XY
Xiaohan Yuan
Drug Design[1,2,4]triazolo[1,5-a]pyrimidinesAntiproliferative activityMachine LearningAntitumor activityApoptosiscs.CVLSD1 inhibitors[1, 2, 4] triazolo[1, 5- a] pyrimidine1, 2, 4] triazolo[1, 5-a] pyrimidines
On Valency
published · living versionsW_ecdwuwe6·v1 · currentpublished
PGuard: A Native, Streaming, and Plug-in Guardrail for Multimodal Large Language Models
with Junyu Lin, Mengjie Wu, Yonghao Dong, Yuchuan Fu +9
1 version
Preprints & journals
20 papers in the corpus · 2018–2025Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets.41083026 · Shah, Keyur D, Chamseddine, Ibrahim, Yuan, Xiaohan et al.2026 · 2 citationsInternational journal of radiation oncology, biology, physics. 2026;124(3):856-867
GraspDiff: Grasping Generation for Hand-Object Interaction With Multimodal Guided Diffusion.39312427 · Zuo, Binghui, Zhao, Zimeng, Sun, Wenqian et al.2025 · 7 citationsIEEE transactions on visualization and computer graphics. 2025;31(9):5642-5654
RAS-Eval: A Comprehensive Benchmark for Security Evaluation of LLM Agents in Real-World Environments2506.15253v1 · Yuchuan Fu, Xiaohan Yuan, Dongxia Wang2025 · 0 citationsarXiv
NP-Hand: Novel Perspective Hand Image Synthesis Guided by Normals.40249692 · Zuo, Binghui, Sun, Wenqian, Zhao, Zimeng et al.2025 · 1 citationIEEE transactions on image processing : a publication of the IEEE Signal Processing Society. 2025;34:2435-2449
Machine learning in image-based outcome prediction after radiotherapy: A review.39556691 · Yuan, Xiaohan, Ma, Chaoqiong, Hu, Mingzhe et al.2025 · 16 citationsJournal of applied clinical medical physics. 2025;26(1):e14559
4D Myocardium Reconstruction with Decoupled Motion and Shape Model2308.14083v1 · Xiaohan Yuan, Cong Liu, Yangang Wang2023 · 12 citationsarXiv
Alternaria alternata F3, a Novel Taxol-Producing Endophytic Fungus Isolated from the Fruits of Taxus cuspidata: Isolation, Characterization, Taxol Yield Improvement, and Antitumor Activity.37498379 · Fu, Yuefeng, Li, Xinyue, Yuan, Xiaohan et al.2024 · 14 citationsApplied biochemistry and biotechnology. 2024;196(4):2246-2269
DiffuseExpand: Expanding dataset for 2D medical image segmentation using diffusion models2304.13416v2 · Shitong Shao, Xiaohan Yuan, Zhen Huang et al.2023 · 6 citationsarXiv
A novel early diagnostic framework for chronic diseases with class imbalance.35597855 · Yuan, Xiaohan, Chen, Shuyu, Sun, Chuan et al.2022 · 20 citationsScientific reports. 2022;12(1):8614
Simultaneous quantification of fourteen characteristic active compounds in Eucommia ulmoides Oliver and its tea product by ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry (UPLC-QqQ-MS/MS).35504080 · Li, Xin-Yue, Fu, Yu-Jie, Fu, Yue-Feng et al.2022 · 37 citationsFood chemistry. 2022;389:133106
G2Basy: A framework to improve the RNN language model and ease overfitting problem.33852595 · Yuwen, Lu, Chen, Shuyu, Yuan, Xiaohan2021 · 4 citationsPloS one. 2021;16(4):e0249820
FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.33540357 · Wang, Shuai, Yuan, Xiao-Han, Wang, Sai-Qi et al.2021 · 155 citationsEuropean journal of medicinal chemistry. 2021;214:113218
Discovery of [1,2,4]triazolo[1,5-a]pyrimidines derivatives as potential anticancer agents.33385852 · Huo, Jin-Ling, Wang, Shuai, Yuan, Xiao-Han et al.2021 · 42 citationsEuropean journal of medicinal chemistry. 2021;211:113108
Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators.33280384 · Wang, Shuai, Wang, Sai-Qi, Teng, Qiu-Xu et al.2021 · 48 citationsJournal of medicinal chemistry. 2020;63(24):15979-15996
Discovery of tofacitinib derivatives as orally active antitumor agents based on the scaffold hybridization strategy.32682202 · Shi, Xiao-Jing, Wang, Shuai, Li, Xiao-Jing et al.2021 · 15 citationsEuropean journal of medicinal chemistry. 2020;203:112601
Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway.32683165 · Wang, Shuai, Ma, Xu-Bin, Yuan, Xiao-Han et al.2021 · 20 citationsEuropean journal of medicinal chemistry. 2020;203:112630
Drug repurposing: Discovery of troxipide analogs as potent antitumor agents.32619887 · Lu, Nan, Huo, Jin-Ling, Wang, Shuai et al.2021 · 14 citationsEuropean journal of medicinal chemistry. 2020;202:112471
Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors.30780087 · Wang, Shuai, Li, Zhong-Rui, Suo, Feng-Zhi et al.2019 · 59 citationsEuropean journal of medicinal chemistry. 2019;167:388-401
Experience-based discovery (EBD) of aryl hydrazines as new scaffolds for the development of LSD1/KDM1A inhibitors.30739825 · Li, Zhong-Rui, Wang, Shuai, Yang, Linlin et al.2019 · 38 citationsEuropean journal of medicinal chemistry. 2019;166:432-444
Association between EGFR/KRAS mutation and expression of VEGFA, VEGFR and VEGFR2 in lung adenocarcinoma.30008907 · Yuan, Xiao-Han, Yang, Jie, Wang, Xin-Yue et al.2020 · 30 citationsOncology letters. 2018;16(2):2105-2112
Career total: 48 works. 20 are in this corpus.
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