations
with Ethan Perez, Sam Ringer, Kamilė Lukošiūtė, Karina Nguyen +58
1 version
Preprints & journals
34 papers in the corpus · 1995–2025Inhibition of METTL3 by STC-15 induces RNA misprocessing that results in dsRNA formation and activates innate immunity10.64898/2025.12.05.692335v1 · Fischl, H., Samuels, T. J., Andrews, B. et al.2025 · 4 citationsbioRxiv
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation.40435410 · Mayday, Madeline Y, Biancon, Giulia, Wei, Manyi et al.2025 · 13 citationsBlood. 2025;146(9):1096-1109
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and WNT pathway activation10.1101/2025.02.19.638991v1 · Mayday, M. Y., Biancon, G., Wei, M. et al.2025 · 14 citationsbioRxiv
Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.37464070 · Sturgess, Katherine, Yankova, Eliza, Vijayabaskar, M S et al.2023 · 32 citationsLeukemia. 2023;37(10):2133-2137
Author Correction: RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals.37415011 · Rücklé, Cornelia, Körtel, Nadine, Basilicata, M Felicia et al.2023 · 2 citationsNature structural & molecular biology. 2023;30(10):1607
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.37548590 · Guirguis, Andrew A, Ofir-Rosenfeld, Yaara, Knezevic, Kathy et al.2023 · 129 citationsCancer discovery. 2023;13(10):2228-2247
RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals.37202476 · Rücklé, Cornelia, Körtel, Nadine, Basilicata, M Felicia et al.2023 · 39 citationsNature structural & molecular biology. 2023;30(8):1207-1215
Discovering Language Model Behaviors with Model-Written Evaluations2212.09251v1 · Ethan Perez, Sam Ringer, Kamil\.e Lukosi\=ut\.e et al.2022 · 224 citationsarXivon Valency
Predicting genes associated with RNA methylation pathways using machine learning.36008532 · Tsagkogeorga, Georgia, Santos-Rosa, Helena, Alendar, Andrej et al.2022 · 11 citationsCommunications biology. 2022;5(1):868
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.33902106 · Yankova, Eliza, Blackaby, Wesley, Albertella, Mark et al.2022 · 1,416 citationsNature. 2021;593(7860):597-601
Predicting genes associated with RNA methylation pathways using machine learning10.1101/2021.12.10.472055v1 · Tsagkogeorga, G., Santos Rosa, H., Alendar, A. et al.2021 · 11 citationsbioRxiv
Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning10.1101/2020.12.20.423675v2 · Koertel, N., Rueckle, C., Zhou, Y. et al.2020 · 142 citationsbioRxiv
RNA-modifying enzymes and their function in a chromatin context.31582848 · Tzelepis, Konstantinos, Rausch, Oliver, Kouzarides, Tony2020 · 34 citationsNature structural & molecular biology. 2019;26(10):858-862
Localizing the lipid products of PI3Kγ in neutrophils.26596865 · Norton, Laura, Lindsay, Yvonne, Deladeriere, Arnaud et al.2017 · 13 citationsAdvances in biological regulation. 2016;60:36-45
CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.27563401 · Cansfield, Andrew D, Ladduwahetty, Tammy, Sunose, Mihiro et al.2016 · 15 citationsACS medicinal chemistry letters. 2016;7(8):768-73
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.22544264 · Bergamini, Giovanna, Bell, Kathryn, Shimamura, Satoko et al.2012 · 149 citationsNature chemical biology. 2012;8(6):576-82
Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase.20861461 · Chessa, Tamara A M, Anderson, Karen E, Hu, Yanhua et al.2011 · 52 citationsBlood. 2010;116(26):6027-36
PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils.20813901 · Anderson, Karen E, Chessa, Tamara A M, Davidson, Keith et al.2011 · 67 citationsBlood. 2010;116(23):4978-89
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.18755982 · Anderson, Karen E, Boyle, Keith B, Davidson, Keith et al.2009 · 93 citationsBlood. 2008;112(13):5202-11
IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.18501603 · Buckley, George M, Fosbeary, Richard, Fraser, Joanne L et al.2008 · 51 citationsBioorganic & medicinal chemistry letters. 2008;18(12):3656-60
IRAK-4 inhibitors. Part 1: a series of amides.18474425 · Buckley, George M, Gowers, Lewis, Higueruelo, Alicia Perez et al.2008 · 38 citationsBioorganic & medicinal chemistry letters. 2008;18(11):3211-4
IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding.18482836 · Buckley, George M, Ceska, Thomas A, Fraser, Joanne L et al.2008 · 53 citationsBioorganic & medicinal chemistry letters. 2008;18(11):3291-5
High content cellular screening.16793326 · Rausch, Oliver2006 · 70 citationsCurrent opinion in chemical biology. 2006;10(4):316-20
High-Content Analysis 2005--CHI's Second Annual Conference. 25-28 January 2005, San Francisco, CA, USA.15772886 · Rausch, Oliver2006 · 0 citationsIDrugs : the investigational drugs journal. 2005;8(3):197-9
Use of high-content analysis for compound screening and target selection.15973566 · Rausch, Oliver2006 · 10 citationsIDrugs : the investigational drugs journal. 2005;8(7):573-7
Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.14557262 · Kendrick, Tulene S, Lipscombe, Richard J, Rausch, Oliver et al.2004 · 19 citationsThe Journal of biological chemistry. 2004;279(1):326-40
Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons.12691736 · Vinson, Mary, Rausch, Oliver, Maycox, Peter R et al.2003 · 87 citationsMolecular and cellular neurosciences. 2003;22(3):344-52
Nerve injury-associated kinase: a sterile 20-like protein kinase up-regulated in dorsal root ganglia in a rat model of neuropathic pain.11113325 · Rausch, O, Newton, R A, Bingham, S et al.2001 · 6 citationsNeuroscience. 2000;101(3):767-77
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.11033082 · Coghlan, M P, Culbert, A A, Cross, D A et al.2001 · 902 citationsChemistry & biology. 2000;7(10):793-803
Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation.9933603 · Rausch, O, Marshall, C J1999 · 108 citationsThe Journal of biological chemistry. 1999;274(7):4096-105
Transcription regulation and alternative splicing of an early zygotic gene encoding two structurally distinct zinc finger proteins in Xenopus laevis.9178260 · Bellefroid, E, Bourguignon, C, Bouwmeester, T et al.1997 · 7 citationsMechanisms of development. 1997;63(1):99-108
Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway.9032244 · Rausch, O, Marshall, C J1997 · 84 citationsMolecular and cellular biology. 1997;17(3):1170-9
Sequence-specific recognition of a repetitive DNA element by a C2H2 zinc-finger protein in Xenopus.8001572 · Schäfer, U, Rausch, O, Bouwmeester, T et al.1995 · 8 citationsEuropean journal of biochemistry. 1994;226(2):567-76
Career total: 138 works. 34 are in this corpus.Showing the 33 most recent.
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