SR
Stephen I. Ryu
Brain-Computer InterfacesUser-Computer InterfaceProstheses and ImplantsAlgorithmsModels, Neurologicalmotor controlmotor cortexneuroscienceAccelerationCommunication Devices for People with Disabilities
On Valency
published · living versionsW_nbbzknup·v1 · currentpublished
Making brain-machine interfaces robust to future neural variability
with David Sussillo, Sergey D. Stavisky, Jonathan C. Kao, Krishna V. Shenoy
1 version
Preprints & journals
66 papers in the corpus · 2006–2026Signatures of Covert Neuron Loss in the Local Field Potential of Motor Cortex.42466505 · Marshall, Kenji, Clarke, Stephen E, Bray, Iliana E et al.2026 · 0 citationsJournal of the American Heart Association. 2026;15(14):e047091
An Integrated 3-Dimentional Navigation System Increases the Accuracy, Efficiency, and Safety of Percutaneous Thoracolumbar Pedicle Screw Placement in Minimally Invasive Approaches: A Randomized Cadaveric Study.38165219 · Lakomkin, Nikita, Eastlack, Robert K, Uribe, Juan S et al.2025 · 3 citationsGlobal spine journal. 2025;15(2):1099-1105
A Non-Human Primate Brain-Computer Typing Interface.33746239 · Nuyujukian, Paul, Kao, Jonathan C, Ryu, Stephen I et al.2024 · 26 citationsProceedings of the IEEE. Institute of Electrical and Electronics Engineers. 2017;105(1):66-72
Learning leaves a memory trace in motor cortex.38531360 · Losey, Darby M, Hennig, Jay A, Oby, Emily R et al.2024 · 29 citationsCurrent biology : CB. 2024;34(7):1519-1531.e4
Expanding the Scope of Robotic Spinal Surgery With Bone Decompression: Commentary on "Advancements and Challenges in Robot-Assisted Bone Processing in Neurosurgical Procedures".38569636 · Ryu, Stephen2024 · 0 citationsNeurospine. 2024;21(1):104-105
Learning alters neural activity to simultaneously support memory and action10.1101/2022.07.05.498856v1 · Losey, D. M., Hennig, J. A., Oby, E. R. et al.2022 · 12 citationsbioRxiv
Structure in Neural Activity during Observed and Executed Movements Is Shared at the Neural Population Level, Not in Single Neurons.32905762 · Jiang, Xiyuan, Saggar, Hemant, Ryu, Stephen I et al.2021 · 15 citationsCell reports. 2020;32(10):108148
Combining Wireless Neural Recording and Video Capture for the Analysis of Natural Gait.26019730 · Foster, Justin D, Freifeld, Oren, Nuyujukian, Paul et al.2020 · 16 citationsInternational IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering. 2011;2011:613-616
Causal Role of Motor Preparation during Error-Driven Learning.32053768 · Vyas, Saurabh, O'Shea, Daniel J, Ryu, Stephen I et al.2020 · 91 citationsNeuron. 2020;106(2):329-339.e4
Corrigendum: Making brain-machine interfaces robust to future neural variability.28106034 · Sussillo, David, Stavisky, Sergey D, Kao, Jonathan C et al.2020 · 5 citationsNature communications. 2017;8:14490
Skill-specific changes in cortical preparatory activity during motor learning10.1101/2020.01.30.919894v1 · Sun, X., O'Shea, D. J., Golub, M. D. et al.2020 · 13 citationsbioRxiv
Single Neuron Firing Rate Statistics in Motor Cortex During Execution and Observation of Movement.30440555 · Jiang, Xiyuan, Ryu, Stephen I, Shenoy, Krishna V et al.2019 · 0 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2018;2018:981-986
Simultaneous motor preparation and execution in a last-moment reach correction task.31221968 · Ames, K Cora, Ryu, Stephen I, Shenoy, Krishna V2019 · 109 citationsNature communications. 2019;10(1):2718
Structure and variability of delay activity in premotor cortex.30794541 · Even-Chen, Nir, Sheffer, Blue, Vyas, Saurabh et al.2019 · 35 citationsPLoS computational biology. 2019;15(2):e1006808
Leveraging neural dynamics to extend functional lifetime of brain-machine interfaces.28784984 · Kao, Jonathan C, Ryu, Stephen I, Shenoy, Krishna V2019 · 47 citationsScientific reports. 2017;7(1):7395
Constraints on neural redundancy.30109848 · Hennig, Jay A, Golub, Matthew D, Lund, Peter J et al.2019 · 85 citationseLife. 2018;7
Augmenting intracortical brain-machine interface with neurally driven error detectors.29130452 · Even-Chen, Nir, Stavisky, Sergey D, Kao, Jonathan C et al.2018 · 37 citationsJournal of neural engineering. 2017;14(6):066007
Leveraging historical knowledge of neural dynamics to rescue decoder performance as neural channels are lost: "Decoder hysteresis".26736448 · Kao, Jonathan C, Ryu, Stephen I, Shenoy, Krishna V2018 · 4 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2015;2015:1061-6
Motor Cortical Visuomotor Feedback Activity Is Initially Isolated from Downstream Targets in Output-Null Neural State Space Dimensions.28625485 · Stavisky, Sergey D, Kao, Jonathan C, Ryu, Stephen I et al.2017 · 131 citationsNeuron. 2017;95(1):195-208.e9
A High-Performance Neural Prosthesis Incorporating Discrete State Selection With Hidden Markov Models.27337709 · Kao, Jonathan C, Nuyujukian, Paul, Ryu, Stephen I et al.2017 · 89 citationsIEEE transactions on bio-medical engineering. 2017;64(4):935-945
Making brain-machine interfaces robust to future neural variability1610.05872v1 · David Sussillo, Sergey D. Stavisky, Jonathan C. Kao et al.2016 · 236 citationsNature Communications. 7:13749 (2016)on Valency
Auto-deleting brain machine interface: Error detection using spiking neural activity in the motor cortex.26736203 · Even-Chen, Nir, Stavisky, Sergey D, Kao, Jonathan C et al.2016 · 7 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2015;2015:71-5
Single-unit activity, threshold crossings, and local field potentials in motor cortex differentially encode reach kinematics.26133797 · Perel, Sagi, Sadtler, Patrick T, Oby, Emily R et al.2016 · 61 citationsJournal of neurophysiology. 2015;114(3):1500-12
Single-trial dynamics of motor cortex and their applications to brain-machine interfaces.26220660 · Kao, Jonathan C, Nuyujukian, Paul, Ryu, Stephen I et al.2016 · 206 citationsNature communications. 2015;6:7759
Hybrid decoding of both spikes and low-frequency local field potentials for brain-machine interfaces.25570632 · Stavisky, Sergey D, Kao, Jonathan C, Nuyujukian, Paul et al.2015 · 10 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2014;2014:3041-4
Comparison of spike sorting and thresholding of voltage waveforms for intracortical brain-machine interface performance.25504690 · Christie, Breanne P, Tat, Derek M, Irwin, Zachary T et al.2015 · 117 citationsJournal of neural engineering. 2015;12(1):016009
Brain-computer interface control along instructed paths.25605498 · Sadtler, P T, Ryu, S I, Tyler-Kabara, E C et al.2015 · 22 citationsJournal of neural engineering. 2015;12(1):016015
A high-performance keyboard neural prosthesis enabled by task optimization.25203982 · Nuyujukian, Paul, Fan, Joline M, Kao, Jonathan C et al.2015 · 67 citationsIEEE transactions on bio-medical engineering. 2015;62(1):21-29
Direction and speed tuning of motor-cortex multi-unit activity and local field potentials during reaching movements.24109683 · Perel, Sagi, Sadtler, Patrick T, Godlove, Jason M et al.2015 · 13 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2013;2013:299-302
A freely-moving monkey treadmill model.24995476 · Foster, Justin D, Nuyujukian, Paul, Freifeld, Oren et al.2015 · 79 citationsJournal of neural engineering. 2014;11(4):046020
Self-recalibrating classifiers for intracortical brain-computer interfaces.24503597 · Bishop, William, Chestek, Cynthia C, Gilja, Vikash et al.2014 · 64 citationsJournal of neural engineering. 2014;11(2):026001
Intention estimation in brain-machine interfaces.24654266 · Fan, Joline M, Nuyujukian, Paul, Kao, Jonathan C et al.2014 · 72 citationsJournal of neural engineering. 2014;11(1):016004
Design and validation of a real-time spiking-neural-network decoder for brain-machine interfaces.23574919 · Dethier, Julie, Nuyujukian, Paul, Ryu, Stephen I et al.2014 · 82 citationsJournal of neural engineering. 2013;10(3):036008
A framework for relating neural activity to freely moving behavior.23366491 · Foster, Justin D, Nuyujukian, Paul, Freifeld, Oren et al.2013 · 7 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2012;2012:2736-9
A brain machine interface control algorithm designed from a feedback control perspective.23366141 · Gilja, Vikash, Nuyujukian, Paul, Chestek, Cindy A et al.2013 · 29 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2012;2012:1318-22
A recurrent neural network for closed-loop intracortical brain-machine interface decoders.22427488 · Sussillo, David, Nuyujukian, Paul, Fan, Joline M et al.2012 · 197 citationsJournal of neural engineering. 2012;9(2):026027
Evaluation of volumetric modulated arc therapy for cranial radiosurgery using multiple noncoplanar arcs.22047350 · Audet, Chantal, Poffenbarger, Brett A, Chang, Pauling et al.2012 · 111 citationsMedical physics. 2011;38(11):5863-72
Long-term stability of neural prosthetic control signals from silicon cortical arrays in rhesus macaque motor cortex.21775782 · Chestek, Cynthia A, Gilja, Vikash, Nuyujukian, Paul et al.2011 · 377 citationsJournal of neural engineering. 2011;8(4):045005
Single-trial neural correlates of arm movement preparation.21835350 · Afshar, Afsheen, Santhanam, Gopal, Yu, Byron M et al.2011 · 286 citationsNeuron. 2011;71(3):555-64
A closed-loop human simulator for investigating the role of feedback control in brain-machine interfaces.20943945 · Cunningham, John P, Nuyujukian, Paul, Gilja, Vikash et al.2011 · 182 citationsJournal of neurophysiology. 2011;105(4):1932-49
Low-dimensional neural features predict muscle EMG signals.21097116 · Rivera-Alvidrez, Zuley, Kalmar, Rachel S, Ryu, Stephen I et al.2011 · 10 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2010;2010:6027-33
Massive spontaneous epidural hematoma in a high-level swimmer: a case report.21123615 · Fleager, Kristen, Lee, Arthur, Cheng, Ivan et al.2011 · 7 citationsThe Journal of bone and joint surgery. American volume. 2010;92(17):2843-6
Neural prosthetic systems: current problems and future directions.19963796 · Chestek, Cindy A, Cunningham, John P, Gilja, Vikash et al.2010 · 47 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009;2009:3369-75
Fracture-related thoracic kyphotic deformity correction by single-stage posterolateral vertebrectomy with circumferential reconstruction and stabilization: Outcomes in 30 cases.20075812 · Yoo, Chanjong, Ryu, Stephen I, Park, Jon2010 · 5 citationsJournal of spinal disorders & techniques. 2009;22(7):492-501
Methods for estimating neural firing rates, and their application to brain-machine interfaces.19349143 · Cunningham, John P, Gilja, Vikash, Ryu, Stephen I et al.2010 · 89 citationsNeural networks : the official journal of the International Neural Network Society. 2009;22(9):1235-46
HermesC: low-power wireless neural recording system for freely moving primates.19497829 · Chestek, Cynthia A, Gilja, Vikash, Nuyujukian, Paul et al.2009 · 136 citationsIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 2009;17(4):330-8
Factor-analysis methods for higher-performance neural prostheses.19297518 · Santhanam, Gopal, Yu, Byron M, Gilja, Vikash et al.2009 · 132 citationsJournal of neurophysiology. 2009;102(2):1315-30
Human cortical prostheses: lost in translation?19569893 · Ryu, Stephen I, Shenoy, Krishna V2009 · 108 citationsNeurosurgical focus. 2009;27(1):E5
The use of a virtual integration environment for the real-time implementation of neural decode algorithms.19162734 · Bishop, William, Yu, Byron M, Santhanam, Gopal et al.2009 · 6 citationsAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2008;2008:628-33
Toward optimal target placement for neural prosthetic devices.18829845 · Cunningham, John P, Yu, Byron M, Gilja, Vikash et al.2009 · 26 citationsJournal of neurophysiology. 2008;100(6):3445-57
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